Anesthesia in Obstructive Jaundice: A Retrospective Evaluation

Year 1970, Volume: 23 Issue: 6, 1651 - 1664, 31.12.1970

Refik Paykoç

Abstract

Bu retrospektif çalışmada, tıkanma sarılığı bulunan 69 hastaya uygulanan anestezi yöntemlerinin cerrahi sonrası mortalite üzerine etkileri incelenmiştir. Hastaların bir kısmına genel anestezi, diğer kısmına ise epidural anestezi uygulanmıştır. Genel anestezi uygulanan grupta %25,4 oranında mortalite görülürken, epidural anestezi grubunda hiç ölüm kaydedilmemiştir. Bulgular, tıkanma sarılığı olan olgularda epidural anestezinin daha güvenli olabileceğini düşündürmektedir. Bununla birlikte, çalışmanın sınırlı vaka sayısı ve laboratuvar verilerinin yetersizliği nedeniyle daha fazla araştırmaya ihtiyaç vardır.

Keywords

Tıkanma sarılığı , anestezi , epidural anestezi , genel anestezi , mortalite , hepatorenal sendrom , bilirubin , hipotansiyon , karaciğer fonksiyonu , böbrek yetmezliği

Ethical Statement

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Tıkanma Sarılıklarında Anestezi (Retrospektif bir inceleme)

Abstract

In this retrospective study, the effects of different anesthesia methods on postoperative mortality were evaluated in 69 patients with obstructive jaundice. While one group received general anesthesia, the other group received epidural anesthesia. A mortality rate of 25.4% was observed in the general anesthesia group, whereas no deaths occurred in the epidural group. These findings suggest that epidural anesthesia may be a safer option for patients with obstructive jaundice. However, due to the limited number of cases and the lack of detailed laboratory data, further studies are required.

Keywords

Obstructive jaundice , anesthesia , epidural anesthesia , general anesthesia , mortality , hepatorenal syndrome , bilirubin , hypotension , liver function , renal failure

Ethical Statement

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Supporting Institution

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Project Number

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Thanks

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References

• Dawson, B., Jones, R. R., Schnelle, N., Hartridge, V. B., Paulson, J. A.: Surg. Clin. North Amer. 45: 983, 1965.
• De Peyster, F. A., Gilchrist, R. K.: Current Principles Governing Abdominal Surgery of the Aged. Arch. Surg., 83: 154, 1961.
• Doenicke, A., Krumley, J., Kugler, and Klempa, J.: Experimental Studies of the Breakdown of Epontol Determinations of Propanidid in Human Serum. Brit. J. Anesthesia, 40: 415, 1968.
• Drapanas, T., Kluge, D. N. and Schenk, W. G.: Measurement of Hepatic Blood Flow by Bromsulphalein and by the Electromagnetic Flowmeter. Surgery, 48: 1017, 1960.
• Epstein, R. M., Deutsch, S., Cooperman, L. H., Clement, A. J., Price, H. L.: Studies of Splanchnic Circulation during Halothane Anesthesia in Man. Anesthesiology, 26: 246, 1965.
• Galindo, A.: Hepatic Circulation and Hepatic Function during Anesthesia and Surgery. II. Effects of Various Anesthetic Agents. Canad. Anest. Soc. J., 12: 337, 1965.
• Gilbertson, A. A., Boulton, T. T.: Anesthesia in Difficult Situations. Anesthesia, 22: 607, 1967.
• Goldman, V. and Kennedy, P.: Non-Barbiturate Intravenous Anesthetic Report of a Pilot Trial. Anesthesia, 1: 414, 1964.
• Hori, M. W., Austen, W., McDermott Jr. W. V.: Role of Hepatic Arterial Blood Flow and Hepatic Nerves on Renal Circulation and Function I. Acute Studies in the Dog. Ann. Surg., 162: 849, 1965.
• Hori, M. W., Austen, W., McDermott Jr. W. V.: Role of Hepatic Arterial Blood Flow and Hepatic Nerves on Renal Circulation and Function — II. Chronic Studies in the Dog. Ann. Surg., 162: 949, 1965.
• Howells, T. H., Odell, J. R., Hawkins, T. J. and Steane, P. A.: An Introduction to FBA-1420: A New Non-Barbiturate Intravenous Anesthetic. Brit. J. Anesthesia, 36: 195, 1964.
• Jones, R. R., Dawson, B., Atson, M. A., Summerskill, W. H.: Halothane and Nonhalogenated Anesthetic Agents in Patients with Cirrhosis of the Liver. Mortality and Morbidity Following Portal-Systemic Vena Anastomosis.
• Kennedy, Jr., W. F., Sawyer, T. K., Gereeshagen, H. U., Cutler, R. E., Allen, G. D., Bonica, J. J.: Systemic Cardiovascular and Renal Hemodynamic Alteration During Peridural Anesthesia in Normal Man. Anesthesiology, 31: 414, 1969.
• Laidlow, J., Read, A. E. and Sherlock, S.: Morphine Tolerance in Hepatic Cirrhosis. Gastroenterology, 40: 389, 1961.
• Lorhan, P. H., Houske, D., Lanfersieck, R., Shelby, E. A.: Factors Influencing Mortality Following Anesthesia in Gallbladder Surgery. Anesth. Analg., 43: 708, 1964.
• Mithoefer, J.: The Selection and Preparation of Elderly Patients for Operation. Surg. Clin. N. Amer., 40: 871, 1960.
• Ohlsson, E. G.: Liver Blood Studies During and After Various Periods of Total Biliary Obstruction in the Dog. Acta Chir. Scandinav., 135: 55, 1969.
• Price, H. L., Deutsch, S., Cooperman, L. H., Clement, A. J., and Epstein, R. M.: Splanchnic Circulation During Cyclopropane Anesthesia in Normal Man. Anesthesiology, 26: 312, 1965.
• Saidman, L. S., Eger II, E. I.: The Effect of Thiopental Metabolism on Duration of Anesthesia. Anesthesiology, 27: 119, 1966.
• Van Dyke, R. A., and Chenoweth, M. B.: Metabolism of Volatile Anesthetics. Anesthesiology, 26: 348, 1965.