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Bitkiler ve İnsan Sağlığı Açısından Melatonin

Year 2018, Volume: 47 Issue: (Özel Sayı 2) 1. Uluslararası Tarım Kongresi, 248 - 253, 26.12.2018

Abstract

Bir çok canlı organizmalarda varlığı ispatlanan bir molekül olan melatonin (N-acetyl-5-methoxytryptamine), ilk olarak 1958 yılında sığır beyin üstü bezinden izole edilen bir indol amin olarak keşfedilmiştir. Bitkilerden sonra tek hücreliler, mantarlar, algler, hayvanlar gibi evrimsel yapıları bakımından birbirlerinden oldukça farklı organizmalarda da varlığı tespit edilmiştir. Bitkilerde melatonin daha çok bitki büyüme düzenleyici etkisi ve strese dayanım etkisi olarak ortaya çıkmaktadır. Kök büyümesi, sürgün gelişimi, apikal dormansi, çiçeklenme, yaşlanmayı geciktirme, ROS ve RNS giderme, yüksek antioksidan özelliği, enzim düzenleyici etkisi, IAA, ABA ve JA gibi birçok mekanizma üzerinde etkisi mevcuttur. Melatonin hormonunun, insan sağlığı ve tüketilen gıdalar ile doğrudan ilişkisi olduğu bilinmektedir. Triptofan içeriği yüksek bitkilerin tüketimi ile insan vücudunda melatonin sentezinin hızlandığı ve başta kanser olmak üzere birçok hastalığı önleyici veya durdurucu etkisi olduğu görülmektedir. Melatonin hormonunun asıl görevi, vücudun biyolojik saatini ve ritmini ayarlamaktır. Bu derlemede, fonksiyonel gıdalar, bitkiler ve insan sağlığı açısından melatoninin etkileri hakkında bilgi verilmesi amaçlanmıştır.

