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The Alteration of Plasma Atrial Natriuretic Peptide Levels Induced by Postural Changes in Archery Athletes

Year 2010, Volume: 2010 Issue: 4, 275 - 280, 01.04.2010
https://doi.org/10.5174/tutfd.2009.01607.1

Abstract

Objectives: The aim of this study was to investigate plasma atrial natriuretic peptid levels in sitting and supine positions and cardiac functions in young male archery athletes. Materials and Methods: Six archery athletes and 10 sedentary males volunteered to participate in the study. Venous blood samples were taken after 10 minutes sitting and after 10 minutes in supine position. Plasma ANP levels were measured by the ELISA method. Cardiac parameters were assessed by echocardiography. Results: Plasma ANP levels in sitting position were higher in archery athletes (72.12±14.01 pg/ ml) than sedentaries (36.22±14.51 pg/ml; p<0.01). Similarly, plasma ANP levels in supine position (124.41±14.66 pg/ml) were significantly higher in the athletes than sedentaries (36.95±9.83 pg/ml). Plasma ANP levels were higher in supine position than those in sitting position in archery athletes (p<0.01). No significant increase in plasma ANP levels were found in supine position than sitting position in sedentary group. Echocardiographic parameters were similar in athletes and sedentary subjects. Conclusion: It is concluded that regular archery exercises without prominent functional and morphological alterations in the heart may cause differences in plasma ANP levels. Marked posture-related alterations may occur in plasma ANP levels of trained archery athletes. Amaç: Bu çalışmanın amacı, okçuluk sporu yapan genç erkek sporcuların plazma atriyal natriüretik peptid (ANP) düzeylerinde oturur ve yatar durumdaki değişimi ve kardiyak fonksiyonlarını incelemektir. Gereçler ve Yöntemler: Çalışmaya, gönüllü 6 okçuluk sporcusu ve 10 sedanter erkek katıldı. Katılımcılardan 10 dk'lık oturma sonrası ve 10 dk'lık yatar durumdan sonra venöz kan alındı. Plazma ANP düzeyleri ELISA yöntemi ile ölçüldü. Kardiyak parametreler ekokardiyografi ile belirlendi. Bulgular: Okçuluk sporcularının oturur durumdaki plazma ANP düzeylerinin (72.12±14.01 pg/ml) sedanter grubun oturur durumdaki ANP düzeylerinden (36.22±14.51 pg/ml) yüksek olduğu bulundu (p<0.01). Aynı şekilde okçuluk sporcularının yatar durumdaki ANP düzeyleri de (124.41±14.66 pg/ml) sedanterlere göre (36.95±9.83 pg/ml) anlamlı yükseklik gösterdi (p<0.01). Sporcu grubun plazma ANP düzeyleri oturur duruma göre yatar durumda artmış bulundu (p<0.01). Sedanter grubun ANP düzeylerinde ise oturur duruma göre yatar durumda anlamlı bir artış saptanmadı. Sporcu ve sedanterlerin ekokardiyografik parametreleri benzer bulundu. Sonuç: Çalışmamıza göre okçulukla ilgili yapılan düzenli egzersizler, kalpte belirgin fonksiyonel ve morfolojik değişim olmaksızın, plazma ANP düzeylerinde farklılıklara neden olabilir. Okçuluk sporu yapanların plazma ANP düzeyinde postürle ilişkili belirgin farklılıklar oluşabilir.

