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CHRONIC BLADDER PAIN MANAGEMENT AND QUALITY OF LIFE

Year 2025, Volume: 4 Issue: 2, 67 - 77, 10.11.2025
https://doi.org/10.61830/balkansbd.1770090

Abstract

Among urinary system diseases, chronic bladder pain has negative effects on quality of life; the duration and severity of symptoms, individuals' withdrawal from social life, and compliance with treatment require care management. Although its etiology is not fully understood, it includes urological pain conditions such as interstitial cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome. The diagnosis and treatment process varies depending on the individual. Today, various pharmacological and non-pharmacological methods are available as treatment options. Determining the effects of symptoms and treatment applications on the individual's quality of life plays an important role in care management. Applications aimed at improving the individual's quality of life should be planned. In this review, the definition, pathophysiology, diagnostic methods, and effects on quality of life of chronic bladder pain are summarized in accordance with current guidelines, publications, and evidence-based recommendations.

References

  • 1. Birder LA. Pathophysiology of interstitial cystitis. Int J Urol. 2019;26:12-5.
  • 2. Clemens JQ, Erickson DR, Varela NP, Lai HH. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome. J Urol. 2022;208(1):34-42.
  • 3. Mertoğlu O, Budak S, Yücel C, Kısa E, Kocaoğlu Z. İnterstisyel Sistit/Ağrılı Mesane Sendromunda Tedavi Yönetimi. Jinekoloji- Obstet Ve Neonatoloji Tıp Derg. 2018;15(2):66- 9.
  • 4. Enaux J, Sorber M, Kaiser AV, Knecht C. Women’s Illness Experience With Interstitial Cystitis/Bladder Pain Syndrome: A Scoping Review. Int J Urol Nurs. 2025;19(2):e70020.
  • 5. Cox A. Management of interstitial cystitis/bladder pain syndrome. Can Urol Assoc J. 2018;12(6 Suppl 3):S157.
  • 6. Cox A, Golda N, Nadeau G, Nickel JC, Carr L, Corcos J, vd. CUA guideline: Diagnosis and treatment of interstitial cystitis/bladder pain syndrome. Can Urol Assoc J. 2016;10(5- 6):E136.
  • 7. Hanno P. Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome. Letter. J Urol. 2022;208(6):1178.
  • 8. Colemeadow J, Sahai A, Malde S. Clinical management of bladder pain syndrome/interstitial cystitis: a review on current recommendations and emerging treatment options. Res Rep Urol. 2020;331-43. 9. Almutairi S. Prevalence of Symptoms of Bladder Pain Syndrome/Interstitial Cystitis Among Adult Females in the Saudi Arabia. J Pioneer Med Sci. 2024;13:126-32.
  • 10. IC-MAS.pdf [İnternet]. [a.yer 21 Ağustos 2025]. Erişim adresi: https://kontinansdernegi.org/wpcontent/ uploads/2021/12/IC-MAS.pdf
  • 11. Tolle J, Kaftan B, Bschleipfer T. S2k-Leitlinie Diagnostik und Therapie der interstitiellen Zystitis (IC/BPS). J Für Urol UrogynäkologieÖsterreich. 2022;29(3):94-101.
  • 12. Lim Y, Leslie SW, O’Rourke S. Interstitial cystitis/bladder pain syndrome. İçinde: StatPearls [Internet] [İnternet]. StatPearls Publishing; 2024 [a.yer 21 Ağustos 2025]. Erişim adresi: https://www.ncbi.nlm.nih.gov/sites/books/NB K570588/
  • 13. Lovick TA. Central control of visceral pain and urinary tract function. Auton Neurosci. 2016;200:35-42.
  • 14. Khullar V, Digesu GA, Veit‐Rubin N, Sahai A, Rahnama’i MS, Tarcan T, vd. How can we improve the diagnosis and management of bladder pain syndrome? Part 2:ICI‐RS 2018. Neurourol Urodyn [Internet]. Aralık 2019 [a.yer 21 Ağustos 2025];38(S5). Erişim adresi: https://onlinelibrary.wiley.com/doi/10.1002/na u.24245
  • 15. Mottet N, Cornford P, Van den Bergh RCN, Briers E, De Santis M, Fanti S, vd. EAU guidelines. Edn. presented at the EAU Annual Congress Amsterdam. Eur Urol. 2022;
  • 16. Malde S, Palmisani S, Al‐Kaisy A, Sahai A. Guideline of guidelines: bladder pain syndrome. BJU Int. Kasım 2018;122(5):729-43.
  • 17. Daniels AM, Schulte AR, Herndon CM. Interstitial cystitis: an update on the disease process and treatment. J Pain Palliat Care Pharmacother. 2018;32(1):49-58.
  • 18. Santos TG dos, Miranda IAS de, Nygaard CC, Schreiner L, Castro R de A, Haddad JM. Systematic Review of Oral Therapy for the Treatment of Symptoms of Bladder PainSyndrome: The Brazilian Guidelines. Rev Bras Ginecol E Obstetrícia. 2018;40:96-102.
  • 19. Elhossieny NA, Barakat N, Abdel-maboud M. Interstitial Cystitis Syndrome: Pathophysiology, Causes, and Management Approaches. Zagazig Vet J. 2025;53(2):108-25.
  • 20. Imamura M, Scott NW, Wallace SA, Ogah JA, Ford AA, Dubos YA, vd. Interventions for treating people with symptoms of bladder pain syndrome: a network meta-analysis. Cochrane Database Syst Rev [İnternet]. 2020 [a.yer 21 Ağustos 2025];(7). Erişim adresi: https://www.cochranelibrary.com/cdsr/doi/10.1 002/14651858.CD013325.pub2/abstract
  • 21. Vasudevan V, Moldwin R. Addressing quality of life in the patient with interstitial cystitis/bladder pain syndrome. Asian J Urol. 2016;4(1):50.
  • 22. Ginkel C van, Martens F, Scholtes M, Heesakkers J, Janssen DA. Quality of life and treatment modalities in patients with interstitial cystitis: the patients’ perspective. İçinde: Healthcare [İnternet]. MDPI; 2024 [a.yer 21 Ağustos 2025]. s. 466. Erişim adresi: https://www.mdpi.com/2227-9032/12/4/466
  • 23. Jia X, Crouss T, Rana N, Whitmore KE. Complementary and Alternative Medicine for the Management of Interstitial Cystitis/Bladder Pain Syndrome: a Recent Update. Curr Bladder Dysfunct Rep. Eylül 2020;15(3):214-8.

