Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia

Volume: 32 Number: 2 April 1, 2015
  • Sibel Kabukçu Hacıoğlu
  • Mehmet Hilmi Doğu
  • İsmail Sarı
  • Ali Keskin
EN

Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia

Abstract

Background: Glanzmann Thrombasthenia (GT) is a genetic platelet dysfunction and a life threatening disease. Ankaferd Blood Stopper (ABS) is a topical hemostatic agent of herbal origin which has been recently made available for clinical use. Its hemostatic effect is independent from blood clotting factors and occurs as a result of the aggregation of focal red blood cells by an encapsulated protein web. Case Report: In this paper, a patient with GT is presented in whom 3 months of gastrointestinal bleeding refractory to all medical therapies was controlled within a short time of using oral ABS. Conclusion: The difference between this patient and other cases presented in the medical literature is the oral use of ABS. Thus, this patient may contribute to the medical community in showing the safety and efficacy of systemic (oral) ABS in patients with disorders of coagulation. However, there is a need for more patient experiences.

Keywords

References

  1. 1. Franchini M, Favaloro EJ, Lippi G. Glanzmann thrombasthenia: an update. Clin Chim Acta 2010;41:1-6. [CrossRef]
  2. 2. Beyazit Y, Kurt M, Kekilli M, Goker H, Haznedaroglu IC. Evaluation of hemostatic effects of Ankaferd as an alternative medicine. Altern Med Rev 2010;15:329-36.
  3. 3. Beyazit Y, Kekilli M, Haznedaroglu IC, Kayacetin E, Basaranoglu M. Ankaferd hemostat in the management of gastrointestinal hemorrhages. World J Gastroenterol 2011;17:3962-70. [CrossRef]
  4. 4. Beyazit Y, Kart T, Kuscu A, Arslan A, Kurt M, Aktas B, et al. Successful management of bleeding after dental procedures with application of blood stopper: a single center prospective trial. J Contemp Dent Pract 2011;12:379-84. [CrossRef]
  5. 5. Bakdash S, Lyons JM, Bastacky SI, Pezzone MA, McGee JB, Schoen RE, et al. Management of persistent gastric bleeding in a patient with Glanzmann’s thrombasthenia. Am J Hematol 2008;83:411-5. [CrossRef]
  6. 6. Bhat S, Yadav SP, Anjan M, Dinand V, Sachdeva A. Recombinant activated factor VII usage in life threatening hemorrhage: a pediatric experience. Indian J Pediatr 2011;78:961-8. [CrossRef]
  7. 7. Kazancıoğlu HO, Cakır O, Ak G, Zülfikar B. The Effectiveness of a New Hemostatic Agent (Ankaferd Blood Stopper) for the Control of Bleeding following Tooth Extraction in Hemophilia: A Controlled Clinical Trial. Turk J Haematol 2013;30:19-24. [CrossRef]
  8. 8. Baykul T, Alanoglu EG, Kocer G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. J Contemp Dent Pract 2010;11:88-94.

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Sibel Kabukçu Hacıoğlu This is me

Mehmet Hilmi Doğu This is me

İsmail Sarı This is me

Ali Keskin This is me

Publication Date

April 1, 2015

Submission Date

April 1, 2015

Acceptance Date

-

Published in Issue

Year 2015 Volume: 32 Number: 2

APA
Hacıoğlu, S. K., Doğu, M. H., Sarı, İ., & Keskin, A. (2015). Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia. Balkan Medical Journal, 32(2), 218-220. https://izlik.org/JA36HB84PX
AMA
1.Hacıoğlu S K, Doğu M H, Sarı İ, Keskin A. Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia. Balkan Medical Journal. 2015;32(2):218-220. https://izlik.org/JA36HB84PX
Chicago
Hacıoğlu, Sibel Kabukçu, Mehmet Hilmi Doğu, İsmail Sarı, and Ali Keskin. 2015. “Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient With Glanzmann Thrombasthenia”. Balkan Medical Journal 32 (2): 218-20. https://izlik.org/JA36HB84PX.
EndNote
Hacıoğlu S K, Doğu M H, Sarı İ, Keskin A (April 1, 2015) Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia. Balkan Medical Journal 32 2 218–220.
IEEE
[1]S. K. Hacıoğlu, M. H. Doğu, İ. Sarı, and A. Keskin, “Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia”, Balkan Medical Journal, vol. 32, no. 2, pp. 218–220, Apr. 2015, [Online]. Available: https://izlik.org/JA36HB84PX
ISNAD
Hacıoğlu, Sibel Kabukçu - Doğu, Mehmet Hilmi - Sarı, İsmail - Keskin, Ali. “Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient With Glanzmann Thrombasthenia”. Balkan Medical Journal 32/2 (April 1, 2015): 218-220. https://izlik.org/JA36HB84PX.
JAMA
1.Hacıoğlu S K, Doğu M H, Sarı İ, Keskin A. Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia. Balkan Medical Journal. 2015;32:218–220.
MLA
Hacıoğlu, Sibel Kabukçu, et al. “Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient With Glanzmann Thrombasthenia”. Balkan Medical Journal, vol. 32, no. 2, Apr. 2015, pp. 218-20, https://izlik.org/JA36HB84PX.
Vancouver
1.Sibel Kabukçu Hacıoğlu, Mehmet Hilmi Doğu, İsmail Sarı, Ali Keskin. Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia. Balkan Medical Journal [Internet]. 2015 Apr. 1;32(2):218-20. Available from: https://izlik.org/JA36HB84PX