References

  • Garbers DL, Koesling D, Schultz G. Guanylyl cyclase recep- tors. Mol Biol Cell 1994;5:1-5.
  • Stults JT, O'Connell KL, Garcia C, Wong S, Engel AM, Garbers DL, et al. The disulfide linkages and glycosylation sites of the human natriuretic peptide receptor-C homodi- mer. Biochemistry 1994;33:11372-81.
  • Horio T, Nishikimi T, Yoshihara F, Matsuo H, Takishita S, Kangawa K. Inhibitory regulation of hypertrophy by endogenous atrial natriuretic peptide in cultured cardiac myocytes. Hypertension 2000;35:19-24.
  • John SW, Krege JH, Oliver PM, Hagaman JR, Hodgin JB, Pang SC, et al. Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension. Science 1995;267:679-81.
  • Thamsborg G, Sykulski R, Larsen J, Storm T, Keller N. Effect of beta 1-adrenoceptor blockade on plasma levels of atrial natriuretic peptide during exercise in normal man. Clin Physiol 1987;7:313-8.
  • Saito Y, Nakao K, Sugawara A, Nishimura K, Sakamoto M, Morii N, et al. Atrial natriuretic polypeptide during exercise in healthy man. Acta Endocrinol 1987;116:59-65.
  • Saito Y, Nakao K, Sugawara A, Nishimura K, Morii N, Yamada T, et al. Exaggerated secretion of atrial natriuretic polypeptide during dynamic exercise in patients with essential hypertension. Am Heart J 1988;116:1052-7.
  • Mannix ET, Palange P, Aronoff GR, Manfredi F, Farber MO. Atrial natriuretic peptide and the renin-aldosterone axis during exercise in man. Med Sci Sports Exerc 1990;22:785-9.
  • Mandroukas K, Zakas A, Aggelopoulou N, Christoulas K, Abatzides G, Karamouzis M. Atrial natriuretic factor responses to submaximal and maximal exercise. Br J Sports Med 1995;29:248-51.
  • Alexiou S, Kouidi E, Fahadidou-Tsiligiroglou A, Karamouzis M, Deligiannis A. Cardiac function after exhaustive open- sea swimming. J Sports Med Phys Fitness 2005;45:98-104.
  • Burnett JC Jr, Kao PC, Hu DC, Heser DW, Heublein D, Granger JP, et al. Atrial natriuretic peptide elevation in con- gestive heart failure in the human. Science 1986;231:1145-7.
  • Nishikimi T, Morimoto A, Ishikawa K, Saito Y, Kangawa K, Matsuo H, et al. Different secretion patterns of adreno- medullin, brain natriuretic peptide, and atrial natriuretic peptide during exercise in hypertensive and normotensive subjects. Clin Exp Hypertens 1997;19:503-18.
  • Vogelsang TW, Yoshiga CC, Hİjgaard M, Kjaer A, Warberg J, Secher NH, et al. The plasma atrial natriuretic peptide response to arm and leg exercise in humans: effect of pos- ture. Exp Physiol 2006;91:765-71.
  • George KP, Wolfe LA, Burggraf GW. The 'athletic heart syn- drome'. A critical review. Sports Med 1991;11:300-30.
  • Whyte GP, George K, Nevill A, Shave R, Sharma S, McKenna WJ. Left ventricular morphology and func- tion in female athletes: a meta-analysis. Int J Sports Med 2004;25:380-3.
  • Tsai RC, Yamaji T, Ishibashi M, Takaku F, Hsu ST, Yeh SJ, et al. Role of atrial natriuretic peptide in hemoconcentration during exercise. Am J Hypertens 1990;3:833-7.
  • Astrand PO, Ryhming I. A nomogram for calculation of aerobic capacity (physical fitness) from pulse rate during sub-maximal work. J Appl Physiol 1954;7:218-21.
  • Astrand I. Aerobic work capacity in men and women with special reference to age. Acta Physiol Scand Suppl 1960;49:1-92.
  • Rost R, Hollmann W. Athlete's heart--a review of its historical assessment and new aspects. Int J Sports Med 1983;4:147-65.
  • Barbier J, Lebiller E, Ville N, Rannou-Bekono F, Carré F. Relationships between sports-specific characteristics of ath- lete's heart and maximal oxygen uptake. Eur J Cardiovasc Prev Rehabil 2006;13:115-21.
  • Naylor LH, George K, O'Driscoll G, Green DJ. The athlete's heart: a contemporary appraisal of the 'Morganroth hypoth- esis'. Sports Med 2008;38:69-90.
  • Morganroth J, Maron BJ, Henry WL, Epstein SE. Comparative left ventricular dimensions in trained athletes. Ann Intern Med 1975;82:521-4.
  • Barbier J, Ville N, Kervio G, Walther G, Carré F. Sports- specific features of athlete's heart and their relation to echo- cardiographic parameters. Herz 2006;31:531-43.
  • Ohba H, Takada H, Musha H, Nagashima J, Mori N, Awaya T, et al. Effects of prolonged strenuous exercise on plasma levels of atrial natriuretic peptide and brain natriuretic pep- tide in healthy men. Am Heart J 2001;141:751-8.
  • Date H, Imamura T, Onitsuka H, Maeno M, Watanabe R, Nishihira K, et al. Differential increase in natriuret- ic peptides in elite dynamic and static athletes. Circ J 2003;67:691-6.
  • Cao L, Gardner DG. Natriuretic peptides inhibit DNA syn- thesis in cardiac fibroblasts. Hypertension 1995;25:227-34.
  • Wada A, Tsutamoto T, Matsuda Y, Kinoshita M. Cardiorenal and neurohumoral effects of endogenous atrial natriuretic peptide in dogs with severe congestive heart failure using a specific antagonist for guanylate cyclase-coupled receptors. Circulation 1994;89:2232-40.
  • Zolty R, Bauer C, Allen P, Garrity M, Vittorio TJ. Atrial natriuretic peptide stability. Clin Biochem 2008;41:1255-8.
  • Mitchell JH, Haskell WL, Raven PB. Classification of sports. Med Sci Sports Exerc 1994;26(10 Suppl):S242-5.
  • Olgun H, Özer S. Genç sporcularda aritmi ve ani ölüm. Hacettepe Tıp Dergisi 2006;37:132-41.
  • Wieling W, Borghols EA, Hollander AP, Danner SA, Dunning AJ. Echocardiographic dimensions and maximal oxygen uptake in oarsmen during training. Br Heart J 1981;46:190-5.
  • Heringlake M, Heide C, Bahlmann L, Eichler W, Pagel H, Schmucker P, et al. Effects of tilting and volume loading on plasma levels and urinary excretion of relaxin, NT-pro- ANP, and NT-pro-BNP in male volunteers. J Appl Physiol 2004;97:173-9.

Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi

Year 2010, Volume: 2010 Issue: 4, 275 - 280, 01.04.2010
https://doi.org/10.5174/tutfd.2009.01607.1

Abstract

Amaç: Bu çalışmanın amacı, okçuluk sporu yapan
genç erkek sporcuların plazma atriyal natriüretik
peptid (ANP) düzeylerinde oturur ve yatar durumdaki
değişimi ve kardiyak fonksiyonlarını incelemektir.
Gereçler ve Yöntemler: Çalışmaya, gönüllü
6 okçuluk sporcusu ve 10 sedanter erkek katıldı.
Katılımcılardan 10 dk’lık oturma sonrası ve 10 dk’lık
yatar durumdan sonra venöz kan alındı. Plazma ANP
düzeyleri ELISA yöntemi ile ölçüldü. Kardiyak parametreler
ekokardiyografi ile belirlendi.
Bulgular: Okçuluk sporcularının oturur durumdaki
plazma ANP düzeylerinin (72.12±14.01 pg/ml) sedanter
grubun oturur durumdaki ANP düzeylerinden
(36.22±14.51 pg/ml) yüksek olduğu bulundu (p < 0.01).
Aynı şekilde okçuluk sporcularının yatar durumdaki
ANP düzeyleri de (124.41±14.66 pg/ml) sedanterlere
göre (36.95±9.83 pg/ml) anlamlı yükseklik gösterdi
(p < 0.01). Sporcu grubun plazma ANP düzeyleri oturur
duruma göre yatar durumda artmış bulundu (p < 0.01).
Sedanter grubun ANP düzeylerinde ise oturur duruma
göre yatar durumda anlamlı bir artış saptanmadı.
Sporcu ve sedanterlerin ekokardiyografik parametreleri
benzer bulundu.
Sonuç: Çalışmamıza göre okçulukla ilgili yapılan
düzenli egzersizler, kalpte belirgin fonksiyonel ve
morfolojik değişim olmaksızın, plazma ANP düzeylerinde
farklılıklara neden olabilir. Okçuluk sporu yapanların
plazma ANP düzeyinde postürle ilişkili belirgin
farklılıklar oluşabilir.

