In 9 cases of Botilinum intoxication, clinic examination and conventional ENMG were performed on admission (about 3 days after ingestion of the toxin) and 2 months after admission. On the first examination, 9 cases complained of malaise, nausea, vomiting, abdominal pains, meteorism, constipation, dry mouth, dysphagia, dysphonia, blurred vision, ptosis, generalized weakness. Symptoms and signs had appeared 48 hours after ingestion and they normalized 2 months later.Neurophysiological investigations revealed normal motor and sensorial conduction velocities. Compound muscle action potential (MAP) evoked by single supramaximal sitmulation of the median nerve was rather small in 7 cases, the MAP amplitude progressively increased at fast rates of repetative stimulation in 5 cases, 1 case Myasthenic type decrement was also present. On the second examination which was carried 2 months after poisoning, the MAP amplitude increased and normalized in 6 cases, during fast repetative stimulation negative phase MAP amplitude increased no more than % 15 in 2 cases, but decrement was also present in 1 case.
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Bu çalışmada botilismus zehirlenmesi tanısı alan 9 hasta tani konulduktan 3 gün sonra ve 2 ay sonra klinik ve ENMG ile değerlendirilmistir. Klinik muayenede; ağız kuruluğu, bulantı kusma, gaz Şikayeti, kabızlık, mukoza hiperemisi, hiporeflexi, midriasis, diplopi, bulanık görme, pitoz, yutma güçlüğü, ses kısıklığı, güçsüzlük, solunum güçlüğü gibi semptom ve bulgular hastalarda değişik sşddetlerde tesbit edilmiştir, Kontrol muayenelerinde bu semptomatolojilerin 5 hastada kaybolduğu, 4 hastada ise birkaç semptom ve işaretin hafifleyerek devam ettiği bulunmuştur. ENMG incelemesinde/hastada teksupramaximal stimuluslarla motor cevap amplittidlerinde dtisme, 5 hastada tetanik stimuluslarla motor cevap amplittidlerinde % 50-100oraninda artislar, 1 hastada myastenik tipde düşme, 3 hastada seyrek stimuluslarla amplittid dtigmesi bulunmşstur. Hastalarm 2 ay sonra yapılan ENMG incelenmesinde; 6 hastada motor cevap amplittidleri normale dönmüş, 2 hastada tetanik stimuluslarla amplitiid artim, 1 hastada tetanik stimuluslarla amplittid dtismesi bulunmustur.
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| Primary Language | English |
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| Subjects | Neurology and Neuromuscular Diseases |
| Journal Section | Articles |
| Authors | |
| Project Number | - |
| Publication Date | June 30, 1990 |
| Published in Issue | Year 1990 Volume: 43 Issue: 2 |