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High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis

Year 1984, Volume: 37 Issue: 2, 117 - 126, 30.06.1984

Gönül Öcal

Abstract

Low-dose intravenous continous insülin administration and highdose intermittent subcutaneously administered insülin therapy were compared in 26 diabetic ketoacidosis. Out of 26 patients, 18 cases received high-dose and 8 cases Iow dose insülin. İn high dose group. Metabolic control were obtained, in 18 29 hours with 2.3 0.16 kg/day insülin, whereas in the Iow-dose group in 3.7 0.17 hourswith 0.70 0.11. Ü/kg/day insülin.

Keywords

intravenous highdose insulin diabetic ketoacidosis

References

  • 1.Albertini K, Hockaday T.D and Turner RC. : Small doses of. intramusculer in Sülin treatment of diabetic coma. Lancet. 2 : 515, 1973.
  • 2.Albertini, KG. ; Low dose insülin in the treatment of. diabetic ketoasidosis Arch. Intern Med. 137 : 1367, 1977.
  • 3. Christensen N.J, and Orskow H. : The relationship between endogenous şemm insülin concentration and glucose uptake in the forearm muscle of non-diabe tics. J. Clin. Invest 47 : 1261, 1968.
  • 4 - Erkol E, Vidinlisan S, Özsoylu Ş. 2 Diabetik ketoasidosiste düşük doz insülinle infüzyon tedavisi Hacettepe. Çocuk Sağlığı ve Hastalıkları Dergisi 18 : 233, 1975.
  • 5 - Fısher JN, Shahshahani MN, Kitabchi AE : Diabetic ketoasidosis : Low-dose in sulin therapy by veriğous routes. N. Engl J. Med. 297, 238, 1977.
  • 6.Galloway J.A, and Shuman CR : Diabetes and surgery. Am. J. Med. 34 : 177, 1963.
  • 7 - Golden M.P, Myers G.L, Tanner Sm, Marrers DG, and Charles MA : Insulin de pendent diabetes Pediatrics. 70 : 36, 1982.
  • 8. Hockaday J.D and Aiberti KG ;Diabetic coma. Clin. Endocrinol Metab. •I : 751, 1972.
  • 9.Kaufman IA, Keler MA, Nyhan WL. Diabetic ketosis and acidosis : The continuous infusion of low doses of insulin. J. Pediatr. 87 : 846, 1975.
  • 10 - Koložlu S, Erdogan G, Kamel N, Koloälu B. : Diabetik ketoasidozun daimi küçük doz insulin infüzyonu ile tedavisi] A.Ü. TIP Fak. Mecm. 30 : 662, 1977.
  • 11 - Korugan (j, Sipahiožlu F, Yüksel .M, Yllmaz MT, Hatemi H, Biyal F : Agrr dia betik ketoasidozda (ADK) iki tedavi yönteminin karsllastlnlmasl ve ADK'dan sonraki dönemde uygulanan insulin tedavisinin degerlendirilmesi. Türk. Endok. 12 - Kreisberg RA. : Diabetic ketoasidosis : New concept. and trends in pathogenesis and treatment. Ann. Intern. Med. 82 : 681, 1978.
  • 13 - Lightner ES, Kappy MS ,Revsin B : Low-dose intravenous insulin infusion in patient with. diabetic ketoasidosis. Pediatrics. 60 : 681, 1977.
  • 14 - Madison, L.L Low-dose insulin. a plea for caution. New. Engl. J. Med. 294 393, 1976.
  • 15 - Malleson PN : Diabetic ketosis in children treated by adding low-dose to rehydrating fluid. : Arch. Dis Child. 51 : 373, 1976.
  • 16 - Mc Dermott M, Cullan MS, : Insulin Treatment of diabetic ketoasidosis Lancet. 1 : 1129, 1982.
  • 17 - Mozeley J. : Diabetic crises in children 'treated with small doses of Intramusb culer insulin. Br. Med. J. I : 59, 1975.
  • 18 - Onur K, Lale V, Juan C.S., Ruskin T&W. : Glucogon suppression with low-dose intramusculer insulin therapy in diabetic acidosis J. Pediatr. 94 : 307, 1979.
  • 19 - Perkin R.M, Marks J.F. : Low-dose continuous intravenous insulin infusion in childhood diabetic ketosidosis, Clin. Ped. 18 : 540, 1979.
  • 20 - Sönksen P.H, Srivastavz MC, Tompkins CV and Nabarra JDN : Growth hor mone, and. Cortisol responses to insulin infusiön in -patients With diabetes mel litus Lancet 2 : 155, 1972.
  • 21.Sperling M.A. : Diabetes Mellitus Ped. Clin. North. Amer. 26 : 149, 1979.
  • 22 - Ternand C, Go V.L.W, Gerich J.E, Hymand MW : Endocrine pancreatic. respon se of children with onset insulin •requiring diabetes before age 3 and after age 5. J. Pediatr. 101 : 36, 1982.
  • 23 - Tomborlane W.V and Genel, M : Discordant correction of hyperglycemia and ketoasidosis with low-dose insulin in(usion. Pediatrics 61 : 125, 1978.
  • 24- Veeser T.E. : Low-Dose intravenous insulin. Therapy for diabetic ketoasidosis in children. Am. J. Dis. Child. 131 : 308, 1977.

