Hyoid Bone and Thyroid Cartilage Metastases from Sigmoid Colon Adenocarcinoma: A Case Report

Abstract

Background: Secondary tumours of the hyoid bone and thyroid cartilage are extremely rare. In this paper, we present a case of the hyoid bone and thyroid cartilage metastases in a patient treated for sigmoid colon adenocarcinoma. Case Report: Four years after sigmoid colon adenocarcinoma was diagnosed and treated with surgery and chemotherapy, the patient developed bone metastases in the left sacroiliac joint and right proximal humerus. Although the patient did not complain of any related symptoms, in a bone scintigraphy the accumulation of Technetium-99m was incidentally detected in the two sites of the anterior neck. On ultrasound examination there were two hyperechoic and heterogeneous masses with calcifications placed in front of the hyoid bone and thyroid cartilage. Computerized tomography demonstrated massive hyoid bone and thyroid cartilage destruction. Conclusion: In patients with progressive sigmoid colon adenocarcinoma, destruction of the hyoid bone and thyroid cartilage could be suspected for metastases

Keywords

• Hyoid bone, thyroid cartilage, adenocarcinoma metastases, computerized tomography, bone scintigraphy

References

1. 1. Timon CI, Gullane PJ, Brown D, Van Nostrand AW. Hyoid bone involvement by squamous cell carcinoma: clinical and pathological features. Laryngoscope 1992;102:515-20.
2. 2. Iguchi H, Okabe Y, Takayama M, Wada T, Hachiya K, Matsushita N, et al. Solitary hyoid bone metastasis from hepatocellular carcinoma treated with surgery. Nihon Jibiinkoka Gakkai Kaiho 2012;115:783-6.
3. 3. Lee HS, Lee JH, Kim SW, Lee KD. Metastatic renal cell carcinoma to the hyoid bone. Otolaryngol Head Neck Surg 2010;142:913-4.
4. 4. Ozcan Kara P, Kara Gedik G, Sarı O, Ozbek O. Rare Thyroid Cartilage and Diaphragm Metastases from Lung Cancer Visualized on F-18 FDG-PET/ CT Imaging. Mol Imaging Radionucl Ther 2011;20:70-2.
5. 5. Rampa M, Battaglia L, Caprotti A, Gazzano G, Prestianni P, Muscarà C, et al. Metastasis of sigmoid colon cancer in cryptorchid testis: report of a case. Tumori 2012;98:63-6.
6. 6. Marioni G, De Filippis C, Ottaviano G, Lorusso M, Staffieri C, Bernini G, et al. Laryngeal metastasis from sigmoid colon adenocarcinoma followed by peristomal recurrence. Acta Otolaryngol 2006;126:661-3.
7. 7. Onesti JK, Mascarenhas CR, Chung MH, Davis AT. Isolated metastasis of colon cancer to the scapula: is surgical resection warranted? World J Surg Oncol 2011;9:137.
8. 8. Amri R, Bordeianou LG, Sylla P, Berger D. Variations in Metastasis Site by Primary Location in Colon Cancer. J Gastrointest Surg 2015;19:1522-7.

9. 9. Rui Y, Wang C, Zhou Z, Zhong X, Yu Y. K-Ras mutation and prognosis of colorectal cancer: a meta-analysis. Hepatogastroenterology 2015;62:19- 24.
10. 10. Batsakis JG, Luna MA, Byers RM. Metastases to the larynx. Head Neck Surg 1985;7:458-60.