Astma Hastalığının Patojeni ve Etiyolojisi Hakkında
Abstract
Wheezing and lung hyperinflation in asthma are due to bronchial constriction and air trapping. Toward the end of an asthma attack, patients often produce thick sputum containing Curschmann spirals, Charcot-Leiden crystals, and eosinophils. The formation of this sputum cannot be fully explained by neural mechanisms alone. Some investigators suggest a combination of vasomotor changes and mucosal secretion disorders. Current theories often consider both neurogenic and secretory mechanisms to explain the pathogenesis of asthma.
Keywords
References
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