Chemical warfare agent recognition by using a practical mobile application for the first responders

Ruşen Koray Eyison; Özgün Aran; Onur Genç; Ali İhsan Uzar

doi:10.51539/biotech.1873814

Chemical warfare agent recognition by using a practical mobile application for the first responders

Abstract

This study describes the development of a mobile application designed to enable first responders and at-risk personnel to achieve rapid and accurate on-site identification of toxic chemical substances. The prompt identification of toxic agents-which can pose significant health risks through inhalation or dermal absorption-is critical for effective triage, appropriate medical intervention, and personnel safety. The mobile application integrates environmental cues with a comprehensive database of clinical signs and symptoms specific to chemical toxins. Its core functionality allows users to input observable environmental indicators, such as the odor, color, and nature of the smoke or vapor produced by chemical agents. Furthermore, it accounts for physical properties like density and volatility, such as whether the agent remains suspended in the air or settles on the ground. Simultaneously, the application guides first responders through a systematic assessment by processing environmental findings alongside the symptoms displayed by exposed individuals. By cross-referencing these environmental and clinical data points within an algorithm, the application provides a probable agent identification. By doing so, it enables first responders to rapidly implement appropriate decontamination and medical management protocols. Ultimately, this tool aims to protect first responders while improving clinical outcomes for casualties.

Keywords

Supporting Institution

The authors would like to express their gratitude to his respective academic institution, University of Health Sciences for providing the necessary environment and encouragement for the development of this study.

Ethical Statement

Ethics approval and consent to participate: not applicable. Consent for publication: not applicable.

Thanks

The authors thank Tolga Kaya at the University of Health Sciences, Institute of Defence Health Sciences for his support and academic environment during the preparation of this study.

References

Blain, P.G (2012) Biotoxins and bioterrorism: Ricin and saxitoxin. Toxicon: official journal of the International Society on Toxinology, 60:100.
Brown, J.L., Lyons, C.E., Toddes, C., Monko, T., and Tyshynsky, R (2021) Reevaluating tear gas toxicity and safety. Inhalation toxicology, 33:205–220.
Chauhan, S., Chauhan, S., D’Cruz, R., Faruqi, S., Singh, K.K., Varma, S., Singh, M., and Karthik, V (2008) Chemical warfare agents. Environmental toxicology and pharmacology, 26:113–122.
Cottin, A., Zulian, M., Pécuchet, N., Guilloux, A., and Katsahian, S (2024) MS-CPFI: A model-agnostic Counterfactual Perturbation Feature Importance algorithm for interpreting black-box Multi-State models. Artificial intelligence in medicine, 147:102741.
Dall, C (2012) The design, implementation, and evaluation of cells: A virtual smartphone architecture. ACM Transactions on Computer Systems (TOCS), 30:1–31.
Gabrielli, T.A.E., (2023) Incapacitating agents review: 20 years after Nord Ost Siege. Critical reviews in toxicology, 53:481–490.
González-Pérez, A (2022) Using mobile devices as scientific measurement instruments: Reliable android task scheduling. Pervasive and Mobile Computing, 81.
Gyllencreutz, L., 2024. Chemical incident preparedness among emergency medical service personnel. International Journal of Paramedicine, 5, 103–117.

Haines, D.D. and Fox, S.C., 2014. Acute and long-term impact of chemical weapons: Lessons from the Iran-Iraq War. Forensic science review, 26 (2), 97–114.
Harry, A.L. and Ternay, J.K., 2019. Brief history and use of chemical warfare agents in warfare and terrorism. CRC Press.
James, T., Collins, S., and Marczylo, T., 2021. Identification of novel simulants for toxic industrial chemicals and chemical warfare agents for human decontamination studies: A systematic review and categorisation of physicochemical characteristics. International journal of environmental research and public health, 18 (16), 8681.
Killiam, A. and Caycedo, A., 2024. Ciottone’s Disaster Medicine. Elsevier.
Kim, K., Tsay, O.G., Atwood, D.A., and Churchill, D.G., 2011. Destruction and detection of chemical warfare agents. Chemical reviews, 111 (9), 5345–5403.
Kuča, K. and Pohanka, M (2010) Chemical warfare agents. In: Experientia Supplementum. Basel: Birkhäuser Basel, 543–558.
Kumar, V., Kim, H., Pandey, B., James, T.D., Yoon, J., and Anslyn, E.V (2023) Recent advances in fluorescent and colorimetric chemosensors for the detection of chemical warfare agents: a legacy of the 21st century. Chemical Society reviews, 52:663–704.
Lee, E.C (2003) Clinical manifestations of sarin nerve gas exposure. JAMA: the journal of the American Medical Association, 290:659–662.
Melenevych, A., Martovytskyi, D., and Molotyagin, D (2022) Hazardous and toxic substances poisoning in wartime and peacetime. Classification of hazardous chemicals. Mechanism of toxic action. Clinical manifestations of poisoning with chemical agents.
Newgard, C.D., Schmicker, R.H., Hedges, J.R., Trickett, J.P., Davis, D.P., Bulger, E.M., Aufderheide, T.P., Minei, J.P., Hata, J.S., Gubler, K.D., Brown, T.B., Yelle, J.-D., Bardarson, B., Nichol, G., and Resuscitation Outcomes Consortium Investigators (2010) Emergency medical services intervals and survival in trauma: assessment of the “golden hour” in a North American prospective cohort. Annals of emergency medicine, 55:235-246.
Rice, H (2016) CHAPTER 3. Toxicology of organophosphorus nerve agents. In: Issues in Toxicology. Cambridge: Royal Society of Chemistry, 81:116.
Szinicz, L (2005) History of chemical and biological warfare agents. Toxicology, 214:167–181.
Tozlu, S., Senel, M., Mao, W., and Keshavarzian, A (2012) Wi-Fi enabled sensors for internet of things: A practical approach. IEEE communications magazine, 50:134–143.
Zulfiqar, N (2025) Chemical weapons in warfare: An in-depth analysis of classifications and profound effects on human physiology. In: Available at SSRN 5249712.

