Systematic Reviews and Meta Analysis

Melkersson-Rosenthal Syndrome

Volume: 15 Number: 1-2 December 12, 1956
Lütfü Tat
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Melkersson-Rosenthal Syndrome

Abstract

A 32-year-old male presented with a two-year history of recurrent swelling of the face, lips, and tongue. Tongue swelling caused speech difficulty; lips were cyanotic and firm-elastic. Buccal mucosa showed lobulation (bucca lobata), gingival edema, and plicated appearance of the hard and soft palate. The tongue demonstrated marked fissures (lingua plicata) and edema. No facial nerve palsy was detected. Biopsy of the lip and tongue revealed edema, acanthosis, dense lymphocytic and epithelioid cell infiltrates, and Langhans-type giant cells. Clinical and histological findings were consistent with Melkersson–Rosenthal syndrome. Although the etiology is unclear, it is thought to be related to granulomatous cheilitis. Cortisone is considered the most effective treatment, but was unavailable; partial improvement was achieved with streptomycin, isonicotinic acid hydrazide, and antihistamines.

Keywords

Melkersson–Rosenthal syndrome, Lingua plicata, Macrocheilia

References

  1. 1. Lüscher E. Syndrom von Melkersson–Rosenthal. Schweiz Med Wschr. 1949; Nr.1: 11–18.
  2. 2. Jordan P, Reidhel K. Das Melkersson–Rosenthal–Syndrom. Der Hautarzt. 1950; 1: 37–89.
  3. 3. Gahlen W, Brückner B. Beiträge zur Pathogenese des Melkersson–Rosenthal–Syndroms. Arch Derm. 1951; 192: 408–477.
  4. 4. Scheuermann H. Glossitis und Parotitis Granulomatosa. Der Hautarzt. 1952; 12: 538–542.
  5. 5. Hornstein O. Beteiligung des lymphatischen Systems am Komplex der Cheilitis granulomatosa. Arch Derm. 1954; 198: 396–416.
  6. 6. Hornstein O. Klinische und histologische Untersuchungen über Cheilitis granulomatosa (Miescher) bzw. Melkersson–Rosenthal–Syndrom. Der Hautarzt. 1955; 10: 433–447.
  7. 7. Landes E, Hewger R. Melkersson–Rosenthal–Syndrom. Der Hautarzt. 1958; 9: 440.
  8. 8. Hering H, Scheid P. Kritische Bemerkungen zum M.–R.–Syndrom als Teilbild des Morbus Besnier–Boeck–Schaumann. Arch Derm. 1954; 194: 344–382.
  9. 9. Touraine RL. Le Syndrome de Melkersson–Rosenthal. Ann Dermat Syph. 1954; 81: 409.
  10. 10. Jordan P, Reichel K. Das Melkersson–Rosenthal–Syndrom. Der Hautarzt. 1950; 1: 37–89.

Details

Primary Language

English

Subjects

Dermatology

Journal Section

Systematic Reviews and Meta Analysis

Authors

Lütfü Tat This is me
Türkiye

Publication Date

December 12, 1956

Submission Date

January 1, 1956

Acceptance Date

June 30, 1956

Published in Issue

Year 1956 Volume: 15 Number: 1-2

IZ

https://izlik.org/JA55WJ39SC

Cite

RIS / Bibtex
APA
Tat, L. (1956). Melkersson-Rosenthal Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 15(1-2), 5-12. https://izlik.org/JA55WJ39SC
AMA
1.Tat L. Melkersson-Rosenthal Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1956;15(1-2):5-12. https://izlik.org/JA55WJ39SC
Chicago
Tat, Lütfü. 1956. “Melkersson-Rosenthal Syndrome”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 15 (1-2): 5-12. https://izlik.org/JA55WJ39SC.
EndNote
Tat L (December 1, 1956) Melkersson-Rosenthal Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası 15 1-2 5–12.
IEEE
[1]L. Tat, “Melkersson-Rosenthal Syndrome”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 15, no. 1-2, pp. 5–12, Dec. 1956, [Online]. Available: https://izlik.org/JA55WJ39SC
ISNAD
Tat, Lütfü. “Melkersson-Rosenthal Syndrome”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 15/1-2 (December 1, 1956): 5-12. https://izlik.org/JA55WJ39SC.
JAMA
1.Tat L. Melkersson-Rosenthal Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1956;15:5–12.
MLA
Tat, Lütfü. “Melkersson-Rosenthal Syndrome”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 15, no. 1-2, Dec. 1956, pp. 5-12, https://izlik.org/JA55WJ39SC.
Vancouver
1.Lütfü Tat. Melkersson-Rosenthal Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1956 Dec. 1;15(1-2):5-12. Available from: https://izlik.org/JA55WJ39SC