Neonatal Dönem Buzağı İshallerinde Clostridium difficile

Abstract

Clostridium difficile, insanlarda antibiyotik ilişkili diyare vakalarının etiyolojik ajanı olmasının yanında çiftlik hayvanlarında özellikle neonatal dönemde ishallere sebep olmaktadır. Bakterinin birçok antimikrobiyal etken maddesine dirençli olması sebebiyle hastalık vakalarının tedavisi sınırlı kalabilmektedir. Etken toksin A, toksin B ve binary toksin olmak üzere üç toksin üretebilmekte ve klinik semptomlar bu toksinlerin bağırsaklarda meydana getirdiği hasar sonucunda ortaya çıkmaktadır. Bu derleme ile C. difficile’nin epidemiyolojisi, patogenezi, teşhisi, tedavisi ve buzağı ishallerinde rolü hakkında bilgi verilmektedir.

Keywords

• Clostridium difficile,neonatal buzağı,ishal

Clostridium difficile in Neonatal Calf Diarrhea

Abstract

Clostridium difficile is an etiological agent of antibiotic-associated diarrhea in humans, as well as diarrhea in farm animals, especially in the neonatal period. Because bacteria is resistant to many antimicrobial agents, the treatment of disease cases can be limited. The active toxin can produce three toxins, toxin A, toxin B and binary toxin, and clinical symptoms arise as a result of damage caused by these toxins in the intestines. This review provides information on the role of C. difficile in epidemiology, pathogenesis, diagnosis, treatment and calf diarrhea.

Keywords

• Clostridium difficile,neonatal calf,diarrhea

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