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Testosteron ve HCG'nin Androjenik Aktivite Üzerine Tesirleri

Year 1967, Volume: 20 Issue: 4, 539 - 551, 31.12.1967

Abstract

Biological and Physiological specialities of HCG and Testosteron propionat have been reviewed. 75 mature mice were used for this purpose. HCG and Testosteron propionat were injected for 21 days. The genital tract was examined as regards weight, Histology and Biochemistry. The results are presented in (tables 1, 2, 3) and (figures 1 abc, 2 abc, 3 abc). Some of the results confirm us, but some of them contradict on especially practice because of the changes they exhibit in histological structures.

This experiment has been performed in The Worcester Foundation for Experimental Biology Shrewsbury, Mass. U.S.A. in 1965. I wish to extend my thanks to the staff members of the WFEB.

This subject was presented at the Pharmacological Department on March, 15 1967.

Ethical Statement

-

Supporting Institution

Ankara University, Faculty of Medicine, Department of Urology

Project Number

-

Thanks

-

References

  • 1- KUPPERMAN HERBERTS: Human Endocrinology Vol. 1:3-27, Vol. 2: 504, 1963.
  • 2- HANCOCK J. L. : The Morphologic characteristics of spermatozoa and fertility. İnter. J. Fertil. 4: 347, 1959.
  • 3- MOORE R. C. : Experimental studies on the male reproductive system. J. Urol 65: 497, 1951.
  • 4- ROOSEN E. C., RUNGE: Rete testis in the albino rat; its structure, development and morphological significance, Acta. 45: 1, 1961.
  • 5- DAVİS E., Mc CUNE W. W..: Metabolism of human spermatozoa in semen Fertil and Steril. 1: 158, 1950.
  • 6- YAMAN L. S. : Viability of sperm in the male tract of rats. Acta Med. Turcica 3:34 1966.
  • 7- YAMAN L. S. : Parasempatik ilaçların seksüel hayat ejakülat terkibi ve spermatogenesis üzerine tesirleri Ank. Tıp Fak. Mec. Vol. 20. No. 1'e ilåveten supplementum 18, 1967.
  • 8- YOUNG W. C, CORNER G. W.: Sex internal Secretions 1: 336 1961.
  • 9- WEİSMAN A. I. : What to do and what not to do for infertile male. İnter. J. Fertil 7: 159­1962.
  • 10- WILLIAMS W. W.: Biochemistry of Semen Inter. J. Fertil. 4: 29, 1959.
  • 11- NELSON W. O. : Some problems of testicular function J. Urol. 69: 325, 1953.
  • 12- ENGLE E. T.: Physiology of testis J. Urol. 73: 544, 1955.
  • 13- HARRISON R. G. : Factors influencing the process of spermatogenesis in experimental animals. Brit. J. Urol. 28 422, 1956.
  • 14- THOMAS J. A., STRAUSS A. J. Jr. : The effect of steroids on mouse accessory fructose levels. Acta Endoc. 48 619, 1965.
  • 15- MANN T: Fructose and fructolysis in semen in relation to fertility the Lancet March 20 446, 1948.
  • 16- MANN, DAVIES HUMPREY: Fructose and citric acid assay in the secretions of the accessory glands of reproductive an indicator tests of the accessory glands of reproductive an indicator tests of male sex hormon activity. J. Endoc. 6: 75, 11949.
  • 17- ICHIKAWA T. WAKU M., KUMAMATO Y, ONODA T.: Spermatogenesis in eunuchoidism treated with androgen and gonadotropin. İnter. J. Fertil 4: 20, 1959.
  • 18- SWYER G. I.: Therapetic agents in defective spermatogenesis İnter J. Fertil. 4: 360, 1959.
  • 19- CULP O. S., BEYNON D. E.: Treatment of male infertility: An evaluation medicinal therapy. J. Urol. 63: 1093, 1950.
  • 20- MAC LEAD J.: Certain concepts in human male fertility J. Urol. 67: 19, 1952.
  • 21- CAMPBELL M: Urology Vol. 1, 133 W B. Saunders COMPANY Philadelphia and London 1953.
  • 22- CİBERT J. PERRİN J. : Urologie Chirurgicale 106, Edition Medicale flammarion, Paris 1958.
  • 23- COHEN M. R. Sterility and infertility: Medical views JAMA 168: 1963, 1958.
  • 24- DEVOS R.: Le traitment hormonal de la cryptorchidie Acta Urol. Belgica 29: 296, 1961.
  • 25- RUSSEL D. H. : Influence of small doses of stilbestrol on oligospermia J. Urol. 68: 775, 1952.
  • 26- TURLEY H. K., SHAW J. L. : Male Fertility: Review of 200 semen analysis and the use of pregnenolone therapy. J. Urol 77: 116, 1967.