Details

Primary Language

English

Subjects

Biomedical Engineering (Other)

Journal Section

Research Article

Authors

Ruşen Koray Eyison ^*
0000-0003-0151-6546
Türkiye

Özgün Aran This is me
0000-0001-7738-0724
Türkiye

Onur Genç This is me
0000-0003-1261-4686
Türkiye

Ali İhsan Uzar This is me
0000-0003-0889-1496
Türkiye

Publication Date

June 29, 2026

Submission Date

January 28, 2026

Acceptance Date

May 4, 2026

Published in Issue

Year 2026 Volume: 7 Number: 1

DOI

https://doi.org/10.51539/biotech.1873814

IZ

https://izlik.org/JA33LF62SK

Cite

RIS / Bibtex

APA

Eyison, R. K., Aran, Ö., Genç, O., & Uzar, A. İ. (2026). Chemical warfare agent recognition by using a practical mobile application for the first responders. Bulletin of Biotechnology, 7(1), 28-38. https://doi.org/10.51539/biotech.1873814

AMA

1.Eyison RK, Aran Ö, Genç O, Uzar Aİ. Chemical warfare agent recognition by using a practical mobile application for the first responders. Bull. Biotechnol. 2026;7(1):28-38. doi:10.51539/biotech.1873814

Chicago

Eyison, Ruşen Koray, Özgün Aran, Onur Genç, and Ali İhsan Uzar. 2026. “Chemical Warfare Agent Recognition by Using a Practical Mobile Application for the First Responders”. Bulletin of Biotechnology 7 (1): 28-38. https://doi.org/10.51539/biotech.1873814.

EndNote

Eyison RK, Aran Ö, Genç O, Uzar Aİ (June 1, 2026) Chemical warfare agent recognition by using a practical mobile application for the first responders. Bulletin of Biotechnology 7 1 28–38.

IEEE

[1]R. K. Eyison, Ö. Aran, O. Genç, and A. İ. Uzar, “Chemical warfare agent recognition by using a practical mobile application for the first responders”, Bull. Biotechnol., vol. 7, no. 1, pp. 28–38, June 2026, doi: 10.51539/biotech.1873814.

ISNAD

Eyison, Ruşen Koray - Aran, Özgün - Genç, Onur - Uzar, Ali İhsan. “Chemical Warfare Agent Recognition by Using a Practical Mobile Application for the First Responders”. Bulletin of Biotechnology 7/1 (June 1, 2026): 28-38. https://doi.org/10.51539/biotech.1873814.

JAMA

1.Eyison RK, Aran Ö, Genç O, Uzar Aİ. Chemical warfare agent recognition by using a practical mobile application for the first responders. Bull. Biotechnol. 2026;7:28–38.

MLA

Eyison, Ruşen Koray, et al. “Chemical Warfare Agent Recognition by Using a Practical Mobile Application for the First Responders”. Bulletin of Biotechnology, vol. 7, no. 1, June 2026, pp. 28-38, doi:10.51539/biotech.1873814.

Vancouver

1.Ruşen Koray Eyison, Özgün Aran, Onur Genç, Ali İhsan Uzar. Chemical warfare agent recognition by using a practical mobile application for the first responders. Bull. Biotechnol. 2026 Jun. 1;7(1):28-3. doi:10.51539/biotech.1873814