Hemophagocytosis in the Acute Phase of Fatal Kawasaki Disease in a 4 Month-Old Girl

Year 2016, Volume: 33 Issue: 4, 470 - 472, 01.07.2016

Vehbi Doğan Erhan Karaaslan Samet Özer Rüveyda Gümüşer Resul Yılmaz

Abstract

Background: Kawasaki disease is a systemic vasculitis
predominately affecting coronary arteries. Hemophagocytic
lymphohistiocytosis can complicate the
course of Kawasaki disease. Rare cases of secondary
hemophagocytic lymphohistiocytosis occurring during
the acute phase of Kawasaki disease have been
reported.
Case Report: We report here a 4 month-old girl with
diffuse coronary ectasia and secondary hemophagocytic
lymphohistiocytosis occurring during the acute
phase of incomplete Kawasaki disease.
Conclusion: Due to the large overlap in clinical symptoms,
the presence of atypical findings for Kawasaki
disease should suggest the possible diagnosis of hemophagocytic
lymphohistiocytosis in these patients

Keywords

Coronary artery dilatation , hemophagocytic lymphohistiocytosis , Kawasaki disease , macrophage activation syndrome

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