References

  • Afreen, F., Zobayed, S., Kozai, T., 2006. Melatonin in Glycyrrhiza uralensis: response of plant roots to spectral quality of light and UV-B radiation. Journal of Pineal Research 41, 108-115.
  • Anisimov, V.N., Popovich, I.G., Zabezhinski, M.A., Anisimov, S.V., Vesnushkin, G.M., Vinogradova, I.A., 2006. Melatonin as antioxidant, geroprotector and anticarcinogen. Biochim Biophys Acta 757:573-89.
  • Anonim, 2017-a. www.iyibilgi.com (Erişim: Mart 2018).
  • Anonim, 2017-b. https://groups.google.com/ forum/#!topic/eskisehir-tabip-odasi-turk-sanat-muzigi-korosu/q2azvtaneks (Erişim: Mart 2018).
  • Anonim, 2017-c. https://groups.google.com/ forum/#!topic/eskisehir-tabip-odasi-turk-sanat-muzigi-korosu/q2azvtaneks (Erişim: Mart 2018).
  • Anonim, 2017-d. http://www.doktorsitesi.com/ yazi/melatonin-hormonu/7544 (Erişim: Mart 2018).
  • Anonim, 2017-e. http://www.melatoninturkiye. com (Erişim:Mart 2018).
  • Arnao, M.B., Hernández-Ruiz, J., 2006. The physiological function of melatonin in plants. Plant Signaling and Behavior 1:89-95.
  • Arnao, M.B., Hernández-Ruiz, J., 2007. Melatonin promotes adventitiousand lateral root regeneration in etiolated hypocotyls of Lupinus albus L. Journal of Pineal Research 42:147-152.
  • Arnao, M.B., Hernández-Ruiz, J., 2014. Melatonin: plant growth regulator and/or biostimulator during stress? Trends Plant Sci. 19:789-797. 10.1016/j.tplants.2014.07.006 [PubMed] [Cross Ref].
  • Arnao, M.B., Hernandez-Ruiz, J., 2015. Functions of melatonin in plants: a review. Journal of Pineal Research, 59:133-150.
  • Bajwa, V.S., Shukla, M.R., Sherif, S.M., Murch, S.J., Saxena, P.K., 2014. Role of melatonin in alleviating cold stress in Arabidopsis thaliana. J. Pineal Res. 56:238-245. 10.1111/jpi.12115[PubMed] [Cross Ref]
  • Bartsch, C., Bartsch, H., 2006. The anti-tumor activity of pineal melatonin and cancer enhancing life styles in industrialized societies. Cancer Causes Control 17:559-71.
  • Chen, Q., Qi, W.B., Reiter, R.J., Wei, W., Wang, B.M., 2009. Exogenously applied melatonin stimulates root growth and raises endogenous indoleacetic acid in roots of etiolated seedlings of Brassica juncea. Journal of Plant Physiology 166:324-328.
  • Cipolla-Neto, J., Amaral, F.G., Afeche, S.C., Tan, D.X., Reiter, R.J., 2014. Melatonin, energy metabolism, and obesity: a review. Journal of Pineal Research 56:371-381.
  • Figueiro, M.G., Rea, M.S., Bullough, J.D., 2006. Does architectural lighting contribute to reast cancer? J. Carcinog 5:20.
  • Hansen, J., 2006. Risk of breast cancer after night-and shift work: current evidence and ongoing studies in Denmark. Cancer Causes Control 17:531-37.
  • Hernández-Ruiz, J., Cano, A., Arnao, M.B., 2004. Melatonin: a growthstimulating compound present in lupin tissues. Planta 220:140-144.
  • Hernández-Ruiz, J., Cano, A., Arnao, M.B., 2005. Melatonin acts as a growth-stimulating compound in some monocot species. Journal of Pineal Research 39:137-142.
  • Hernández-Ruiz, J., Arnao, M.B., 2008. Melatonin stimulates the expansion of etiolated lupin cotyledons. Plant Growth Regulation 55:29-34.
  • Janas, K.M., Posmyk, M.M., 2013. Melatonin, an underestimated natural substance with great potential for agricultural application. Acta Physiol. Plant 35:285-3292. 10.1007/ s11738-013-1372-0 [Cross Ref].
  • Jung, B., Ahmad, N., 2006. Melatonin in cancer management: progress and promise. Cancer Res 66:9789-93.
  • Kolar, J., Johnson, C., Machackova, I., 2003. Exogenously applied melatonin (N-acetyl-5-methoxytryptamine) affects flowering of the shortday plant Chenopodium rubrum. Physiologia Plantarum 118:605-612.
  • Kołodziejczyk, I., Posmyk, M.M., 2016. Melatonin-a new plant biostimulator? J. Elem. 21:1187-1198. 10.5601/jelem.2015.20. 3.1012 [Cross Ref].
  • Korkmaz, A., Reiter, R.J., Topal, T., Manchester, L.C., Oter, S., Tan, D.X., 2009. Melatonin: an established antioxidant worthy of use in clinical trials. Mol. Med. 15:43-50.
  • Korkmaz, A., Değer, Ö., Cuci, Y., 2014. Profiling the melatonin content in organs of the pepper plant during different growth stages. Scientia Horticulturae, 172:242-247.
  • Korkmaz, A., Karaca, A., Kocaçınar, F., Cuci, Y., 2016. The effects of seed treatment with melatonin on germination and emergence performance of pepper seeds under chilling stress. Tarım Bilimleri Dergisi/Journal of Agricultural Sciences, (in press).