Kronik Mesane Ağrısı Yönetimi ve Yaşam Kalitesi

Year 2025, Volume: 4 Issue: 2, 67 - 77, 10.11.2025
https://doi.org/10.61830/balkansbd.1770090

Abstract

Üriner sistem hastalıkları arasında yaşam kalitesi açısından olumsuz etkileri olan kronik mesane ağrısı; semptomların süresi, şiddeti, bireylerin sosyal yaşantıdan uzaklaşması, tedavi sürecine uyum sağlama açısından bakım yönetimi gerektirmektedir. Etiyolojisi tam olarak bilinmemekle beraber, interstisyel sistit/mesane ağrısı sendromu ve kronik prostatit/kronik pelvik ağrı sendromu gibi ürolojik ağrı durumlarını da içinde barındırmaktadır. Bireye özgü olarak tanı ve tedavi süreci değişkenlik göstermektedir. Günümüzde çeşitli farmakolojik ve nonfarmakolojik yöntemler tedavi seçenekleri arasındadır. Semptomlar ve tedavi uygulamalarının bireyin yaşam kalitesine etkilerini belirlemek bakımın yönetiminde önemli bir yere sahiptir. Bireye özgü olarak yaşam kalitesini arttırmaya yönelik uygulamalar planlanmalıdır. Bu derlemede, güncel kılavuzlar, yayınlar ve kanıta dayalı öneriler doğrultusunda kronik mesane ağrısının tanımlanması, fizyopatolojisi, tanı yöntemleri ve yaşam kalitesine etkileri özetlenmiştir.

