Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey

Ahmet Arvas; Haluk Çokuğraş; Emel Gür; Nevriye Gönüllü; Zeynep Taner; Hrisi Bahar Tokman

Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey

Abstract

Aims: To determine the prevalence of nasopharyngeal carriage of Streptococcus pneumoniae in healthy children aged 0-6 years who were vaccinated with pneumococcal conjugate vaccine. Methods: This cross-sectional study was conducted on 150 healthy Turkish children between 1 month and 6 years of age. Serotyping was performed and risk factors of carriage were evaluated. Results: The overall carriage rate was 14%. Vaccine type serotypes were determined in 17 (12.6%) children who received full-dose PCV13 vaccine. The highest carriage rate was observed among children younger than 24 months (76.2%). In multivariate analysis, respiratory infection in recent months, age, attendance at a day-care center and antibiotic usage were not statistically significant risk factors for carriage. Overall, S. pneumoniae strains were considered as penicillin susceptible and antimicrobial resistance was limited. Conclusion: We observed a low rate of pneumococcal carriage in children after PCV13 implementation compared with that of children receiving PCV7. Although it was reduced, vaccine serotype colonization in PCV13-vaccinated children remains persistent.

Keywords

Children, nasopharyngeal carriage, pneumococcal conjugate vaccine, Streptococcus pneumoniae

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Ahmet Arvas This is me

Haluk Çokuğraş This is me

Emel Gür This is me

Nevriye Gönüllü This is me

Zeynep Taner This is me

Hrisi Bahar Tokman This is me

Publication Date

July 1, 2017

Submission Date

July 1, 2017

Acceptance Date

-

Published in Issue

Year 2017 Volume: 34 Number: 4

IZ

https://izlik.org/JA22WK35DD

Cite

RIS / Bibtex

APA

Arvas, A., Çokuğraş, H., Gür, E., Gönüllü, N., Taner, Z., & Tokman, H. B. (2017). Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey. Balkan Medical Journal, 34(4). https://izlik.org/JA22WK35DD

AMA

1.Arvas A, Çokuğraş H, Gür E, Gönüllü N, Taner Z, Tokman HB. Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey. Balkan Medical Journal. 2017;34(4). https://izlik.org/JA22WK35DD

Chicago

Arvas, Ahmet, Haluk Çokuğraş, Emel Gür, Nevriye Gönüllü, Zeynep Taner, and Hrisi Bahar Tokman. 2017. “Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey”. Balkan Medical Journal 34 (4). https://izlik.org/JA22WK35DD.

EndNote

Arvas A, Çokuğraş H, Gür E, Gönüllü N, Taner Z, Tokman HB (July 1, 2017) Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey. Balkan Medical Journal 34 4

IEEE

[1]A. Arvas, H. Çokuğraş, E. Gür, N. Gönüllü, Z. Taner, and H. B. Tokman, “Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey”, Balkan Medical Journal, vol. 34, no. 4, July 2017, [Online]. Available: https://izlik.org/JA22WK35DD

ISNAD

Arvas, Ahmet - Çokuğraş, Haluk - Gür, Emel - Gönüllü, Nevriye - Taner, Zeynep - Tokman, Hrisi Bahar. “Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey”. Balkan Medical Journal 34/4 (July 1, 2017). https://izlik.org/JA22WK35DD.

JAMA

1.Arvas A, Çokuğraş H, Gür E, Gönüllü N, Taner Z, Tokman HB. Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey. Balkan Medical Journal. 2017;34. Available at https://izlik.org/JA22WK35DD.

MLA

Arvas, Ahmet, et al. “Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey”. Balkan Medical Journal, vol. 34, no. 4, July 2017, https://izlik.org/JA22WK35DD.

Vancouver

1.Ahmet Arvas, Haluk Çokuğraş, Emel Gür, Nevriye Gönüllü, Zeynep Taner, Hrisi Bahar Tokman. Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey. Balkan Medical Journal [Internet]. 2017 Jul. 1;34(4). Available from: https://izlik.org/JA22WK35DD