Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler

Tuğba Buse Avcı; Zafer Ömer Özdemir

EN TR

Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler

Abstract

Mollusca (Yumuşakça) Arthrpoda’dan sonra en zengin tür sayısına sahip filumdur. Tür sayısındaki çeşitlilik, çok çeşitli morfolojileri ve ekolojik nişleri, kazanılmış immünolojik hafızaları bulunmadığı için çeşitli savunma mekanizmaları geliştirmeleri ve aydınlatılmamış çok sayıda aktif bileşiği bu grubu doğal ürün kimyası araştırmaları ve yeni ilaç keşfi için iyi bir aday haline getirmektedir. Deniz canlıları, özellikle yumuşakçalar, henüz keşfedilmemiş pek çok sekonder metabolit barındırdıkları için, büyük bir potansiyel barındırmaktadır.

Bu çalışmanın amacı, yumuşakça kimyası bilgimizdeki ana boşlukları tamamlamak için yumuşakça sekonder metabolitleri hakkındaki güncel literatürü incelemektir. Bu sayede, doğal ürün kimyası alanında gelecekte yapılacak araştırmalara katkı sağlanarak, hedeflerin iyileştirilmesine yardımcı olma imkânı doğacaktır.

Keywords

Mollusca,Antimikrobiyal peptitler,Doğal Ürün Kimyası,Sekonder metabolit

References

Avila, C. (2006). Molluscan natural products as biological models: chemical ecology, histology, and laboratory culture. Progress in Molecular and Subcellular Biology. https://doi.org/10.1007/978-3-540-30880-5_1
Bastos, P., Fracalossi, D. M., Chimal, M. E., Sánchez, A., & Rosas, C. (2020). Digestive enzymes and timing of digestion in Octopus vulgaris type II. Aquaculture Reports, 16, 100262. https://doi.org/10.1016/j.aqrep.2019.100262
Benkendorff, K. (2010). Molluscan biological and chemical diversity: Secondary metabolites and medicinal resources produced by marine molluscs. Biological Reviews, 85(4), 757–775. https://doi.org/10.1111/j.1469-185X.2010.00124.x
Carson, M. A., & Clarke, S. A. (2018). Bioactive compounds from marine organisms: Potential for bone growth and healing. Marine Drugs, 16(9). https://doi.org/10.3390/md16090340
Ciavatta, M. Letizia, Devi, P., Carbone, M., Mathieu, V., Kiss, R., Casapullo, A., & Gavagnin, M. (2016). Kahalalide F analogues from the mucous secretion of Indian sacoglossan mollusc Elysia ornata. Tetrahedron, 72(5), 625–631. https://doi.org/10.1016/J.TET.2015.12.003
Ciavatta, Maria Letizia, Lefranc, F., Carbone, M., Mollo, E., Gavagnin, M., Betancourt, T., … Kiss, R. (2017). Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance. Medicinal Research Reviews, 37(4), 702–801. https://doi.org/10.1002/med.21423
Costantino, V., Fattorusso, E., Mangoni, A., Perinu, C., Cirino, G., De Gruttola, L., & Roviezzo, F. (2009). Tedanol: A potent anti-inflammatory ent-pimarane diterpene from the Caribbean Sponge Tedania ignis. Bioorganic & Medicinal Chemistry, 17(21), 7542–7547. https://doi.org/10.1016/J.BMC.2009.09.010
El-Sorogy, A. S., Alharbi, T., Almadani, S., & Al-Hashim, M. (2019). Molluscan assemblage as pollution indicators in Al-Khobar coastal plain, Arabian Gulf, Saudi Arabia. Journal of African Earth Sciences, 158. https://doi.org/10.1016/j.jafrearsci.2019.103564
Esmaeelian, B., Benkendorff, K., Johnston, M. R., & Abbott, C. A. (2013). Purified brominated indole derivatives from dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines. Marine Drugs, 11(10), 3802–3822. https://doi.org/10.3390/md11103802
Etman, S. M., Elnaggar, Y. S. R., & Abdallah, O. Y. (2019). “Fucoidan, a natural biopolymer in cancer combating: From edible algae to nanocarrier tailoring.” International Journal of Biological Macromolecules, (xxxx). https://doi.org/10.1016/j.ijbiomac.2019.11.191

