Antibiotic Coverage in Surgical Neonates, a Comparison of Ceftazidime, Ceftriaxone and Cefotaxime

Year 1993, Volume: 46 Issue: 3, 479 - 486, 30.09.1993

Hilmi Dindar

Abstract

In order to define the appropriate antibiotics for surgical neonates, causative microbial agents of domestic infection and sensitive antibiotics to these agents has been evaluated retrospectively for 6 months period in Ankara University Cebeci Hospitals. Amikacin for gram negatives and Ceftadizime, Ceftriaxone, and Ceftadizime for gram positives has been preferred due to their safeness in usage in surgical neonates and results of preliminary study of antibiograms. Tree regimens of antibiotics has been used in almost homogen 42 surgical, neonates. As far as concerned the sepsis and wound infection, the coverage rate of Ceftadizime + Amikacin was 92.8 % , while Ceftriaxone + Amikacin and Cefotaxime + Arnikacin have a rate of 78.57 % and 85.71 % respectively.

Keywords

: Surgical neonate , Infection , Antibiotic coverage

Ethical Statement

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CERRAHİ YENİDOĞANLARDA ANTİBİYOTİK REJİMLERİNİN KARŞILAŞTIRILMASI

Abstract

Cerrahi yenidoğanlarda koruyucu amaçla kullanılabilen antibiyetiklerin uygun seçimini yapmak amacıyla, hastanelerde alınan kültürlerde üreyen mikroorganizmalar ve duyarlı oldukları antibiyotikler belirlenmişler, bu antibiyotiklerden yenidoğanlarda kullanımları uygun olan, Gr (—) ler için Amikacin, Gr ( -F) için Ceftazidime, Ceftriaxone ve Cefotaxime seçilerek : Ceftazidime + Arnikasin, Ceftria xone + Amikasin ve Cefotaxime 4- Arnikasin şeklinde antibiyotik grupları oluşturulmuştur. Bu rejimler mümkün olduğunca homojen olarak gruplandırılan 42 yenidoğanda uygulanmış ve Ceftazidime + Venidoùanlarda karşılaştırılması. Amikasin grubunda % 92.8. Ceftriaxone + Arnikasin grubunda % 78.6 ve Cefotaxime + Amikasin grubunda % 85.7 oranlarmda koruyuculuk sağlandığı görülmüstür. Değişik özellik ve mikroorganizmalarda ya olan bu karşılaştırmada sayıların azalması nedeniyle istatistik inceleme yapılamamıştır.".

Keywords

cerrahi yenidoğan , enfeksiyon , antibiyotik koruması

Ethical Statement

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Project Number

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References

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