  • Lerner, A.B., Case, J.D., Takahashi, Y., 1958. Isolation of melatonin, a pineal factor that lightness melanocytes. Journal of American Chemical Society, 80:2587-2591.
  • Li, C., Wang, P., Wei, Z., Liang, D., Liu, C., Yin, L., Jia, D., Fu, M., Ma, F., 2012. The mitigation effects of exogenous melatonin on salinity-induced stress in Malus hupehensis. Journal of Pineal Research 53:298-306.
  • Meng, J.F., Xu, T.F., Wang, Z.Z., Fang, Y.L., Xi, Z.M., Zhang, Z.W., 2014. The ameliorative effects of exogenous melatonin on grape cuttings under water-deficient stress: antioxidant metabolites, leaf anatomy, and chloroplast morphology. J. Pineal Res. 57:200-212. 10.1111/jpi.12159 [PubMed] [Cross Ref].
  • Reiter, R.J., Tan, D.X., Burkhardt, S., Manchester, L.C., 2001. Melatonin in plants. Nutrition Reviews, 59:286-290.
  • Reiter, R.J., 2004 Mechanisms of cancer inhibition by melatonin. J. Pineal Res 37:213-14.
  • Reiter, R.J., Gultekin, F., Flores, L.J., Terron, M.P., Tan, D.X., 2006. Melatonin: toplum sağlığını geliştirmek için potansiyel kullanımı. TSK Koruyucu Hekimlik Bülteni 5:131-58.
  • Reiter, R.J., Tan, D.X., Fuentes-Broto, L., 2010. Melatonin: a multitasking molecule. Progress in Brain Research 181, 127-151.
  • Reiter, R.J., Tan, D.X., Zhou, Z., Cruz, M.H.C., Fuentes-Broto, L., Galano, A., 2015. Phytomelatonin: assisting plants to survive and thrive. Molecules, 20: 7396-7437.
  • Sarropoulou, V.N., Dimassi-Theriou, K., Therios, I., Koukourikou-Petridou, M., 2012a. Melatonin enhances root regeneration, photosynthetic pigments, biomass, total carbohydrates and proline content in the cherry rootstock PHL-C (Prunus avium × Prunus cerasus). Plant Physiology and Biochemistry 61:162-168.
  • Sarrou, E., Therios, I., Dimassi-Theriou, K., 2014. Melatonin and other factors that promote rooting and sprouting of shoot cuttings in Punica granatum cv. Wonderful. Turkish Journal of Botany 38:293-301.
  • Shi, H., Jiang, C., Ye, T., Tan, D.X., Reiter, R.J., Zhang, H., Liu, R., Chan, Z., 2015. Comparative physiological, metabolomic, and transcriptomic analyses reveal mechanisms of ımproved abiotic stress resistance in bermudagrass Cynodon dactylon L. Pers. by Exogenous Melatonin. Journal of Experimental Botany, 66:681-694.
  • Shida, C., Castrucci, A., Lamyfreund, M., 1994. High melatonin solubility in aqueous-medium. Journal of Pineal Research 16:198-201.
  • Tan, D.X., Manchester, L.C., Di Mascio, P., Martinez, G.R., Prado, F.M., Reiter, R.J., 2007-a. Novel rhythms of N-1-acetyl-N-2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation. FASEB Journal 21:1724-1729.
  • Tan, D.X., Manchester, L.C., Helton, P., Reiter, R.J., 2007-b. Phytoremediative capacity of plants enriched with melatonin. Plant Signaling and Behavior, 2:514-516.
  • Tettamanti, C., Cerabolini, B., Gerola, P., Conti, A. 2000., Melatonin identification in medicinal plants. Acta Phytotherapeutica, 3:137-144.
  • Vriend, J., Reiter, R.J., 2015. Melatonin feedback on clock genes: a theory involving the proteasome. J. Pineal Res. 58:1-11. 10.1111/jpi.12189 [PubMed] [Cross Ref].
  • Weeda, S., Zhang, N., Zhao, X., Ndip, G., Guo, Y., Buck, G.A., Fu, C., Ren, S.X., 2014. Arabidopsis transcriptome analysis reveals key roles of melatonin in plant defense systems. PLoS One 9, e93462-e93462.
  • Xu, X.D., 2010. Effects of exogenous melatonin on physiological response of cucumber seedlings under high temperature stress. Thesis for Master’s Degree, Northwest A&F University, Yangling Shanxi, China.
  • Zhang, N., Zhao, B., Zhang, H.J., Weeda, S., Yang, C., Yang, Z.C., Ren, S.X., Guo, Y.D. 2013. Melatonin promotes water-stress tolerance, lateral root formation, and seed germination in cucumber (Cucumis sativus L.). Journal of Pineal Research 54:15-23.
  • Zhang, N., Zhang, H.J., Zhao, B. et al., 2014., The RNA-seq approach to discriminate gene expression profiles in response to melatonin on cucumber lateral root formation. Journal of Pineal Research 56:39-50.
  • Zhang, N., Sun, Q., Zhang, H., Cao, Y., Weeda, S., Ren, S., Guo, Y.D., 2015. Roles of melatonin in abiotic stress resistance in plants. Journal of Experimental Botany, 66:647-656.

