Monositer Lösemi

1 — Altısı akut, üçü kronik şekle uyan ve yedisi Schilling tipinde, ikisi Naegeli tipinde bulunan dokuz adet monositer lösemi vak'ası takdim olundu. 2 — Monositer löseminin teşhisinde karşılaşılan güçlüklerin iki sebebden ileri geldiğine işaret olundu. Bu sebeblerden bir tanesinin monositer löseminin retiküsarkom ve Hodgkin hastalığı ile akraba olmasından, diğerinin monositlerin idantifikasyonunda rastlanan güçlükten ibaret bulunduğu vak'alara dayanılarak açıklandı. 3 — Monositer löseminin kronik şeklinin mevcut bulunduğu ve bunun zannedildiği kadar nadir olmadığı tebarüz ettirildi. 4 — Takdim olunan dokuz adet monositer lösemi vak'ası klinik ve hematolojik özellikleri bakımından münakaşa edildi ve literatürdeki vak'alarla karşılaştırıldı. Naegeli tipinin daha ziyade kronik, Schilling tipinin ise tercihan akut seyretmek temayülünde bulundugu kanaatı ortaya konuldu. 5 — Literatürdeki bilgilere göre monositer lösemi vak'alarında antibiotik, transfüziyon ve steroit yanında NH. ve deriveleri ile 6 - MP'nin kullanılmasının uygun olacağına işaret edildikten sonra bu yazıda takdim olunan vak'alarda elde edilen tedavi sonuçlarına dayanılarak monositer lösemi tedavisinin, bilhassa tedavisi gecikmiş vak'alarda, yüz güldürücü olmadığı kanaatı tebrüz ettirildi.

1 — Nine cases of monocytic leukemia were presented, six of which were acute, three of which were chronic, seven of which were Schilling-type, and two of which were Naegeli-type. 2 — It was pointed out that the difficulties encountered in diagnosing monocytic leukemia stemmed from two reasons. One of these reasons was explained based on the cases: the relatedness of monocytic leukemia to reticulum sarcoma and Hodgkin's disease, and the other was the difficulty encountered in identifying monocytes. 3 — It was demonstrated that a chronic form of monocytic leukemia exists and that it is not as rare as previously thought. 4 — The nine cases of monocytic leukemia were discussed in terms of their clinical and hematological characteristics and compared with cases in the literature. It was concluded that the Naegeli type tends to be chronic, while the Schilling type tends to be acute. 5 — After pointing out that, according to literature, the use of NH and its derivatives, along with 6-MP, would be appropriate in cases of monocytic leukemia, along with antibiotics, transfusions, and steroids, it was concluded that, based on the treatment results obtained in the cases presented in this article, the treatment of monocytic leukemia, especially in cases with delayed treatment, is not satisfactory.