1 — Altısı akut, üçü kronik şekle uyan ve yedisi Schilling tipinde,
ikisi Naegeli tipinde bulunan dokuz adet monositer lösemi
vak'ası takdim olundu.
2 — Monositer löseminin teşhisinde karşılaşılan güçlüklerin
iki sebebden ileri geldiğine işaret olundu. Bu sebeblerden bir tanesinin
monositer löseminin retiküsarkom ve Hodgkin hastalığı ile akraba
olmasından, diğerinin monositlerin idantifikasyonunda rastlanan
güçlükten ibaret bulunduğu vak'alara dayanılarak açıklandı.
3 — Monositer löseminin kronik şeklinin mevcut bulunduğu
ve bunun zannedildiği kadar nadir olmadığı tebarüz ettirildi.
4 — Takdim olunan dokuz adet monositer lösemi vak'ası klinik
ve hematolojik özellikleri bakımından münakaşa edildi ve literatürdeki
vak'alarla karşılaştırıldı. Naegeli tipinin daha ziyade kronik,
Schilling tipinin ise tercihan akut seyretmek temayülünde bulundugu
kanaatı ortaya konuldu.
5 — Literatürdeki bilgilere göre monositer lösemi vak'alarında
antibiotik, transfüziyon ve steroit yanında NH. ve deriveleri
ile 6 - MP'nin kullanılmasının uygun olacağına işaret edildikten
sonra bu yazıda takdim olunan vak'alarda elde edilen tedavi sonuçlarına
dayanılarak monositer lösemi tedavisinin, bilhassa tedavisi
gecikmiş vak'alarda, yüz güldürücü olmadığı kanaatı tebrüz ettirildi.
1 — Nine cases of monocytic leukemia were presented, six of which were acute, three of which were chronic, seven of which were Schilling-type, and two of which were Naegeli-type.
2 — It was pointed out that the difficulties encountered in diagnosing monocytic leukemia stemmed from two reasons. One of these reasons was explained based on the cases: the relatedness of monocytic leukemia to reticulum sarcoma and Hodgkin's disease, and the other was the difficulty encountered in identifying monocytes.
3 — It was demonstrated that a chronic form of monocytic leukemia exists and that it is not as rare as previously thought.
4 — The nine cases of monocytic leukemia were discussed in terms of their clinical and hematological characteristics and compared with cases in the literature. It was concluded that the Naegeli type tends to be chronic, while the Schilling type tends to be acute.
5 — After pointing out that, according to literature, the use of NH and its derivatives, along with 6-MP, would be appropriate in cases of monocytic leukemia, along with antibiotics, transfusions, and steroids, it was concluded that, based on the treatment results obtained in the cases presented in this article, the treatment of monocytic leukemia, especially in cases with delayed treatment, is not satisfactory.
Primary Language | Turkish |
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Subjects | Internal Diseases |
Journal Section | Articles |
Authors | |
Publication Date | March 31, 1964 |
Published in Issue | Year 1964 Volume: 17 Issue: 1 |