The Effects of HCG and Testosteron Propionate on Androgenic Activity

Year 1967, Volume: 20 Issue: 4, 539 - 551, 31.12.1967

Abstract

Hipofiz ön fus hormonu ve androgenlerin Biolojik ve Fizyolojik özellikleri gözden geçirilmiştir. Ayrıca 75 laboratuar faresi üzerinde HCG ve testosteron tatbikatı 21 gün süre ile yapılmış ve genital organlar ağırlık, histolojik ve Bioşimik yönden tetkike tabi tutulmuştur. Alınan sonuçlar bize bir kısım klasik bilgileri teyid etmesine rağmen, kısmende bu ilaçların pratikte kullanılmasının bilhassa organda yaptığı histopatolojik değişiklikler sebebiyle her zaman uygun olmayacağını göstermiştir.
Bu tetkik 1955 yılında Amerika Birleşik Devletlerinde The Worcester Foundation for experimental Biology Shrewsbury Mass. da yapılmıştır. Müessese staff üyelerinin yakın ilgi ve yardımlarına bu vesile teşekkür etmeyi bir borç bilirim.

Ethical Statement

-

Supporting Institution

A.Ü. Tıp Fakültesi Üroloji Kliniği

Project Number

-

Thanks

-

References

  • 1- KUPPERMAN HERBERTS: Human Endocrinology Vol. 1:3-27, Vol. 2: 504, 1963.
  • 2- HANCOCK J. L. : The Morphologic characteristics of spermatozoa and fertility. İnter. J. Fertil. 4: 347, 1959.
  • 3- MOORE R. C. : Experimental studies on the male reproductive system. J. Urol 65: 497, 1951.
  • 4- ROOSEN E. C., RUNGE: Rete testis in the albino rat; its structure, development and morphological significance, Acta. 45: 1, 1961.
  • 5- DAVİS E., Mc CUNE W. W..: Metabolism of human spermatozoa in semen Fertil and Steril. 1: 158, 1950.
  • 6- YAMAN L. S. : Viability of sperm in the male tract of rats. Acta Med. Turcica 3:34 1966.
  • 7- YAMAN L. S. : Parasempatik ilaçların seksüel hayat ejakülat terkibi ve spermatogenesis üzerine tesirleri Ank. Tıp Fak. Mec. Vol. 20. No. 1'e ilåveten supplementum 18, 1967.
  • 8- YOUNG W. C, CORNER G. W.: Sex internal Secretions 1: 336 1961.
  • 9- WEİSMAN A. I. : What to do and what not to do for infertile male. İnter. J. Fertil 7: 159­1962.
  • 10- WILLIAMS W. W.: Biochemistry of Semen Inter. J. Fertil. 4: 29, 1959.
  • 11- NELSON W. O. : Some problems of testicular function J. Urol. 69: 325, 1953.
  • 12- ENGLE E. T.: Physiology of testis J. Urol. 73: 544, 1955.
  • 13- HARRISON R. G. : Factors influencing the process of spermatogenesis in experimental animals. Brit. J. Urol. 28 422, 1956.
  • 14- THOMAS J. A., STRAUSS A. J. Jr. : The effect of steroids on mouse accessory fructose levels. Acta Endoc. 48 619, 1965.
  • 15- MANN T: Fructose and fructolysis in semen in relation to fertility the Lancet March 20 446, 1948.
  • 16- MANN, DAVIES HUMPREY: Fructose and citric acid assay in the secretions of the accessory glands of reproductive an indicator tests of the accessory glands of reproductive an indicator tests of male sex hormon activity. J. Endoc. 6: 75, 11949.
