Toksoplazmoz Tanısı

Abstract

Keywords

• -

Toksoplazmoz Tanısı

Abstract

Toksoplazmoz, Apikompleksan bir protozoon olan Toxoplasma gondii’nin etken olduğu bir paraziter hastalıktır. İmmunkompetan kişilerde çoğunlukla asemptomatik, kendini sınırlayan nezle benzeri bir tablo veya lokal lenfadenopati ile seyrederken; immun yetmezliği olanlarda ve enfekte fetus veya yenidoğanlarda ölümle sonuçlanabilen ağır tablolara yol açabilmektedir. Histolojik tanı veya organizmanın izolasyonu zor ve zaman alıcı olduğu için, tanıda esas olarak serolojik tanı yöntemleri kullanılmaktadır. Bu derlemede, toksoplazmoz tanısında değişik hasta gruplarında kullanılabilecek antikor tipleri ve serolojik yöntemler gözden geçirilmiştir. Özellikle toksoplazmoz tanısının önemli ama zor olduğu gebeler ve yeni doğanlarda öne çıkan bazı yeni ve geliştirilmiş tanı yöntemlerinden bahsedilmiş ve serolojik testlerin yorumlanmasında karşılaşılabilecek sorunlar özetlenmiştir.

Keywords

• Toxoplasma gondii, tanı, seroloji, gebelik, immunkompromize

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