Evre I larinks kanseri tedavisinde 3 ve 5 Alan Yoğunluk Ayarlı Radyoterapi (3A-YART, 5A-YART) tekniklerinde karotis arterin dozimetrik olarak karşılaştırılması

Abstract

Bu çalışmada, radyoterapi (RT) uygulanmış Evre I larinks kanserli 18 hastanın arşiv materyali tedavi planlama sisteminden retrospektif olarak temin edilmiştir. Bu hastalara ait planlama amacıyla çekilmiş bilgisayarlı tomografi (BT) verileri kullanılarak MONACO 5.1 tedavi planlama sistemi ile hastaların 3 Alan Yoğunluk Ayarlı Radyoterapi (3A-YART) ve 5 Alan Yoğunluk Ayarlı Radyoterapi (5A-YART) tekniklerinin sanal tedavi planları oluşturulmuştur. Klinik Hedef Hacime (CTV) 63 Gy/fx toplam doz tanımlanmıştır. Tüm tedavi planları CTV’ yi kapsayacak şekilde tanımlanan dozun %95’ine normalize edilmiş ve inhomojenite düzeltmeleri yapılmıştır. Sanal planlar, sağ ve sol karotis arter için doz değerleri doz volüm histogramları (DVH) kullanılarak karşılaştırılmıştır. Elde edilen veriler Sosyal Bilimler için İstatistiksel Paket Programı (SPSS) kullanılarak analiz edilmiştir.

Keywords

• Larinks,karotis arter,YART,radyoterapi,doz

Dosimetric comparison of carotid artery with 3 and 5-Field Intensity Modulated Radiotherapy (3F-IMRT, 5F-IMRT) techniques in the treatment of stage I laryngeal cancer

Abstract

In this study, archival material of 18 patients with stage I laryngeal carcinoma treated with radiotherapy (RT) was retrospectively obtained from the treatment planning system. Using the (Computerized Tomography) scans, 3 Field Intensity Modulated Radiotherapy (3F-IMRT) and 5 Field Intensity Modulated Radiotherapy (5F-IMRT) virtual treatment plans were created for the patients with MONACO 5.1 treatment planning system. Prescripted dose for Clinical Target Volume (CTV) is 63 Gy/fx in total. All treatment plans were created to conform CTV and normalized to 95% of the prescripted dose. All inhomogeneity adjustments were made.  Virtual plans for dose values for right and left carotid arteries were compared by using Dose-Volume Histogram (DVH).  The obtained data were analyzed using Statistical Package for Social Sciences (SPSS).

Keywords

• Larynx,carotidartery,IMRT,radiotherapy,dose

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