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Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey

Year 2011, , 37 - 42, 01.01.2011
https://doi.org/10.5174/tutfd.2009.02681.2

Abstract

Objective: In spite of the wide prevalence and growing incidence of herpes simplex virus type 1 infection (HSV-1), relatively few data have been published regarding the seroepidemiology of the infection in the Turkish population. The study was designed to determine the age and sex-specific seroepidemiology of HSV-1 infection in the Black Sea region of Turkey. Material and Methods: Between March 1 and April 30, 2007, 1072 blood samples were randomly collected and examined by virus neutralization test (VNT) from patients aged 5-84 years who were referred to the University hospital outpatient clinics for various reasons in Black Sea Region of Turkey. Results: Overall HSV-1 seroprevalence was 59.7% (640/1072), and 58% of males (283/490) and 62% of females (357/582) were HSV-1 positive (p>0.05). In the group aged 15-19, seropositivity was significantly higher than in the group aged 19-24 (p=0.0333). Conclusion: Subgroup analysis indicates a higher HSV-1 infection seropositivity than had been estimated in children and adolescents in the Black Sea region of Turkey. The high prevalence of HSV-1 infection in children underlines the need for education among potential risk groups.

References

  • Brugha R, Keersmaekers K, Renton A, Meheus A. Genital herpes infection: a review. Int J Epidemiol. 1997;26:698-709.
  • Nahmias AJ, Lee FK, Beckman-Nahmias S. Sero-epidemiological and sociological patterns of herpes simplex virus infection in the world. Scand J Infect Dis 1990;69:19-36.
  • Corey L, Spear PG. Infections with herpes simplex viruses. N Engl J Med. 1986;314:749-57.
  • Mbopi-Kéou FX, Grésenguet G, Mayaud P, Weiss HA, Go- pal R, Matta M et al. Interactions between herpes simplex vi- rus type 2 and human immunodeficiency virus type 1 infection in African women: opportunities for intervention. J Infect Dis. 2000;182:1090-6.
  • Auvert B, Ballard R, Campbell C, Caraël M, Carton M, Fehler G et al. HIV infection among youth in a South African mining town is associated with herpes simplex virus-2 seropositivity and sexual behaviour. AIDS 2001;15:885-98.
  • Gwanzura L, McFarland W, Alexander D, Burke RL, Katzenstein D. Association between human immunodeficiency virus and her- pes simplex virus type 2 seropositivity among male factory work- ers in Zimbabwe. J Infect Dis 1998;177:481-4.
  • Wald A, Link K. Risk of human immunodeficiency virus infection in herpes simplex virus type 2–seropositive persons: a meta-anal- ysis. J Infect Dis 2002;185:45-52.
  • Smith JS, Robinson NJ. Age-specific prevalence of infection with herpes simplex virus types 2 and 1: a global review. J Infect Dis 2002;186:3-28.
  • Artiran Igde F, Igde M, Yazici Z, Okur Gumusova S, Birinci A, Sancak R et al. Distribution of HSV-1 IgG antibodies by two methods comparing in Turkish atopic children. New Microbiol 2007;30:109-12.
  • Askun D, Ataca B. Sexuality related attitudes and behaviors of Turkish university students. Arch Sex Behav 2007;36:741-52.
  • Lennette, EH. General principles underlying laboratory diag- nosis of viral and rickettsial infections. In.E.H.Lennette and J.N.Schmidtt (eds). Diagnostic procedures for virus and ricketsial disease. New York, Am.Public Health Association, 3rd edition, 1964;3:48-50.