References

  • 1. Birder LA. Pathophysiology of interstitial cystitis. Int J Urol. 2019;26:12-5.
  • 2. Clemens JQ, Erickson DR, Varela NP, Lai HH. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome. J Urol. 2022;208(1):34-42.
  • 3. Mertoğlu O, Budak S, Yücel C, Kısa E, Kocaoğlu Z. İnterstisyel Sistit/Ağrılı Mesane Sendromunda Tedavi Yönetimi. Jinekoloji- Obstet Ve Neonatoloji Tıp Derg. 2018;15(2):66- 9.
  • 4. Enaux J, Sorber M, Kaiser AV, Knecht C. Women’s Illness Experience With Interstitial Cystitis/Bladder Pain Syndrome: A Scoping Review. Int J Urol Nurs. 2025;19(2):e70020.
  • 5. Cox A. Management of interstitial cystitis/bladder pain syndrome. Can Urol Assoc J. 2018;12(6 Suppl 3):S157.
  • 6. Cox A, Golda N, Nadeau G, Nickel JC, Carr L, Corcos J, vd. CUA guideline: Diagnosis and treatment of interstitial cystitis/bladder pain syndrome. Can Urol Assoc J. 2016;10(5- 6):E136.
  • 7. Hanno P. Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome. Letter. J Urol. 2022;208(6):1178.
  • 8. Colemeadow J, Sahai A, Malde S. Clinical management of bladder pain syndrome/interstitial cystitis: a review on current recommendations and emerging treatment options. Res Rep Urol. 2020;331-43. 9. Almutairi S. Prevalence of Symptoms of Bladder Pain Syndrome/Interstitial Cystitis Among Adult Females in the Saudi Arabia. J Pioneer Med Sci. 2024;13:126-32.
  • 10. IC-MAS.pdf [İnternet]. [a.yer 21 Ağustos 2025]. Erişim adresi: https://kontinansdernegi.org/wpcontent/ uploads/2021/12/IC-MAS.pdf
  • 11. Tolle J, Kaftan B, Bschleipfer T. S2k-Leitlinie Diagnostik und Therapie der interstitiellen Zystitis (IC/BPS). J Für Urol UrogynäkologieÖsterreich. 2022;29(3):94-101.
  • 12. Lim Y, Leslie SW, O’Rourke S. Interstitial cystitis/bladder pain syndrome. İçinde: StatPearls [Internet] [İnternet]. StatPearls Publishing; 2024 [a.yer 21 Ağustos 2025]. Erişim adresi: https://www.ncbi.nlm.nih.gov/sites/books/NB K570588/
  • 13. Lovick TA. Central control of visceral pain and urinary tract function. Auton Neurosci. 2016;200:35-42.
  • 14. Khullar V, Digesu GA, Veit‐Rubin N, Sahai A, Rahnama’i MS, Tarcan T, vd. How can we improve the diagnosis and management of bladder pain syndrome? Part 2:ICI‐RS 2018. Neurourol Urodyn [Internet]. Aralık 2019 [a.yer 21 Ağustos 2025];38(S5). Erişim adresi: https://onlinelibrary.wiley.com/doi/10.1002/na u.24245
  • 15. Mottet N, Cornford P, Van den Bergh RCN, Briers E, De Santis M, Fanti S, vd. EAU guidelines. Edn. presented at the EAU Annual Congress Amsterdam. Eur Urol. 2022;
  • 16. Malde S, Palmisani S, Al‐Kaisy A, Sahai A. Guideline of guidelines: bladder pain syndrome. BJU Int. Kasım 2018;122(5):729-43.
  • 17. Daniels AM, Schulte AR, Herndon CM. Interstitial cystitis: an update on the disease process and treatment. J Pain Palliat Care Pharmacother. 2018;32(1):49-58.
  • 18. Santos TG dos, Miranda IAS de, Nygaard CC, Schreiner L, Castro R de A, Haddad JM. Systematic Review of Oral Therapy for the Treatment of Symptoms of Bladder PainSyndrome: The Brazilian Guidelines. Rev Bras Ginecol E Obstetrícia. 2018;40:96-102.
  • 19. Elhossieny NA, Barakat N, Abdel-maboud M. Interstitial Cystitis Syndrome: Pathophysiology, Causes, and Management Approaches. Zagazig Vet J. 2025;53(2):108-25.
  • 20. Imamura M, Scott NW, Wallace SA, Ogah JA, Ford AA, Dubos YA, vd. Interventions for treating people with symptoms of bladder pain syndrome: a network meta-analysis. Cochrane Database Syst Rev [İnternet]. 2020 [a.yer 21 Ağustos 2025];(7). Erişim adresi: https://www.cochranelibrary.com/cdsr/doi/10.1 002/14651858.CD013325.pub2/abstract
  • 21. Vasudevan V, Moldwin R. Addressing quality of life in the patient with interstitial cystitis/bladder pain syndrome. Asian J Urol. 2016;4(1):50.
  • 22. Ginkel C van, Martens F, Scholtes M, Heesakkers J, Janssen DA. Quality of life and treatment modalities in patients with interstitial cystitis: the patients’ perspective. İçinde: Healthcare [İnternet]. MDPI; 2024 [a.yer 21 Ağustos 2025]. s. 466. Erişim adresi: https://www.mdpi.com/2227-9032/12/4/466
  • 23. Jia X, Crouss T, Rana N, Whitmore KE. Complementary and Alternative Medicine for the Management of Interstitial Cystitis/Bladder Pain Syndrome: a Recent Update. Curr Bladder Dysfunct Rep. Eylül 2020;15(3):214-8.
There are 22 citations in total.

Details

Primary Language Turkish
Subjects Health Services and Systems (Other)
Journal Section Reviews
Authors

Aleyna Akdoğan 0009-0008-0954-8116

Ezgi Seyhan Ak 0000-0002-3679-539X

Publication Date November 10, 2025
Submission Date August 21, 2025
Acceptance Date October 7, 2025
Published in Issue Year 2025 Volume: 4 Issue: 2

Cite

APA Akdoğan, A., & Seyhan Ak, E. (2025). Kronik Mesane Ağrısı Yönetimi ve Yaşam Kalitesi. Balkan Sağlık Bilimleri Dergisi, 4(2), 67-77. https://doi.org/10.61830/balkansbd.1770090