Is Thrombolytic Therapy Effective in Elderly Patients? Bleeding?

Year 2010, Volume: 2010 Issue: 1, 35 - 38, 01.01.2010

Elena Taneva

Abstract

As the population increases worldwide, the number of elderly patients who present with acute myocardial infarction (AMI) with ST-segment elevation will continue to grow. Thrombolytic therapy (TT) is applied in patients with AMI with ST-segment elevation and aged no more than 75 years. It is recommended percutaneous transluminal coronary angioplasty (PTCA) or by-pass surgery to elderly patients. For PTCA and by-pass surgery there has to be a prepared cardio-surgery medical team, which can be found in big medical hospitals. Patients with AMI with ST-segment elevation over 75 years, which has no TT applied, are with suspicious prognosis for longevity and quality of life. Along with its needed effects TT may cause some unwanted effects such as incidence of major (fatal) or minor bleeding. Dünya çapında nüfus artmakta olduğu için varolan ST segment yükselmeli akut miyokardiyal infarktüsü (AMI) olan yaşlı hasta sayısı da artmaktadır. Trombolitik tedavi (TT) ST segment yükselmeli akut miyokard infarktüsü olan ve 75 yaşından büyük olmayan hastalara uygulanır. Yaşlı hastalara perkutan transluminal koroner anjiyoplasti (PTCA) veya baypas ameliyatı uygulaması önerilir. Perkutan transluminal koroner anjiyoplasti veya baypas ameliyatı için büyük hastanelerde bulunabilen hazırlıklı bir kardiyo-cerrahi ekibi gereklidir. Yetmiş beş yaş üzeri ST segment yükselmeli akut miyokard infarktüsü olan hiç TT uygulanmamış hastaların, yaşam uzunlukları ve kalitelerini tahmin etmek şüphelidir. Trombolitik tedavi istenen etkilerinin yanı sıra büyük (ölümcül) veya küçük kanama gibi istenmeyen etkilere neden olabilir.

Keywords

Elderly, acute myocardial infarction, thrombolytic therapy, bleeding

Trombolitik Tedavi Yaşlı Hastalarda Etkili mi? Kanama?

Abstract

Dünya çapında nüfus artmakta olduğu için varolan ST segment yükselmeli akut miyokardiyal infarktüsü (AMI) olan yaşlı hasta sayısı da artmaktadır. Trombolitik tedavi (TT) ST segment yükselmeli akut miyokard infarktüsü olan ve 75 yaşından büyük olmayan hastalara uygulanır. Yaşlı hastalara perkutan transluminal koroner anjiyoplasti (PTCA) veya baypas ameliyatı uygulaması önerilir. Perkutan transluminal koroner anjiyoplasti veya baypas ameliyatı için büyük hastanelerde bulunabilen hazırlıklı bir kardiyo-cerrahi ekibi gereklidir. Yetmiş beş yaş üzeri ST segment yükselmeli akut miyokard infarktüsü olan hiç TT uygulanmamış hastaların, yaşam uzunlukları ve kalitelerini tahmin etmek şüphelidir. Trombolitik tedavi istenen etkilerinin yanı sıra büyük (ölümcül) veya küçük kanama gibi istenmeyen etkilere neden olabilir.

Keywords

Yaşlı, akut miyokardiyal infarktüsü, trombolik tedavi, kanama

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