Ganesan, A. R., Saravana, M., Mohanram, G., Balasubramanian, B., Ho, I., Seedevi, P., … Ignacimuthu, S. (2019). Journal of King Saud University – Science Marine invertebrates ’ proteins : A recent update on functional property. Journal of King Saud University - Science, (xxxx). https://doi.org/10.1016/j.jksus.2019.12.003
Gupta, P., Arumugam, M., Azad, R. V., Saxena, R., Ghose, S., Biswas, N. R., & Velpandian, T. (2014). Screening of antiangiogenic potential of twenty two marine invertebrate extracts of phylum Mollusca from South East Coast of India. Asian Pacific Journal of Tropical Biomedicine, 4, S129–S138. https://doi.org/10.12980/APJTB.4.2014C701
Kanda, A., & Minakata, H. (2006). Isolation and characterization of a novel small cardioactive peptide-related peptide from the brain of Octopus vulgaris. Peptides, 27(7), 1755–1761. https://doi.org/10.1016/j.peptides.2005.12.006
Kaviarasan, T., Siva, S. R., & Yogamoorthi, A. (2012). RETRACTED: Antimicrobial secondary metabolites from marine gastropod egg capsules and egg masses. Asian Pacific Journal of Tropical Biomedicine, 2(11), 916–922. https://doi.org/10.1016/S2221-1691(12)60253-6
Kimbrough, K. L., Johnson, W. E., Lauenstein, G. G., Christensen, J. D., & Apeti, D. A. (2008). An Assessment of Two Decades of Contaminant Monitoring in the Nation’s Coastal Zone. Silver Spring, MD. NOAA Technical Memorandum NOS NCCOS 74 (Vol. 105).
Kocatepe, D., Turan, H., Üniversitesi, S., İşletmeciliği ve Otelcilik Yüksekokulu, T., İçecek İşletmeciliği Bölümü, Y., Ürünleri Fakültesi, S., … su ürünleri, K. (2012). Su Ürünleri Alerjisi Sea Food Allergy. Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 3(2), 46–51.
Kumar, A., & Jaitak, V. (2019, August 15). Natural products as multidrug resistance modulators in cancer. European Journal of Medicinal Chemistry. Elsevier Masson SAS. https://doi.org/10.1016/j.ejmech.2019.05.027
Kumar, P., Kannan, M., ArunPrasanna, V., Vaseeharan, B., & Vijayakumar, S. (2018). Proteomics analysis of crude squid ink isolated from Sepia esculenta for their antimicrobial, antibiofilm and cytotoxic properties. Microbial Pathogenesis, 116, 345–350. https://doi.org/10.1016/j.micpath.2018.01.039
Lopes, V. M., Rosa, R., & Costa, P. R. (2018). Presence and persistence of the amnesic shellfish poisoning toxin, domoic acid, in octopus and cuttlefish brains. Marine Environmental Research, 133(December 2017), 45–48. https://doi.org/10.1016/j.marenvres.2017.12.001
Lv, J., Zhao, J., Yang, D., Wu, H., & Cong, M. (2019). Tissue distribution and functional characterization of mytimacin-4 in Mytilus galloprovincialis. Journal of Invertebrate Pathology, 166. https://doi.org/10.1016/j.jip.2019.107215
Nie, S. Q., Li, T. L., Jiang, W. J., Xue, B. Y., Liang, A. H., Li, G. Q., & Yang, Q. (1994). [A comparative study on anti-ulcer action of unprepared and calcined oyster shell]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 19(7), 405—7, 446.
Öztürk, B., Doğan, A., Bitlis-Bakir, B., & Salman, A. (2014). Marine molluscs of the Turkish coasts: An updated checklist. Turkish Journal of Zoology, 38(6), 832–879. https://doi.org/10.3906/zoo-1405-78
Pati, P., Sahu, B. K., & Panigrahy, R. C. (2015). Marine molluscs as a potential drug cabinet: An overview. Indian Journal of Geo-Marine Sciences, 44(7), 961–970. Pereira, R. B., Andrade, P. B., & Valentão, P. (2016). Chemical diversity and biological properties of secondary metabolites from sea hares of Aplysia genus. Marine Drugs, 14(2). https://doi.org/10.3390/md14020039