Melatonine For Plants and Human Health

Year 2018, Volume: 47 Issue: (Özel Sayı 2) 1. Uluslararası Tarım Kongresi, 248 - 253, 26.12.2018

Abstract

Melatonin (N-acetyl-5-methoxytryptamine), a molecule that has been proven in many living organisms, was first discovered in 1958 as an indole amine isolated from the bovine superficial gland. After the plants, single cells, fungi, algae, animals, etc. have been found in organisms quite different from each other in terms of evolutionary structures. In plants, melatonin emerges as plant growth regulatory effect and strase resistance effect. There are effects on many mechanisms such as root growth, shoot growth, apical dormancy, flowering, delayed aging, ROS and RNS removal, high antioxidant properties, enzyme regulatory effect, IAA, ABA and JA. Melatonin hormone is known to be directly related to human health and consumed foods. The content of tryptophan seems to be accelerated by the synthesis of melatonin in the human body with the consumption of high plants, and it is the preventive or stopping effect of many diseases, especially cancer. The main task of the melatonin hormone is to adjust the body's biological clock and rhythm. In this review, it is aimed to give information about the effects of melatonin in terms of functional foods, plants and human health.

References

  • Afreen, F., Zobayed, S., Kozai, T., 2006. Melatonin in Glycyrrhiza uralensis: response of plant roots to spectral quality of light and UV-B radiation. Journal of Pineal Research 41, 108-115.
  • Anisimov, V.N., Popovich, I.G., Zabezhinski, M.A., Anisimov, S.V., Vesnushkin, G.M., Vinogradova, I.A., 2006. Melatonin as antioxidant, geroprotector and anticarcinogen. Biochim Biophys Acta 757:573-89.
  • Anonim, 2017-a. www.iyibilgi.com (Erişim: Mart 2018).
  • Anonim, 2017-b. https://groups.google.com/ forum/#!topic/eskisehir-tabip-odasi-turk-sanat-muzigi-korosu/q2azvtaneks (Erişim: Mart 2018).
  • Anonim, 2017-c. https://groups.google.com/ forum/#!topic/eskisehir-tabip-odasi-turk-sanat-muzigi-korosu/q2azvtaneks (Erişim: Mart 2018).
  • Anonim, 2017-d. http://www.doktorsitesi.com/ yazi/melatonin-hormonu/7544 (Erişim: Mart 2018).
  • Anonim, 2017-e. http://www.melatoninturkiye. com (Erişim:Mart 2018).
  • Arnao, M.B., Hernández-Ruiz, J., 2006. The physiological function of melatonin in plants. Plant Signaling and Behavior 1:89-95.
  • Arnao, M.B., Hernández-Ruiz, J., 2007. Melatonin promotes adventitiousand lateral root regeneration in etiolated hypocotyls of Lupinus albus L. Journal of Pineal Research 42:147-152.
  • Arnao, M.B., Hernández-Ruiz, J., 2014. Melatonin: plant growth regulator and/or biostimulator during stress? Trends Plant Sci. 19:789-797. 10.1016/j.tplants.2014.07.006 [PubMed] [Cross Ref].
  • Arnao, M.B., Hernandez-Ruiz, J., 2015. Functions of melatonin in plants: a review. Journal of Pineal Research, 59:133-150.
  • Bajwa, V.S., Shukla, M.R., Sherif, S.M., Murch, S.J., Saxena, P.K., 2014. Role of melatonin in alleviating cold stress in Arabidopsis thaliana. J. Pineal Res. 56:238-245. 10.1111/jpi.12115[PubMed] [Cross Ref]
  • Bartsch, C., Bartsch, H., 2006. The anti-tumor activity of pineal melatonin and cancer enhancing life styles in industrialized societies. Cancer Causes Control 17:559-71.
