Effect of Young Maternal Age on Obstetric and Perinatal Outcomes: Results from the Tertiary Center in Turkey

Abstract

Background: Young maternal age is variously defined in studies of its effect on obstetrics and perinatal outcomes. Also, pregnancy has been reported as the leading cause of death in adolescent girls in low- and middle-income countries. Aims: The aim of the study was to evaluate whether young maternal age was associated with an increased risk of obstetrics and perinatal adverse outcomes. Study Design: Case-control study. Methods: This case-control study was derived from a database of the medical records between January 2008 and December 2012. In the present study, 1374 teenage pregnancy and 1294 adult pregnancy cases were included. After restriction of analyses to singleton primiparous women, 1282 teenage pregnancy and 735 adult pregnancy cases were analyzed. Maternal age was separated into three groups: 15 and less, 16-19, and 20-34 years. Adjusted odds ratios (ORs) were derived through logistic regression models for the potential confounding factors. Results: Adolescents aged 15 years and younger had higher risks of preterm delivery, early preterm delivery, intrauterine fetal death and neonatal death compared with women aged 20 to 34 years after adjustment for confounding factors. In addition, both groups of adolescents had higher risks for anemia and episiotomy and lower risk of cesarean delivery. The rates of preeclampsia, gestational diabetes, chronic diseases, intrauterine growth restriction (IUGR) were higher in the adult group. Conclusion: Younger maternal age was correlated with increased risks of preterm delivery, fetal and neonatal death and anemia.

Keywords

• Adolescent pregnancy, perinatal mortality, preterm delivery

References

1. 1. World Health Organization. Making Pregnancy Safer: Adolescent Pregnancy. 2011.
2. 2. de Vienne CM, Creveuil C, Dreyfus M. Does young maternal age increase the risk of adverse obstetric, fetal and neonatal outcomes: a cohort study. Eur J Obstet Gynecol Reprod Biol 2009;147:151-6. [CrossRef]
3. 3. Pergialiotis V, Vlachos DG, Gkioka E, Tsotra K, Papantoniou N, Vlachos GD. Teenage pregnancy antenatal and perinatal morbidity: Results from a tertiary centre in Greece. J Obstet Gynaecol 2014;19:1-5.
4. 4. Conde-Agudelo A, Belizán JM, Lammers C. Maternal-perinatal morbidity and mortality associated with adolescent pregnancy in Latin America: Cross-sectional study. Am J Obstet Gynecol 2005;192:342-9. [CrossRef]
5. 5. Ganchimeg T, Mori R, Ota E, Koyanagi A, Gilmour S, Shibuya K, et al. Maternal and perinatal outcomes among nulliparous adolescents in low- and middle-income countries: a multi-country study. BJOG 2013;120:1622-30. [CrossRef]
6. 6. Ganchimeg T, Ota E, Morisaki N, Laopaiboon M, Lumbiganon P, Zhang J, et al; WHO Multicountry Survey on Maternal Newborn Health Research Network. WHO Multicountry Survey on Maternal Newborn Health Research Network. Pregnancy and childbirth outcomes among adolescent mothers: a World Health Organization multicountry study. BJOG 2014;121:40-8. [CrossRef]
7. 7. Thaithae S, Thato R. Obstetric and perinatal outcomes of teenage pregnancies in Thailand. J Pediatr Adolesc Gynecol 2011;24:342-6. [CrossRef]
8. 8. Shrim A, Ates S, Mallozzi A, Brown R, Ponette V, Levin I, et al. Is young maternal age really a risk factor for adverse pregnancy outcome in a canadian tertiary referral hospital? J Pediatr Adolesc Gynecol 2011;24:218-22. [CrossRef]

9. 9. Gibbs CM, Wendt A, Peters S, Hogue CJ. The impact of early age at first childbirth on maternal and infant health. Paediatr Perinat Epidemiol 2012;26:259-84. [CrossRef]
10. 10. Bildircin FD, Kurtoglu E, Kokcu A, Işik Y, Ozkarci M, Kuruoglu S. Comparison of perinatal outcome between adolescent and adult pregnancies. J Matern Fetal Neonatal Med 2014;27:829-32. [CrossRef]