Normal Kabul Edilen Şahıslarda ve Habutuel Abortus Vak’alarında Listeria monocytogenes “O” Aglutinasyonları

Year 1967, Volume: 20 Issue: 3, 424 - 429, 30.09.1967

Hayati Ekmen

Abstract

This study evaluates the presence and titers of Listeria monocytogenes “O” agglutinating antibodies in two groups: 572 individuals presumed healthy and 91 women with histories of habitual abortion or stillbirth. Agglutination tests were performed using strains type I, III, 4a, and 4b at various serum dilutions. 59% of the normal group showed agglutinins up to a dilution of 1/200, while 3 sera from the abortion group presented higher titers (1/400–1/800), suggesting a potential role of Listeria monocytogenes, particularly type I, in some cases of habitual abortion. Though agglutination tests are limited by cross-reactivity, they may still be useful as supportive diagnostic tools.

Keywords

Listeria monocytogenes , habitual abortion , agglutinating antibodies , serological testing

Listeria “O” Agglutinating Antibodies in Normal Individuals and Habitual Abortus Cases

Abstract

Bu çalışmada, biri enfeksiyonla ilişkisi bilinmeyen 572 normal bireyden, diğeri bir veya daha fazla düşük/ölü doğum yapmış 91 kadından alınan serum örneklerinde Listeria monocytogenes “O” aglutininleri incelenmiştir. 1/200’e kadar olan titrelerde normal bireylerin %59’unda antikor saptanırken, abortus grubunda 3 serumda 1/400 ile 1/800 arasında yüksek titreli aglutinasyon gözlenmiştir. Bu sonuçlar Listeria monocytogenes’in —özellikle tip I suşunun— bazı abortus vakalarında rol oynayabileceğini düşündürmektedir. Aglutinasyon testleri kros reaksiyonlar nedeniyle sınırlı olsa da, tanıya yardımcı bir yöntem olabilir.

References

• 1 - Gray, M. L. and Killingen, A. H.: Listeria monocytogenes and listeric infections. Bact. Reviews 30: 309, 1966.
• 2 - Urbach, H. und Schabinski, G.: Zur Listeriose des Menschen. Z. Hyg. Infektions Krankheit 141: 239, 1955.
• 3 - Özbece, I. ve Doğuer, M.: Koyunlarda Listerialardan ileri gelen encephalomyelitis prulenta. Türk Veterinerler Cem. Derg. 7: 7, 1955.
• 4 - Doğuer, M.: Türkiye'de Listeriosis. Etlik Vet. Bakt. Enst. Dergisi 1: 345, 1961.
• 5 - Füzi, M. and Pillis, I.: Preparation of stable Listeria monocytogenes O antigen. J. Bact. 81: 155, 1961.
• 6 - Netter, E., Anzai, H., and Gorzyniski, E. A.: Identification of an antigen common to Listeria monocytogenes and other bacteria. Proc. Soc. Exp. Biol. Med. 10: 131, 1960.
• 7 - Welshimer, H. J.: Staphylococcal antibody production in response to injection with Listeria monocytogenes. J. Bact. 79: 456, 1960.
• 8 - Hood, M.: Listeriosis, report of 10 cases. Amer. J. Clin. Path. 28: 18, 1957.
• 9 - Osebold, J. W. and Sawyer, M. T.: Agglutinating antibodies for Listeria monocytogenes in human serum. J. Bact. 70: 350, 1955.
• 10 - King, E. O. and Seeliger, H. P. R.: Serological types of Listeria monocytogenes occurring in the United States. J. Bact. 77: 122, 1959.
• 11 - Gray, M. L., Singh, C., and Thorp, F. Jr.: Abortion, stillbirth, and early death in rabbits by L. monocytogenes via ocular instillation. Proc. Soc. Exp. Biol. Med. 89: 163, 1955.
• 12 - Gray, M. L., Singh, C., and Thorp, F. Jr.: Abortion, stillbirth, and early death in rabbits by L. monocytogenes via oral exposure. Proc. Soc. Exp. Biol. Med. 89: 169, 1955.
• 13 - Gray, M. L., Seeliger, H. P. R., and Potel, J.: Perinatal infection due to Listeria monocytogenes. Clin. Pediat. 2: 614, 1963.
• 14 - Rost, H. F., Paul, H., and Seeliger, H. P. R.: Habitual abortion and listeriosis. Deut. Med. Wochenschr. 83: 1893, 1958.
• 15 - Gray, M. L.: Genital listeriosis as a cause of repeated abortion. Lancet 2: 315, 1960.
• 16 - Rappaport, F., Rabinovitz, M., Toaff, R., and Krochik, N.: Genital listeriosis as a cause of repeated abortion. Lancet 1: 1273, 1960.