  • Chen, Q., Qi, W.B., Reiter, R.J., Wei, W., Wang, B.M., 2009. Exogenously applied melatonin stimulates root growth and raises endogenous indoleacetic acid in roots of etiolated seedlings of Brassica juncea. Journal of Plant Physiology 166:324-328.
  • Cipolla-Neto, J., Amaral, F.G., Afeche, S.C., Tan, D.X., Reiter, R.J., 2014. Melatonin, energy metabolism, and obesity: a review. Journal of Pineal Research 56:371-381.
  • Figueiro, M.G., Rea, M.S., Bullough, J.D., 2006. Does architectural lighting contribute to reast cancer? J. Carcinog 5:20.
  • Hansen, J., 2006. Risk of breast cancer after night-and shift work: current evidence and ongoing studies in Denmark. Cancer Causes Control 17:531-37.
  • Hernández-Ruiz, J., Cano, A., Arnao, M.B., 2004. Melatonin: a growthstimulating compound present in lupin tissues. Planta 220:140-144.
  • Hernández-Ruiz, J., Cano, A., Arnao, M.B., 2005. Melatonin acts as a growth-stimulating compound in some monocot species. Journal of Pineal Research 39:137-142.
  • Hernández-Ruiz, J., Arnao, M.B., 2008. Melatonin stimulates the expansion of etiolated lupin cotyledons. Plant Growth Regulation 55:29-34.
  • Janas, K.M., Posmyk, M.M., 2013. Melatonin, an underestimated natural substance with great potential for agricultural application. Acta Physiol. Plant 35:285-3292. 10.1007/ s11738-013-1372-0 [Cross Ref].
  • Jung, B., Ahmad, N., 2006. Melatonin in cancer management: progress and promise. Cancer Res 66:9789-93.
  • Kolar, J., Johnson, C., Machackova, I., 2003. Exogenously applied melatonin (N-acetyl-5-methoxytryptamine) affects flowering of the shortday plant Chenopodium rubrum. Physiologia Plantarum 118:605-612.
  • Kołodziejczyk, I., Posmyk, M.M., 2016. Melatonin-a new plant biostimulator? J. Elem. 21:1187-1198. 10.5601/jelem.2015.20. 3.1012 [Cross Ref].
  • Korkmaz, A., Reiter, R.J., Topal, T., Manchester, L.C., Oter, S., Tan, D.X., 2009. Melatonin: an established antioxidant worthy of use in clinical trials. Mol. Med. 15:43-50.
  • Korkmaz, A., Değer, Ö., Cuci, Y., 2014. Profiling the melatonin content in organs of the pepper plant during different growth stages. Scientia Horticulturae, 172:242-247.
  • Korkmaz, A., Karaca, A., Kocaçınar, F., Cuci, Y., 2016. The effects of seed treatment with melatonin on germination and emergence performance of pepper seeds under chilling stress. Tarım Bilimleri Dergisi/Journal of Agricultural Sciences, (in press).
  • Lerner, A.B., Case, J.D., Takahashi, Y., 1958. Isolation of melatonin, a pineal factor that lightness melanocytes. Journal of American Chemical Society, 80:2587-2591.
  • Li, C., Wang, P., Wei, Z., Liang, D., Liu, C., Yin, L., Jia, D., Fu, M., Ma, F., 2012. The mitigation effects of exogenous melatonin on salinity-induced stress in Malus hupehensis. Journal of Pineal Research 53:298-306.
  • Meng, J.F., Xu, T.F., Wang, Z.Z., Fang, Y.L., Xi, Z.M., Zhang, Z.W., 2014. The ameliorative effects of exogenous melatonin on grape cuttings under water-deficient stress: antioxidant metabolites, leaf anatomy, and chloroplast morphology. J. Pineal Res. 57:200-212. 10.1111/jpi.12159 [PubMed] [Cross Ref].
  • Reiter, R.J., Tan, D.X., Burkhardt, S., Manchester, L.C., 2001. Melatonin in plants. Nutrition Reviews, 59:286-290.
  • Reiter, R.J., 2004 Mechanisms of cancer inhibition by melatonin. J. Pineal Res 37:213-14.