Diabetik Ketoasidozun Tedavisinde Yüksek Doz Aralıklı Ve Düşük Doz Sürekli İnsülin Uygulaması

Year 1984, Volume: 37 Issue: 2, 117 - 126, 30.06.1984

Gönül Öcal

Abstract

AÜ. Tıp Fak. Çocuk Sağlığı ve Hastalıkları Kliniği Metabolizma ve Endokrin bölümünde izlenen 26 diabetik ketosidozun 18 inde yüksek doz aralıklı, 8 sinde düşük doz sürekli insülin uygulaması yapılmışeır. Yüksek doz uygulamasında yaklaşık 18 2.9 saatlik bir sürede 2,3 0.16 Ü/kg İlk, infüzyon yapılanlarda ise 3.7 + 0.17 saatlik sürede 0.70 0.11 Ü/kg insülinle metabolik denetim sağlanmıştır

Keywords

İNTERVENÖZ yÜKSEK DOZ İNSÜLİN DİABETİK KETOASİDOZ

References

  • 1.Albertini K, Hockaday T.D and Turner RC. : Small doses of. intramusculer in Sülin treatment of diabetic coma. Lancet. 2 : 515, 1973.
  • 2.Albertini, KG. ; Low dose insülin in the treatment of. diabetic ketoasidosis Arch. Intern Med. 137 : 1367, 1977.
  • 3. Christensen N.J, and Orskow H. : The relationship between endogenous şemm insülin concentration and glucose uptake in the forearm muscle of non-diabe tics. J. Clin. Invest 47 : 1261, 1968.
  • 4 - Erkol E, Vidinlisan S, Özsoylu Ş. 2 Diabetik ketoasidosiste düşük doz insülinle infüzyon tedavisi Hacettepe. Çocuk Sağlığı ve Hastalıkları Dergisi 18 : 233, 1975.
  • 5 - Fısher JN, Shahshahani MN, Kitabchi AE : Diabetic ketoasidosis : Low-dose in sulin therapy by veriğous routes. N. Engl J. Med. 297, 238, 1977.
  • 6.Galloway J.A, and Shuman CR : Diabetes and surgery. Am. J. Med. 34 : 177, 1963.
  • 7 - Golden M.P, Myers G.L, Tanner Sm, Marrers DG, and Charles MA : Insulin de pendent diabetes Pediatrics. 70 : 36, 1982.
  • 8. Hockaday J.D and Aiberti KG ;Diabetic coma. Clin. Endocrinol Metab. •I : 751, 1972.
  • 9.Kaufman IA, Keler MA, Nyhan WL. Diabetic ketosis and acidosis : The continuous infusion of low doses of insulin. J. Pediatr. 87 : 846, 1975.
  • 10 - Koložlu S, Erdogan G, Kamel N, Koloälu B. : Diabetik ketoasidozun daimi küçük doz insulin infüzyonu ile tedavisi] A.Ü. TIP Fak. Mecm. 30 : 662, 1977.
  • 11 - Korugan (j, Sipahiožlu F, Yüksel .M, Yllmaz MT, Hatemi H, Biyal F : Agrr dia betik ketoasidozda (ADK) iki tedavi yönteminin karsllastlnlmasl ve ADK'dan sonraki dönemde uygulanan insulin tedavisinin degerlendirilmesi. Türk. Endok. 12 - Kreisberg RA. : Diabetic ketoasidosis : New concept. and trends in pathogenesis and treatment. Ann. Intern. Med. 82 : 681, 1978.
  • 13 - Lightner ES, Kappy MS ,Revsin B : Low-dose intravenous insulin infusion in patient with. diabetic ketoasidosis. Pediatrics. 60 : 681, 1977.
  • 14 - Madison, L.L Low-dose insulin. a plea for caution. New. Engl. J. Med. 294 393, 1976.
  • 15 - Malleson PN : Diabetic ketosis in children treated by adding low-dose to rehydrating fluid. : Arch. Dis Child. 51 : 373, 1976.