  • 17- ICHIKAWA T. WAKU M., KUMAMATO Y, ONODA T.: Spermatogenesis in eunuchoidism treated with androgen and gonadotropin. İnter. J. Fertil 4: 20, 1959.
  • 18- SWYER G. I.: Therapetic agents in defective spermatogenesis İnter J. Fertil. 4: 360, 1959.
  • 19- CULP O. S., BEYNON D. E.: Treatment of male infertility: An evaluation medicinal therapy. J. Urol. 63: 1093, 1950.
  • 20- MAC LEAD J.: Certain concepts in human male fertility J. Urol. 67: 19, 1952.
  • 21- CAMPBELL M: Urology Vol. 1, 133 W B. Saunders COMPANY Philadelphia and London 1953.
  • 22- CİBERT J. PERRİN J. : Urologie Chirurgicale 106, Edition Medicale flammarion, Paris 1958.
  • 23- COHEN M. R. Sterility and infertility: Medical views JAMA 168: 1963, 1958.
  • 24- DEVOS R.: Le traitment hormonal de la cryptorchidie Acta Urol. Belgica 29: 296, 1961.
  • 25- RUSSEL D. H. : Influence of small doses of stilbestrol on oligospermia J. Urol. 68: 775, 1952.
  • 26- TURLEY H. K., SHAW J. L. : Male Fertility: Review of 200 semen analysis and the use of pregnenolone therapy. J. Urol 77: 116, 1967.
There are 26 citations in total.

Details

Primary Language English
Subjects Urology
Journal Section Articles
Authors

Lâtif Sezai Yaman This is me

Project Number -
Publication Date December 31, 1967
Published in Issue Year 1967 Volume: 20 Issue: 4

Cite

APA Yaman, L. S. (1967). Testosteron ve HCG’nin Androjenik Aktivite Üzerine Tesirleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 20(4), 539-551.
AMA Yaman LS. Testosteron ve HCG’nin Androjenik Aktivite Üzerine Tesirleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. December 1967;20(4):539-551.
Chicago Yaman, Lâtif Sezai. “Testosteron Ve HCG’nin Androjenik Aktivite Üzerine Tesirleri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 20, no. 4 (December 1967): 539-51.
EndNote Yaman LS (December 1, 1967) Testosteron ve HCG’nin Androjenik Aktivite Üzerine Tesirleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası 20 4 539–551.
IEEE L. S. Yaman, “Testosteron ve HCG’nin Androjenik Aktivite Üzerine Tesirleri”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 20, no. 4, pp. 539–551, 1967.
ISNAD Yaman, Lâtif Sezai. “Testosteron Ve HCG’nin Androjenik Aktivite Üzerine Tesirleri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 20/4 (December 1967), 539-551.
JAMA Yaman LS. Testosteron ve HCG’nin Androjenik Aktivite Üzerine Tesirleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1967;20:539–551.
MLA Yaman, Lâtif Sezai. “Testosteron Ve HCG’nin Androjenik Aktivite Üzerine Tesirleri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 20, no. 4, 1967, pp. 539-51.
Vancouver Yaman LS. Testosteron ve HCG’nin Androjenik Aktivite Üzerine Tesirleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1967;20(4):539-51.