  • Reiter, R.J., Gultekin, F., Flores, L.J., Terron, M.P., Tan, D.X., 2006. Melatonin: toplum sağlığını geliştirmek için potansiyel kullanımı. TSK Koruyucu Hekimlik Bülteni 5:131-58.
  • Reiter, R.J., Tan, D.X., Fuentes-Broto, L., 2010. Melatonin: a multitasking molecule. Progress in Brain Research 181, 127-151.
  • Reiter, R.J., Tan, D.X., Zhou, Z., Cruz, M.H.C., Fuentes-Broto, L., Galano, A., 2015. Phytomelatonin: assisting plants to survive and thrive. Molecules, 20: 7396-7437.
  • Sarropoulou, V.N., Dimassi-Theriou, K., Therios, I., Koukourikou-Petridou, M., 2012a. Melatonin enhances root regeneration, photosynthetic pigments, biomass, total carbohydrates and proline content in the cherry rootstock PHL-C (Prunus avium × Prunus cerasus). Plant Physiology and Biochemistry 61:162-168.
  • Sarrou, E., Therios, I., Dimassi-Theriou, K., 2014. Melatonin and other factors that promote rooting and sprouting of shoot cuttings in Punica granatum cv. Wonderful. Turkish Journal of Botany 38:293-301.
  • Shi, H., Jiang, C., Ye, T., Tan, D.X., Reiter, R.J., Zhang, H., Liu, R., Chan, Z., 2015. Comparative physiological, metabolomic, and transcriptomic analyses reveal mechanisms of ımproved abiotic stress resistance in bermudagrass Cynodon dactylon L. Pers. by Exogenous Melatonin. Journal of Experimental Botany, 66:681-694.
  • Shida, C., Castrucci, A., Lamyfreund, M., 1994. High melatonin solubility in aqueous-medium. Journal of Pineal Research 16:198-201.
  • Tan, D.X., Manchester, L.C., Di Mascio, P., Martinez, G.R., Prado, F.M., Reiter, R.J., 2007-a. Novel rhythms of N-1-acetyl-N-2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation. FASEB Journal 21:1724-1729.
  • Tan, D.X., Manchester, L.C., Helton, P., Reiter, R.J., 2007-b. Phytoremediative capacity of plants enriched with melatonin. Plant Signaling and Behavior, 2:514-516.
  • Tettamanti, C., Cerabolini, B., Gerola, P., Conti, A. 2000., Melatonin identification in medicinal plants. Acta Phytotherapeutica, 3:137-144.
  • Vriend, J., Reiter, R.J., 2015. Melatonin feedback on clock genes: a theory involving the proteasome. J. Pineal Res. 58:1-11. 10.1111/jpi.12189 [PubMed] [Cross Ref].
  • Weeda, S., Zhang, N., Zhao, X., Ndip, G., Guo, Y., Buck, G.A., Fu, C., Ren, S.X., 2014. Arabidopsis transcriptome analysis reveals key roles of melatonin in plant defense systems. PLoS One 9, e93462-e93462.
  • Xu, X.D., 2010. Effects of exogenous melatonin on physiological response of cucumber seedlings under high temperature stress. Thesis for Master’s Degree, Northwest A&F University, Yangling Shanxi, China.
  • Zhang, N., Zhao, B., Zhang, H.J., Weeda, S., Yang, C., Yang, Z.C., Ren, S.X., Guo, Y.D. 2013. Melatonin promotes water-stress tolerance, lateral root formation, and seed germination in cucumber (Cucumis sativus L.). Journal of Pineal Research 54:15-23.
  • Zhang, N., Zhang, H.J., Zhao, B. et al., 2014., The RNA-seq approach to discriminate gene expression profiles in response to melatonin on cucumber lateral root formation. Journal of Pineal Research 56:39-50.
  • Zhang, N., Sun, Q., Zhang, H., Cao, Y., Weeda, S., Ren, S., Guo, Y.D., 2015. Roles of melatonin in abiotic stress resistance in plants. Journal of Experimental Botany, 66:647-656.
There are 48 citations in total.

