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Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case

Year 2017, Volume: 70 Issue: 2, 106 - 109, 20.08.2017

Hande Selvi Öztorun

https://doi.org/10.1501/Tipfak_0000000973

Abstract

Merkel cell carcinoma (MCC) is a rare skin tumor that usually develops in elderly and sunexposed body regions. The tumor is aggressive in nature, and in the case of delayed diagnosis, the treatment is difficult and the prognosis is poor. MCC is rarely seen on the ground of chronic venous insufficiency and on the lower extremity. In this case, an 85-year-old male patient was diagnosed with Merkel cell carcinoma in the right leg, biopsy specimen taken from a ulcer and a raised lysole from chronic venous insufficiency after cardiac bypass graft surgery for cardiac bypass surgery. Skin malignancies such as MCC should be kept in mind in the differential diagnosis of venous ulcers and other skin lesions that may develop frequently on the basis of chronic venous insufficiency. 

Keywords

Merkel Cell Carcinoma Chronic Venous Insufficiency

References

  • 1. Tothill R, Estall V, Rischin D, Merkel cell carcinoma: emerging biology, current approaches, and future directions. Am Soc Clin Oncol Educ Book 2015:519-26.
  • 2. Heath M, Jaimes N, Lemos B, et al., Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. J Am Acad Dermatol 2008. 58:375-81.
  • 3. Peterson CM, Lane JE, Guill MA, Merkel cell carcinoma after postmastectomy lymphedema. J Am Acad Dermatol 2003. 48:983.
  • 4. Lee R, Saardi KM, Schwartz RA, Lymphedema-related angiogenic tumors and other malignancies. Clin Dermatol 2014. 32:616-20.
  • 5. Lebbe C, Becker JC, Grob JJ, et al., Diagnosis and treatment of Merkel Cell Carcinoma. European consensusbased interdisciplinary guideline. Eur J Cancer 2015. 51:2396-403.
  • 6. Topham EJ, Mortimer PS, Chronic lower limb oedema. Clin Med (Lond) 2002. 2:28-31.
  • 7. Schwartz RA, Lambert WC, The Merkel cell carcinoma: a 50-year retrospect. J Surg Oncol 2005. 89:5.
  • 8. Alguire PC, Mathes BM, Chronic venous insufficiency and venous ulceration. J Gen Intern Med 1997. 12:374-83.
  • 9. Elgendy IY, Lo MC, Unilateral lower extremity swelling as a rare presentation of non-Hodgkin's lymphoma. BMJ Case Rep 2014;doi:10.1136/bcr-2013-202424
  • 10. Ultori C, Cimetti L, Stefanoni P, et al., Merkel cell carcinoma in elderly: case report and review of the literature. Aging Clin Exp Res 2013. 25:211-4.
  • 11. Kampshoff JL, Cogbill TH, Unusual skin tumors: Merkel cell carcinoma, eccrine carcinoma, glomus tumors, and dermatofibrosarcoma protuberans. Surg Clin North Am 2009. 89:727-38

Year 2017, Volume: 70 Issue: 2, 106 - 109, 20.08.2017

Hande Selvi Öztorun

https://doi.org/10.1501/Tipfak_0000000973

Abstract

References

  • 1. Tothill R, Estall V, Rischin D, Merkel cell carcinoma: emerging biology, current approaches, and future directions. Am Soc Clin Oncol Educ Book 2015:519-26.
  • 2. Heath M, Jaimes N, Lemos B, et al., Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. J Am Acad Dermatol 2008. 58:375-81.
  • 3. Peterson CM, Lane JE, Guill MA, Merkel cell carcinoma after postmastectomy lymphedema. J Am Acad Dermatol 2003. 48:983.
  • 4. Lee R, Saardi KM, Schwartz RA, Lymphedema-related angiogenic tumors and other malignancies. Clin Dermatol 2014. 32:616-20.
  • 5. Lebbe C, Becker JC, Grob JJ, et al., Diagnosis and treatment of Merkel Cell Carcinoma. European consensusbased interdisciplinary guideline. Eur J Cancer 2015. 51:2396-403.
  • 6. Topham EJ, Mortimer PS, Chronic lower limb oedema. Clin Med (Lond) 2002. 2:28-31.
  • 7. Schwartz RA, Lambert WC, The Merkel cell carcinoma: a 50-year retrospect. J Surg Oncol 2005. 89:5.
  • 8. Alguire PC, Mathes BM, Chronic venous insufficiency and venous ulceration. J Gen Intern Med 1997. 12:374-83.
  • 9. Elgendy IY, Lo MC, Unilateral lower extremity swelling as a rare presentation of non-Hodgkin's lymphoma. BMJ Case Rep 2014;doi:10.1136/bcr-2013-202424
  • 10. Ultori C, Cimetti L, Stefanoni P, et al., Merkel cell carcinoma in elderly: case report and review of the literature. Aging Clin Exp Res 2013. 25:211-4.
  • 11. Kampshoff JL, Cogbill TH, Unusual skin tumors: Merkel cell carcinoma, eccrine carcinoma, glomus tumors, and dermatofibrosarcoma protuberans. Surg Clin North Am 2009. 89:727-38
There are 11 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Hande Selvi Öztorun

Publication Date August 20, 2017
Published in Issue Year 2017 Volume: 70 Issue: 2

Cite

APA Öztorun, H. S. (2017). Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 70(2), 106-109. https://doi.org/10.1501/Tipfak_0000000973
AMA Öztorun HS. Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case. Ankara Üniversitesi Tıp Fakültesi Mecmuası. August 2017;70(2):106-109. doi:10.1501/Tipfak_0000000973
Chicago Öztorun, Hande Selvi. “Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 70, no. 2 (August 2017): 106-9. https://doi.org/10.1501/Tipfak_0000000973.
EndNote Öztorun HS (August 1, 2017) Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case. Ankara Üniversitesi Tıp Fakültesi Mecmuası 70 2 106–109.
IEEE H. S. Öztorun, “Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 70, no. 2, pp. 106–109, 2017, doi: 10.1501/Tipfak_0000000973.
ISNAD Öztorun, Hande Selvi. “Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 70/2 (August 2017), 106-109. https://doi.org/10.1501/Tipfak_0000000973.
JAMA Öztorun HS. Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2017;70:106–109.
MLA Öztorun, Hande Selvi. “Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 70, no. 2, 2017, pp. 106-9, doi:10.1501/Tipfak_0000000973.
Vancouver Öztorun HS. Merkel Cell Carcinoma Secondary to Chronic Venous Insufficiency, A Rare Case. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2017;70(2):106-9.