Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium

Dilek Memiş; Müşerref Otkun; Meral Bahar; Necdet Süt

TR EN

Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium

Öz

Objectives: We studied in vivo growth of Escherichia coli in atracurium, rocuronium, mivacurium, cisatracurium, pancuronium, and vecuronium. Patients and Methods: The pathogen was exposed to atracurium, rocuronium, mivacurium, cisatracurium, pancuronium and vecuronium for 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, and 24 h at room temperature, respectively. Results: The mean colony counts of Escherichia coli after exposure to rocuronium was significantly lower than the counts after exposure to atracurium, mivacurium, cisatracurium, pancuronium and vecuronium (p=0.002, 0.000, 0.000, 0.001, and 0.002, respectively). No significant difference was found with respect to the mean colony counts with atracurium, mivacurium, cisatracurium, pancuronium and vecuronium (p&lt;0.05). Conclusion: Rocuronium had more powerful antimicrobial effects than the other neuromuscular agents. Turkish Başlık: Atrakuryum, Rokuronyum, Mivakuryum, Sisatrakuryum, Pankuronyum ve Vekuronyumda Escherichia Coli Üremesi Anahtar Kelimeler: Atrakuryum, mivakuryum, sisatrakuryum, pankuronyum, vekuronyum, bakterial kontaminasyon, Escherichia coli Amaç: Biz çalışmamızda atrakuryum, rokuronyum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumun Escherichia coli üremesi üzerine olan etkinliğini araştırdık. Hastalar ve Yöntemler: Patojen bakteri, atrakuryum, rokuronyum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyum ile 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, ve 24 saat oda sıcaklığında temas ettirildi. Bulgular: Escherichia coli ortalama koloni sayısı rokuronyumda istatiksel anlamlı olarak atrakuryum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumdan daha düşük saptandı (sırasıyla p=0.002, 0.000, 0.000, 0.001, ve 0.002). Atrakuryum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumda ortalama koloni sayısı açısından anlamlı fark saptanmadı (p&lt;0.05). Sonuç: Rokuronyum, diğer nöromusküler kas gevşetici ajanlardan daha kuvvetli antimikrobiyal etki gösterdi.

Anahtar Kelimeler

Atracurium, rocuronium, mivacurium, cisatracurium, pancuronium, vecuronium, bacterial contamination, Escherichia coli

Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium

Abstract

Objectives: We studied in vivo growth of Escherichia coli in atracurium, rocuronium, mivacurium, cisatracurium, pancuronium, and vecuronium. Patients and Methods: The pathogen was exposed to atracurium, rocuronium, mivacurium, cisatracurium, pancuronium and vecuronium for 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, and 24 h at room temperature, respectively. Results: The mean colony counts of Escherichia coli after exposure to rocuronium was significantly lower than the counts after exposure to atracurium, mivacurium, cisatracurium, pancuronium and vecuronium (p=0.002, 0.000, 0.000, 0.001, and 0.002, respectively). No significant difference was found with respect to the mean colony counts with atracurium, mivacurium, cisatracurium, pancuronium and vecuronium (p&lt;0.05). Conclusion: Rocuronium had more powerful antimicrobial effects than the other neuromuscular agents. Turkish Başlık: Atrakuryum, Rokuronyum, Mivakuryum, Sisatrakuryum, Pankuronyum ve Vekuronyumda Escherichia Coli Üremesi Anahtar Kelimeler: Atrakuryum, mivakuryum, sisatrakuryum, pankuronyum, vekuronyum, bakterial kontaminasyon, Escherichia coli Amaç: Biz çalışmamızda atrakuryum, rokuronyum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumun Escherichia coli üremesi üzerine olan etkinliğini araştırdık. Hastalar ve Yöntemler: Patojen bakteri, atrakuryum, rokuronyum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyum ile 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, ve 24 saat oda sıcaklığında temas ettirildi. Bulgular: Escherichia coli ortalama koloni sayısı rokuronyumda istatiksel anlamlı olarak atrakuryum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumdan daha düşük saptandı (sırasıyla p=0.002, 0.000, 0.000, 0.001, ve 0.002). Atrakuryum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumda ortalama koloni sayısı açısından anlamlı fark saptanmadı (p&lt;0.05). Sonuç: Rokuronyum, diğer nöromusküler kas gevşetici ajanlardan daha kuvvetli antimikrobiyal etki gösterdi.

Keywords

Atracurium, rocuronium, mivacurium, cisatracurium, pancuronium, vecuronium, bacterial contamination, Escherichia coli

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Dilek Memiş This is me

Müşerref Otkun This is me

Meral Bahar This is me

Necdet Süt This is me

Publication Date

February 1, 2009

Submission Date

August 6, 2014

Acceptance Date

-

Published in Issue

Year 2009 Volume: 2009 Number: 2

IZ

https://izlik.org/JA59FZ76HP

Cite

RIS / Bibtex

APA

Memiş, D., Otkun, M., Bahar, M., & Süt, N. (2009). Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium. Balkan Medical Journal, 2009(2). https://izlik.org/JA59FZ76HP

AMA

1.Memiş D, Otkun M, Bahar M, Süt N. Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium. Balkan Medical Journal. 2009;2009(2). https://izlik.org/JA59FZ76HP

Chicago

Memiş, Dilek, Müşerref Otkun, Meral Bahar, and Necdet Süt. 2009. “Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium”. Balkan Medical Journal 2009 (2). https://izlik.org/JA59FZ76HP.

EndNote

Memiş D, Otkun M, Bahar M, Süt N (February 1, 2009) Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium. Balkan Medical Journal 2009 2

IEEE

[1]D. Memiş, M. Otkun, M. Bahar, and N. Süt, “Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium”, Balkan Medical Journal, vol. 2009, no. 2, Feb. 2009, [Online]. Available: https://izlik.org/JA59FZ76HP

ISNAD

Memiş, Dilek - Otkun, Müşerref - Bahar, Meral - Süt, Necdet. “Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium”. Balkan Medical Journal 2009/2 (February 1, 2009). https://izlik.org/JA59FZ76HP.

JAMA

1.Memiş D, Otkun M, Bahar M, Süt N. Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium. Balkan Medical Journal. 2009;2009. Available at https://izlik.org/JA59FZ76HP.

MLA

Memiş, Dilek, et al. “Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium”. Balkan Medical Journal, vol. 2009, no. 2, Feb. 2009, https://izlik.org/JA59FZ76HP.

Vancouver

1.Dilek Memiş, Müşerref Otkun, Meral Bahar, Necdet Süt. Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium. Balkan Medical Journal [Internet]. 2009 Feb. 1;2009(2). Available from: https://izlik.org/JA59FZ76HP