APPLICATIONS OF HYPERICUM PERFORATUM IN THE TRADITIONAL MEDICINE FIELD

Year 2020, Volume: 1 Issue: 3, 10 - 22, 02.11.2020

Halil Mutlubaş , Zafer Ömer Özdemir

Abstract

Plants have been used in alternative medicine since ancient times. Usually people use plants for preventive purposes because they are of natural origin. However, the pharmacological and toxicological effects of plants are not sufficiently known. The hypericum perforatum, which is the best-known hypericum species belonging to the Hypericaceae family, is one of the most used medicinal plants in the world. Hypericum perforatum plant is especially preferred due to its antidepressant and wound healing properties. Many studies have been conducted on the biological activities and chemical composition of the Hypericum perforatum plant. According to the analysis, the active compounds of the hypericum perforatum species are hyperforin, which is the derivative of phloroglucinol, and hypericin, the compound of naphtodiantrone. The structure of hypericum perforatum also contains phenolic acids, tannins, flavonoids, xanthan compounds, and essential oils. In this study, the chemical compounds in the structure of the hypericum perforatum plant and the pharmacological effects of the hypericum perforatum plant are explained. Also in this study, vegetable oil and herbal tea were produced to examine the wound healing properties and antidepressant properties of the hypericum perforatum plant collected from Karaağaçlı plain of Manisa province. Vegetable oil and herbal tea produced are widely used in alternative medicine.

Keywords

Alternative medicine, biological activity, pharmacological action, hypericum perforatum

“HYPERICUM PERFORATUM”UN GELENEKSEL TIP ALANINDAKİ UYGULAMALARI

Abstract

Bitkiler, alternatif tıp alanında antik dönemlerden beri kullanılmaktadır. Genellikle insanlar bitkileri doğal kaynaklı olmasından dolayı koruyucu amaçlarda kullanırlar. Ancak, bitkilerin farmakolojik ve toksikolojik etkileri yeterince bilinmemektedir. Hypericaceae familyasına ait hypericum türlerinden en çok bilineni hypericum perforatum, dünyada en çok kullanılan tıbbi bitkilerdendir. Hypericum perforatum bitkisi özellikle antidepresan ve yara iyileştirici özelliklerinden dolayı tercih edilmektedir. Hypericum perforatum bitkisinin biyolojik aktiviteleri ve kimyasal bileşimi üzerine birçok çalışma yapılmıştır. Yapılan analizlere göre hypericum perforatum türünün aktif bileşikleri floroglusinol türevi olan hiperforin ve naftodiantron bileşiği olan hiperisindir. Hypericum perforatumun yapısında ayrıca fenolik asitler, tanenler, flavonoitler, ksanton bileşikleri ve uçucu yağlar bulunmaktadır. Bu çalışmada hypericum perforatum bitkisinin yapısında bulunan kimyasal bileşenler ile hypericum perforatum bitkisinin farmakolojik etkileri açıklanmıştır. Ayrıca bu çalışmada, Manisa ilinin Karaağaçlı ovasından toplanan hypericum perforatum bitkisinin yara iyileştirici özelliğini ve antidepresan özelliğini incelemek amacıyla bitkisel yağ ve bitkisel çay üretilmiştir. Üretilen bitkisel yağ ve bitkisel çay alternatif tıp alanında yaygın olarak kullanılmaktadır.

Keywords

Alternatif tıp, biyolojik aktivite, farmakolojik etki, hypericum perforatum

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