Kronik Solunum Sistemi Hastalıklarında, Akut Solunum Sistemi İnfeksiyonlarında, Akciğer Kanser Olanlarda Ve Romatoid Artritlilerde Mycoplasma Yönünden Bir Araştırma.

Year 1972, Volume: 25 Issue: 3, 401 - 418, 30.09.1972

Gültekin Altay

Abstract

Kronik solunum sistemi hastalığı olanlarla, akut solunum sistemi infeksiyonu olanlarda kültür ve serolojik testlerle mycoplasma insidansı araştırıldı. Bulgular solunum sistemi şikayeti olma- yan diğer hastalardaki bulgular ile karşılaştırıldı. Kronik akciğer hastalığı olanlarda 446.1, akut solunum sistemi infeksiyonu olanlarda %9 7, solunum sistemi şikayeti olmayanlarda “6 1.7 oranında mycoplasma, izole edildi. İzole edilen mycoplasmaların M. Salivarium, M. Hominis tip 1, M. Pharyngis olduğu üreme önlenim testi, biyoşimik ve serolojik testlerle tesbit edildi. KBD ile kronik solu- num sistemi hastalığı olanlarda ç4 4.T, akut solunum sistemi infeksiyonu olanlarda 10.7, solunum sistemi şikayeti olmayanlarda So O oranında 1/20 ve üzerindeki titrelerde M. Pneumonia'ya karşı antikor bulundu. Hiç bir gurupta M. Hominis tipi, M. Salivarium, M. Pharyngis'e karşı kayda değer vaka ve titrede antikor tespit edilmedi. Soğuk aglütinasyon, kronik solunum sistemi hastalığı olanlar- da 463.5, akut solunum sistemi infeksiyonu olanlarda o 9.T, solunum sistemi şikayeti olmayanlarda (4 oranında 1/80 ve üstün- deki serum dilüsyonlarında müspet bulundu. 38 akciğer kanserli hastadaki serolojik sonuçlar, kronik solunum sistemi hastalığı olanlardaki bulgulara yakın bulundu. KBD ile 50 romatoid artritli hastaya ait serumlarda M. Arthritidis'e karşı antikor bulunmadı.

Keywords

Mikoplazma enfeksiyonları, İnsan solunum yolu, Otoimmün hastalıklar

A STUDY ON MYCOPLASMA IN CHRONIC RESPIRATORY SYSTEM DISEASES, ACUTE RESPIRATORY SYSTEM INFECTIONS, LUNG CANCER AND RHEUMATOID ARTHRITIS.

Abstract

The incidence of mycoplasmas in patients with chronic respiratory diseases and in those with acute respiratory infections was studied by means of culturing the sputums or throat washings, CF test and cold agglutination. The findings were compared with those obtained from patients with no respiratory complaints. Mycoplasma isolation rates in chronic lung diseases, acute respiratory infections and in the control group were 6.1 0, 1796, 1.7 Go respectively. Among the isolates there were several M. Salivarium, M. Pharyngis, and M. Hominis type 1 which were identified by Growth-Inhibition Test, and other biologic and serologic test ineluding FA staining. Complement fixing antibodies against M. Pneumonia in the titers of 1: 20 or greater were found in 4.7 per cent of the patients with chronic lung diseases, 10.7 per cent of those with acute respiratory infections and in none of the patients without respiratory complaints. There werent considerable antibodies against M. Hominis type 1, M. Salivarium, and M. Pharyngis in any groups of the patients. Cold agglutinins in the titers of 1:80 or greater were present in 3.5 per cent of the patients with chronic lung diseases, 9.7 per cent of the patients with acute respiratory infections, andin 4 per cent of those who had o respiratory illness. The serologic findings in 38 patients with lung CA have been found to be very close to those of patients with chronic respiratory diseases. Only one serum has been found to have complement fixing antibodies against M. Arthritidis in the titer of 1:10 among sera obtained from 50 patients with rheumatoid arthritis,

Keywords

Mycoplasma infections, Human respiratory tract, Autoimmune diseases

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