Akut Porphyria
Abstract
Acute intermittent porphyria is a rare metabolic disorder that mimics various acute abdominal syndromes and neuropsychiatric conditions. It typically manifests between ages 20–40, more commonly in women, and presents with episodic abdominal pain, constipation, tachycardia, hypertension, peripheral neuropathy, and psychiatric symptoms. Diagnosis is confirmed by detecting porphobilinogen in urine. A 32-year-old female patient with recurrent attacks over seven years showed gastrointestinal, urinary, and neuropsychiatric symptoms. She responded positively to treatment with calcium EDTA, a chelating agent. The case highlights the diagnostic challenges and therapeutic potential of chelation therapy in acute porphyria.
Keywords
acute intermittent porphyria, porphobilinogen, abdominal pain
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