Periyasamy, N., Arularasan, S., & Gayathri, S. (2012). Antibacterial activity of the tissue extracts of Conus betulinus and Conus inscriptus Linnaeus, 1758 (Mollusca: Gastropoda) from Nagapattinam, Southeast coast of India. Asian Pacific Journal of Tropical Disease, 2, S914–S919. https://doi.org/10.1016/S2222-1808(12)60291-6
Prokopov, I. A., Kovaleva, E. L., Minaeva, E. D., Pryakhina, E. A., Savin, E. V., Gamayunova, A. V., … Shikov, A. N. (2019, August 10). Animal-derived medicinal products in Russia: Current nomenclature and specific aspects of quality control. Journal of Ethnopharmacology. Elsevier Ireland Ltd. https://doi.org/10.1016/j.jep.2019.111933
Puyana, M., Pawlik, J., Blum, J., & Fenical, W. (2015). Metabolite variability in caribbean sponges of the genus aplysina. Brazilian Journal of Pharmacognosy, 25(6), 592–599. https://doi.org/10.1016/j.bjp.2015.08.002
Rudd, D., Ronci, M., Johnston, M. R., Guinan, T., Voelcker, N. H., & Benkendorff, K. (2015). Mass spectrometry imaging reveals new biological roles for choline esters and Tyrian purple precursors in muricid molluscs. Scientific Reports, 5(March), 1–13. https://doi.org/10.1038/srep13408
Russo, G. L., De Nisco, E., Fiore, G., Di Donato, P., D’Ischia, M., & Palumbo, A. (2003). Toxicity of melanin-free ink of Sepia officinalis to transformed cell lines: Identification of the active factor as tyrosinase. Biochemical and Biophysical Research Communications, 308(2), 293–299. https://doi.org/10.1016/S0006-291X(03)01379-2
Safavi-Hemami, H., Brogan, S. E., & Olivera, B. M. (2019). Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways. Journal of Proteomics, 190(January 2018), 12–20. https://doi.org/10.1016/j.jprot.2018.05.009
Sánchez, A. M., Malagarie-Cazenave, S., Olea, N., Vara, D., Cuevas, C., & Díaz-Laviada, I. (2008). Spisulosine (ES-285) induces prostate tumor PC-3 and LNCaP cell death by de novo synthesis of ceramide and PKCζ activation. European Journal of Pharmacology, 584(2–3), 237–245. https://doi.org/10.1016/J.EJPHAR.2008.02.011
Sousa, H., & Hinzmann, M. (2019). Review: Antibacterial components of the Bivalve’s immune system and the potential of freshwater bivalves as a source of new antibacterial compounds. Fish & Shellfish Immunology. https://doi.org/10.1016/j.fsi.2019.10.062
Valles-Regino, R., Mouatt, P., Rudd, D., Yee, L. H., & Benkendorff, K. (2016). Extraction and quantification of bioactive Tyrian purple precursors: A comparative and validation study from the hypobranchial gland of a muricid Dicathais orbita. Molecules, 21(12). https://doi.org/10.3390/molecules21121672
Wakimoto, T., Tan, K. C., & Abe, I. (2013). Ergot alkaloid from the sea slug Pleurobranchus forskalii. Toxicon, 72, 1–4. https://doi.org/10.1016/j.toxicon.2013.05.021
Wali, A. F., Majid, S., Rasool, S., Shehada, S. B., Abdulkareem, S. K., Firdous, A., … Rehman, M. U. (2019, September 1). Natural products against cancer: Review on phytochemicals from marine sources in preventing cancer. Saudi Pharmaceutical Journal. Elsevier B.V. https://doi.org/10.1016/j.jsps.2019.04.013
Wang, M., Wang, B., Liu, M., Jiang, K., & Wang, L. (2019). Comparative study of β-thymosin in two scallop species Argopecten irradians and Chlamys farreri. Fish and Shellfish Immunology, 86, 516–524. https://doi.org/10.1016/j.fsi.2018.11.050
Yokosaka, S., Izawa, A., Sakai, C., Sakurada, E., Morita, Y., & Nishio, Y. (2018). Synthesis and evaluation of novel dolastatin 10 derivatives for versatile conjugations. Bioorganic and Medicinal Chemistry, 26(8), 1643–1652. https://doi.org/10.1016/j.bmc.2018.02.011