  • Frey HR, Liess B. Vermehrungskinetik und verwendbarkeit einer stark cythopathogen VD-MD virusstammes für diagnostische un- tersuchugen mit der Mikrotiter Method. Zentralbl Veterinarmed B 1971;18:61-71.
  • Dolar N, Serdaroglu S, Yilmaz G, Ergin S. Seroprevalence of her- pes simplex virus type 1 and type 2 in Turkey. J Eur Acad Derma- tol Venereol 2006;20:1232-6.
  • Pebody RG, Andrews N, Brown D, Gopal R, De Melker H, Fran- çois G et al. The seroepidemiology of herpes simplex virus type 1 and 2 in Europe. Sex Transm Infect 2004;80:185-91.
  • Papadogeorgakis H, Caroni C, Katsambas A, Pimenta JM, Avde- liodi C, Kotrotsou T et al. Herpes simplex virus seroprevalence among children, adolescents and adults in Greece. Int J STD AIDS 2008;19:272-8.
  • Ibrahim AI, Kouwatli KM, Obeid MT. Frequency of herpes sim- plex virus in Syria based on type-specific serological assay. Saudi Med J 2000;21:355–60.
  • Ghebreidan H, Ruden U, Cox S, Wahren B, Grandien M. Prevelance of herpes simplex virus types 1 and 2, cytomegalo- virus and varicella-zoster virus infection in Eriteria. J. Clin. Virol 1999:12;53-64.
  • Becker TM, Magder L, Harrison HR. The epidemiology of infec- tion with the human herpesviruses in Navajo children. Am. J. Epi- demiol 1988;127:1071-8.
  • Ibrahim AI, Kouwatli KM, Obeid MT. Frequency of herpes sim- plex virus in Syria based on type-specific serological assay. Saudi Med J 2000;21:355–60.
  • Wutzler P, Doerr HW, Färber I, Eichhorn U, Helbig B, Sauerbrei A et al. Seroprevalence of herpes simplex virus type 1 and 2 in se- lected German populations-relevance for the incidence of genital herpes. J. Med. Virol 2000;61:201-7.
  • Isacsohn M, Smetana Z, Rones ZZ, Raveh D, Diamant Y, Samu- eloff A et al. A sero-epidemiological study of herpes virus type 1 and 2 infection in Israel. J Clin Virol 2002;24:85-92.
  • Vyse AJ, Gay NJ, Slomka MJ, Gopal R, Gibbs T, Morgan-Capner P et al. The burden of infection with HSV-1 and HSV-2 in England and Wales: implications for the changing epidemiology of genital herpes. Sex Transm Infect 2000;76:183-7.
  • Tunback P, Bergstrom T, Andersson AS., Nordin P, Krantz I, Low- hagen GB. Prevalence of herpes simplex virus antibodies in child- hood and adolescence: a cross sectional study. Scand. J. Infect. Dis 2003;35:498-502.
  • Davidovici BB, Gren M, Marouni MJ, Bassal R, Pimenta JM, Co- hen D. Seroprevalence of herpes simplex virus type 1 and 2 and correlates of infection in Israel. J. Infect 2006;52:367-73.
  • Langenberg AG, Corey L, Ashley RL, Leong WP, Straus SE. A pro- spective study of new infections with herpes simplex virus type 1 and type 2: Chiron HSV Vaccine Study Group. N Engl J Med 1999;341:1432-8.
  • Ross J, Smith I, Elton R. The epidemiology of herpes simplex types 1 and 2 infection of the genital tract in Edinburgh 1978-91. Genitourin Med 1993;69:381-3.
  • Gibson JJ, Hornung CA, Alexander GR, Lee FK, Potts WA, Nah- mias AJ. A cross-sectional study of herpes simplex virus type 1 and 2 in college students: occurrence and determinants of infec- tion. J Infect Dis 1990;162:306-12.
  • Peutherer JF, Smith IW, Robertson DH. Genital infection with her- pes simplex virus type 1. J Infect 1982;2:33-5.
  • Lavery HA, Connolly JH, Russell JD. Incidence of genital herpes in Northern Ireland in 1973–83 and herpes simplex types 1 and 2 isolated in 1982–84. Genitourin Med 1986;62:24-7.
  • Barton IG, Kinghorn GR, Najem S, Al-Omar LS, Potter CW. Inci- dence of herpes simplex virus types 1 and 2 isolated in patients with herpes genitalis in Sheffield. Br J Vener Dis 1982;58:44-7.

Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey

Year 2011, , 37 - 42, 01.01.2011
https://doi.org/10.5174/tutfd.2009.02681.2

Abstract

References

  • Brugha R, Keersmaekers K, Renton A, Meheus A. Genital herpes infection: a review. Int J Epidemiol. 1997;26:698-709.
  • Nahmias AJ, Lee FK, Beckman-Nahmias S. Sero-epidemiological and sociological patterns of herpes simplex virus infection in the world. Scand J Infect Dis 1990;69:19-36.
  • Corey L, Spear PG. Infections with herpes simplex viruses. N Engl J Med. 1986;314:749-57.
  • Mbopi-Kéou FX, Grésenguet G, Mayaud P, Weiss HA, Go- pal R, Matta M et al. Interactions between herpes simplex vi- rus type 2 and human immunodeficiency virus type 1 infection in African women: opportunities for intervention. J Infect Dis. 2000;182:1090-6.
  • Auvert B, Ballard R, Campbell C, Caraël M, Carton M, Fehler G et al. HIV infection among youth in a South African mining town is associated with herpes simplex virus-2 seropositivity and sexual behaviour. AIDS 2001;15:885-98.
  • Gwanzura L, McFarland W, Alexander D, Burke RL, Katzenstein D. Association between human immunodeficiency virus and her- pes simplex virus type 2 seropositivity among male factory work- ers in Zimbabwe. J Infect Dis 1998;177:481-4.
  • Wald A, Link K. Risk of human immunodeficiency virus infection in herpes simplex virus type 2–seropositive persons: a meta-anal- ysis. J Infect Dis 2002;185:45-52.
  • Smith JS, Robinson NJ. Age-specific prevalence of infection with herpes simplex virus types 2 and 1: a global review. J Infect Dis 2002;186:3-28.
  • Artiran Igde F, Igde M, Yazici Z, Okur Gumusova S, Birinci A, Sancak R et al. Distribution of HSV-1 IgG antibodies by two methods comparing in Turkish atopic children. New Microbiol 2007;30:109-12.
  • Askun D, Ataca B. Sexuality related attitudes and behaviors of Turkish university students. Arch Sex Behav 2007;36:741-52.
  • Lennette, EH. General principles underlying laboratory diag- nosis of viral and rickettsial infections. In.E.H.Lennette and J.N.Schmidtt (eds). Diagnostic procedures for virus and ricketsial disease. New York, Am.Public Health Association, 3rd edition, 1964;3:48-50.
  • Frey HR, Liess B. Vermehrungskinetik und verwendbarkeit einer stark cythopathogen VD-MD virusstammes für diagnostische un- tersuchugen mit der Mikrotiter Method. Zentralbl Veterinarmed B 1971;18:61-71.
  • Dolar N, Serdaroglu S, Yilmaz G, Ergin S. Seroprevalence of her- pes simplex virus type 1 and type 2 in Turkey. J Eur Acad Derma- tol Venereol 2006;20:1232-6.
  • Pebody RG, Andrews N, Brown D, Gopal R, De Melker H, Fran- çois G et al. The seroepidemiology of herpes simplex virus type 1 and 2 in Europe. Sex Transm Infect 2004;80:185-91.
  • Papadogeorgakis H, Caroni C, Katsambas A, Pimenta JM, Avde- liodi C, Kotrotsou T et al. Herpes simplex virus seroprevalence among children, adolescents and adults in Greece. Int J STD AIDS 2008;19:272-8.
  • Ibrahim AI, Kouwatli KM, Obeid MT. Frequency of herpes sim- plex virus in Syria based on type-specific serological assay. Saudi Med J 2000;21:355–60.
  • Ghebreidan H, Ruden U, Cox S, Wahren B, Grandien M. Prevelance of herpes simplex virus types 1 and 2, cytomegalo- virus and varicella-zoster virus infection in Eriteria. J. Clin. Virol 1999:12;53-64.
  • Becker TM, Magder L, Harrison HR. The epidemiology of infec- tion with the human herpesviruses in Navajo children. Am. J. Epi- demiol 1988;127:1071-8.
  • Ibrahim AI, Kouwatli KM, Obeid MT. Frequency of herpes sim- plex virus in Syria based on type-specific serological assay. Saudi Med J 2000;21:355–60.
  • Wutzler P, Doerr HW, Färber I, Eichhorn U, Helbig B, Sauerbrei A et al. Seroprevalence of herpes simplex virus type 1 and 2 in se- lected German populations-relevance for the incidence of genital herpes. J. Med. Virol 2000;61:201-7.
  • Isacsohn M, Smetana Z, Rones ZZ, Raveh D, Diamant Y, Samu- eloff A et al. A sero-epidemiological study of herpes virus type 1 and 2 infection in Israel. J Clin Virol 2002;24:85-92.
  • Vyse AJ, Gay NJ, Slomka MJ, Gopal R, Gibbs T, Morgan-Capner P et al. The burden of infection with HSV-1 and HSV-2 in England and Wales: implications for the changing epidemiology of genital herpes. Sex Transm Infect 2000;76:183-7.
  • Tunback P, Bergstrom T, Andersson AS., Nordin P, Krantz I, Low- hagen GB. Prevalence of herpes simplex virus antibodies in child- hood and adolescence: a cross sectional study. Scand. J. Infect. Dis 2003;35:498-502.
  • Davidovici BB, Gren M, Marouni MJ, Bassal R, Pimenta JM, Co- hen D. Seroprevalence of herpes simplex virus type 1 and 2 and correlates of infection in Israel. J. Infect 2006;52:367-73.
  • Langenberg AG, Corey L, Ashley RL, Leong WP, Straus SE. A pro- spective study of new infections with herpes simplex virus type 1 and type 2: Chiron HSV Vaccine Study Group. N Engl J Med 1999;341:1432-8.
  • Ross J, Smith I, Elton R. The epidemiology of herpes simplex types 1 and 2 infection of the genital tract in Edinburgh 1978-91. Genitourin Med 1993;69:381-3.
  • Gibson JJ, Hornung CA, Alexander GR, Lee FK, Potts WA, Nah- mias AJ. A cross-sectional study of herpes simplex virus type 1 and 2 in college students: occurrence and determinants of infec- tion. J Infect Dis 1990;162:306-12.
  • Peutherer JF, Smith IW, Robertson DH. Genital infection with her- pes simplex virus type 1. J Infect 1982;2:33-5.
  • Lavery HA, Connolly JH, Russell JD. Incidence of genital herpes in Northern Ireland in 1973–83 and herpes simplex types 1 and 2 isolated in 1982–84. Genitourin Med 1986;62:24-7.
  • Barton IG, Kinghorn GR, Najem S, Al-Omar LS, Potter CW. Inci- dence of herpes simplex virus types 1 and 2 isolated in patients with herpes genitalis in Sheffield. Br J Vener Dis 1982;58:44-7.
There are 30 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Füsun Artıran İğde This is me