Details

Primary Language Turkish
Subjects Agricultural Engineering (Other)
Journal Section Makaleler
Authors

Akgül Taş

Selma Kuru Berk

Selma Tuna Koçoğlu

Muttalip Gündoğdu

Publication Date December 26, 2018
Submission Date July 2, 2018
Acceptance Date December 3, 2018
Published in Issue Year 2018 Volume: 47 Issue: (Özel Sayı 2) 1. Uluslararası Tarım Kongresi

Cite

APA Taş, A., Kuru Berk, S., Tuna Koçoğlu, S., Gündoğdu, M. (2018). Bitkiler ve İnsan Sağlığı Açısından Melatonin. Bahçe, 47((Özel Sayı 2) 1. Uluslararası Tarım Kongresi), 248-253.
AMA Taş A, Kuru Berk S, Tuna Koçoğlu S, Gündoğdu M. Bitkiler ve İnsan Sağlığı Açısından Melatonin. Bahçe. December 2018;47((Özel Sayı 2) 1. Uluslararası Tarım Kongresi):248-253.
Chicago Taş, Akgül, Selma Kuru Berk, Selma Tuna Koçoğlu, and Muttalip Gündoğdu. “Bitkiler Ve İnsan Sağlığı Açısından Melatonin”. Bahçe 47, no. (Özel Sayı 2) 1. Uluslararası Tarım Kongresi (December 2018): 248-53.
EndNote Taş A, Kuru Berk S, Tuna Koçoğlu S, Gündoğdu M (December 1, 2018) Bitkiler ve İnsan Sağlığı Açısından Melatonin. Bahçe 47 (Özel Sayı 2) 1. Uluslararası Tarım Kongresi 248–253.
IEEE A. Taş, S. Kuru Berk, S. Tuna Koçoğlu, and M. Gündoğdu, “Bitkiler ve İnsan Sağlığı Açısından Melatonin”, Bahçe, vol. 47, no. (Özel Sayı 2) 1. Uluslararası Tarım Kongresi, pp. 248–253, 2018.
ISNAD Taş, Akgül et al. “Bitkiler Ve İnsan Sağlığı Açısından Melatonin”. Bahçe 47/(Özel Sayı 2) 1. Uluslararası Tarım Kongresi (December2018), 248-253.
JAMA Taş A, Kuru Berk S, Tuna Koçoğlu S, Gündoğdu M. Bitkiler ve İnsan Sağlığı Açısından Melatonin. Bahçe. 2018;47:248–253.
MLA Taş, Akgül et al. “Bitkiler Ve İnsan Sağlığı Açısından Melatonin”. Bahçe, vol. 47, no. (Özel Sayı 2) 1. Uluslararası Tarım Kongresi, 2018, pp. 248-53.
Vancouver Taş A, Kuru Berk S, Tuna Koçoğlu S, Gündoğdu M. Bitkiler ve İnsan Sağlığı Açısından Melatonin. Bahçe. 2018;47((Özel Sayı 2) 1. Uluslararası Tarım Kongresi):248-53.

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