Details

Primary Language

Turkish

Subjects

Pharmacology and Pharmaceutical Sciences

Journal Section

Review

Authors

Tuğba Buse Avcı ^*
0000-0002-0138-2480
Türkiye

Zafer Ömer Özdemir
0000-0002-8362-3136
Türkiye

Publication Date

December 31, 2019

Submission Date

December 27, 2019

Acceptance Date

December 30, 2019

Published in Issue

Year 2019 Volume: 1 Number: 1

IZ

https://izlik.org/JA68AA24XD

APA

Avcı, T. B., & Özdemir, Z. Ö. (2019). Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler. Journal of Integrative and Anatolian Medicine, 1(1), 42-54. https://izlik.org/JA68AA24XD

AMA

1.Avcı TB, Özdemir ZÖ. Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler. J. Integr. Anatol. Med. 2019;1(1):42-54. https://izlik.org/JA68AA24XD

Chicago

Avcı, Tuğba Buse, and Zafer Ömer Özdemir. 2019. “Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler”. Journal of Integrative and Anatolian Medicine 1 (1): 42-54. https://izlik.org/JA68AA24XD.

EndNote

Avcı TB, Özdemir ZÖ (December 1, 2019) Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler. Journal of Integrative and Anatolian Medicine 1 1 42–54.

IEEE

[1]T. B. Avcı and Z. Ö. Özdemir, “Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler”, J. Integr. Anatol. Med., vol. 1, no. 1, pp. 42–54, Dec. 2019, [Online]. Available: https://izlik.org/JA68AA24XD

ISNAD

Avcı, Tuğba Buse - Özdemir, Zafer Ömer. “Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler”. Journal of Integrative and Anatolian Medicine 1/1 (December 1, 2019): 42-54. https://izlik.org/JA68AA24XD.

JAMA

1.Avcı TB, Özdemir ZÖ. Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler. J. Integr. Anatol. Med. 2019;1:42–54.

MLA

Avcı, Tuğba Buse, and Zafer Ömer Özdemir. “Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler”. Journal of Integrative and Anatolian Medicine, vol. 1, no. 1, Dec. 2019, pp. 42-54, https://izlik.org/JA68AA24XD.

Vancouver

1.Tuğba Buse Avcı, Zafer Ömer Özdemir. Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler. J. Integr. Anatol. Med. [Internet]. 2019 Dec. 1;1(1):42-54. Available from: https://izlik.org/JA68AA24XD

J. Integr. Anatol. Med. (Abbreviated Title)

◆◆◆

e-ISSN: 2687-6345

◆◆◆

This work is licensed under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0).

Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler

Recent Developments in Natural Compounds Obtained from Marine Molluscs

Abstract

Keywords

Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

IZ

Cite

J. Integr. Anatol. Med. (Abbreviated Title)