Zafer Yazıcı This is me

Mahir İğde This is me

Publication Date January 1, 2011
Published in Issue Year 2011

Cite

APA İğde, F. A., Yazıcı, Z., & İğde, M. (2011). Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey. Balkan Medical Journal, 2011(1), 37-42. https://doi.org/10.5174/tutfd.2009.02681.2
AMA İğde FA, Yazıcı Z, İğde M. Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey. Balkan Medical Journal. January 2011;2011(1):37-42. doi:10.5174/tutfd.2009.02681.2
Chicago İğde, Füsun Artıran, Zafer Yazıcı, and Mahir İğde. “Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey”. Balkan Medical Journal 2011, no. 1 (January 2011): 37-42. https://doi.org/10.5174/tutfd.2009.02681.2.
EndNote İğde FA, Yazıcı Z, İğde M (January 1, 2011) Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey. Balkan Medical Journal 2011 1 37–42.
IEEE F. A. İğde, Z. Yazıcı, and M. İğde, “Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey”, Balkan Medical Journal, vol. 2011, no. 1, pp. 37–42, 2011, doi: 10.5174/tutfd.2009.02681.2.
ISNAD İğde, Füsun Artıran et al. “Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey”. Balkan Medical Journal 2011/1 (January 2011), 37-42. https://doi.org/10.5174/tutfd.2009.02681.2.
JAMA İğde FA, Yazıcı Z, İğde M. Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey. Balkan Medical Journal. 2011;2011:37–42.
MLA İğde, Füsun Artıran et al. “Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey”. Balkan Medical Journal, vol. 2011, no. 1, 2011, pp. 37-42, doi:10.5174/tutfd.2009.02681.2.
Vancouver İğde FA, Yazıcı Z, İğde M. Seroepidemiological Study of Herpes Simplex Virus Type 1 in the Black Sea Region of Turkey. Balkan Medical Journal. 2011;2011(1):37-42.