  • 16 - Mc Dermott M, Cullan MS, : Insulin Treatment of diabetic ketoasidosis Lancet. 1 : 1129, 1982.
  • 17 - Mozeley J. : Diabetic crises in children 'treated with small doses of Intramusb culer insulin. Br. Med. J. I : 59, 1975.
  • 18 - Onur K, Lale V, Juan C.S., Ruskin T&W. : Glucogon suppression with low-dose intramusculer insulin therapy in diabetic acidosis J. Pediatr. 94 : 307, 1979.
  • 19 - Perkin R.M, Marks J.F. : Low-dose continuous intravenous insulin infusion in childhood diabetic ketosidosis, Clin. Ped. 18 : 540, 1979.
  • 20 - Sönksen P.H, Srivastavz MC, Tompkins CV and Nabarra JDN : Growth hor mone, and. Cortisol responses to insulin infusiön in -patients With diabetes mel litus Lancet 2 : 155, 1972.
  • 21.Sperling M.A. : Diabetes Mellitus Ped. Clin. North. Amer. 26 : 149, 1979.
  • 22 - Ternand C, Go V.L.W, Gerich J.E, Hymand MW : Endocrine pancreatic. respon se of children with onset insulin •requiring diabetes before age 3 and after age 5. J. Pediatr. 101 : 36, 1982.
  • 23 - Tomborlane W.V and Genel, M : Discordant correction of hyperglycemia and ketoasidosis with low-dose insulin in(usion. Pediatrics 61 : 125, 1978.
  • 24- Veeser T.E. : Low-Dose intravenous insulin. Therapy for diabetic ketoasidosis in children. Am. J. Dis. Child. 131 : 308, 1977.
There are 23 citations in total.

Details

Primary Language English
Subjects Pediatric Surgery
Journal Section Articles
Authors

Gönül Öcal This is me

Publication Date June 30, 1984
Published in Issue Year 1984 Volume: 37 Issue: 2

Cite

APA Öcal, G. (1984). High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 37(2), 117-126.
AMA Öcal G. High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis. Ankara Üniversitesi Tıp Fakültesi Mecmuası. June 1984;37(2):117-126.
Chicago Öcal, Gönül. “High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 37, no. 2 (June 1984): 117-26.
EndNote Öcal G (June 1, 1984) High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis. Ankara Üniversitesi Tıp Fakültesi Mecmuası 37 2 117–126.
IEEE G. Öcal, “High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 37, no. 2, pp. 117–126, 1984.
ISNAD Öcal, Gönül. “High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 37/2 (June 1984), 117-126.
JAMA Öcal G. High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1984;37:117–126.
MLA Öcal, Gönül. “High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 37, no. 2, 1984, pp. 117-26.
Vancouver Öcal G. High-Dose Intermittent and Low-Dose Continuous Insulin Administration in the Treatment of Diabetic Ketoacidosis. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1984;37(2):117-26.
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