References

  • Garbers DL, Koesling D, Schultz G. Guanylyl cyclase recep- tors. Mol Biol Cell 1994;5:1-5.
  • Stults JT, O'Connell KL, Garcia C, Wong S, Engel AM, Garbers DL, et al. The disulfide linkages and glycosylation sites of the human natriuretic peptide receptor-C homodi- mer. Biochemistry 1994;33:11372-81.
  • Horio T, Nishikimi T, Yoshihara F, Matsuo H, Takishita S, Kangawa K. Inhibitory regulation of hypertrophy by endogenous atrial natriuretic peptide in cultured cardiac myocytes. Hypertension 2000;35:19-24.
  • John SW, Krege JH, Oliver PM, Hagaman JR, Hodgin JB, Pang SC, et al. Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension. Science 1995;267:679-81.
  • Thamsborg G, Sykulski R, Larsen J, Storm T, Keller N. Effect of beta 1-adrenoceptor blockade on plasma levels of atrial natriuretic peptide during exercise in normal man. Clin Physiol 1987;7:313-8.
  • Saito Y, Nakao K, Sugawara A, Nishimura K, Sakamoto M, Morii N, et al. Atrial natriuretic polypeptide during exercise in healthy man. Acta Endocrinol 1987;116:59-65.
  • Saito Y, Nakao K, Sugawara A, Nishimura K, Morii N, Yamada T, et al. Exaggerated secretion of atrial natriuretic polypeptide during dynamic exercise in patients with essential hypertension. Am Heart J 1988;116:1052-7.
  • Mannix ET, Palange P, Aronoff GR, Manfredi F, Farber MO. Atrial natriuretic peptide and the renin-aldosterone axis during exercise in man. Med Sci Sports Exerc 1990;22:785-9.
  • Mandroukas K, Zakas A, Aggelopoulou N, Christoulas K, Abatzides G, Karamouzis M. Atrial natriuretic factor responses to submaximal and maximal exercise. Br J Sports Med 1995;29:248-51.
  • Alexiou S, Kouidi E, Fahadidou-Tsiligiroglou A, Karamouzis M, Deligiannis A. Cardiac function after exhaustive open- sea swimming. J Sports Med Phys Fitness 2005;45:98-104.
  • Burnett JC Jr, Kao PC, Hu DC, Heser DW, Heublein D, Granger JP, et al. Atrial natriuretic peptide elevation in con- gestive heart failure in the human. Science 1986;231:1145-7.
  • Nishikimi T, Morimoto A, Ishikawa K, Saito Y, Kangawa K, Matsuo H, et al. Different secretion patterns of adreno- medullin, brain natriuretic peptide, and atrial natriuretic peptide during exercise in hypertensive and normotensive subjects. Clin Exp Hypertens 1997;19:503-18.
  • Vogelsang TW, Yoshiga CC, Hİjgaard M, Kjaer A, Warberg J, Secher NH, et al. The plasma atrial natriuretic peptide response to arm and leg exercise in humans: effect of pos- ture. Exp Physiol 2006;91:765-71.
  • George KP, Wolfe LA, Burggraf GW. The 'athletic heart syn- drome'. A critical review. Sports Med 1991;11:300-30.
  • Whyte GP, George K, Nevill A, Shave R, Sharma S, McKenna WJ. Left ventricular morphology and func- tion in female athletes: a meta-analysis. Int J Sports Med 2004;25:380-3.
  • Tsai RC, Yamaji T, Ishibashi M, Takaku F, Hsu ST, Yeh SJ, et al. Role of atrial natriuretic peptide in hemoconcentration during exercise. Am J Hypertens 1990;3:833-7.
  • Astrand PO, Ryhming I. A nomogram for calculation of aerobic capacity (physical fitness) from pulse rate during sub-maximal work. J Appl Physiol 1954;7:218-21.
  • Astrand I. Aerobic work capacity in men and women with special reference to age. Acta Physiol Scand Suppl 1960;49:1-92.
  • Rost R, Hollmann W. Athlete's heart--a review of its historical assessment and new aspects. Int J Sports Med 1983;4:147-65.
  • Barbier J, Lebiller E, Ville N, Rannou-Bekono F, Carré F. Relationships between sports-specific characteristics of ath- lete's heart and maximal oxygen uptake. Eur J Cardiovasc Prev Rehabil 2006;13:115-21.
  • Naylor LH, George K, O'Driscoll G, Green DJ. The athlete's heart: a contemporary appraisal of the 'Morganroth hypoth- esis'. Sports Med 2008;38:69-90.
  • Morganroth J, Maron BJ, Henry WL, Epstein SE. Comparative left ventricular dimensions in trained athletes. Ann Intern Med 1975;82:521-4.
  • Barbier J, Ville N, Kervio G, Walther G, Carré F. Sports- specific features of athlete's heart and their relation to echo- cardiographic parameters. Herz 2006;31:531-43.
  • Ohba H, Takada H, Musha H, Nagashima J, Mori N, Awaya T, et al. Effects of prolonged strenuous exercise on plasma levels of atrial natriuretic peptide and brain natriuretic pep- tide in healthy men. Am Heart J 2001;141:751-8.
  • Date H, Imamura T, Onitsuka H, Maeno M, Watanabe R, Nishihira K, et al. Differential increase in natriuret- ic peptides in elite dynamic and static athletes. Circ J 2003;67:691-6.
  • Cao L, Gardner DG. Natriuretic peptides inhibit DNA syn- thesis in cardiac fibroblasts. Hypertension 1995;25:227-34.
  • Wada A, Tsutamoto T, Matsuda Y, Kinoshita M. Cardiorenal and neurohumoral effects of endogenous atrial natriuretic peptide in dogs with severe congestive heart failure using a specific antagonist for guanylate cyclase-coupled receptors. Circulation 1994;89:2232-40.
  • Zolty R, Bauer C, Allen P, Garrity M, Vittorio TJ. Atrial natriuretic peptide stability. Clin Biochem 2008;41:1255-8.
  • Mitchell JH, Haskell WL, Raven PB. Classification of sports. Med Sci Sports Exerc 1994;26(10 Suppl):S242-5.
  • Olgun H, Özer S. Genç sporcularda aritmi ve ani ölüm. Hacettepe Tıp Dergisi 2006;37:132-41.
  • Wieling W, Borghols EA, Hollander AP, Danner SA, Dunning AJ. Echocardiographic dimensions and maximal oxygen uptake in oarsmen during training. Br Heart J 1981;46:190-5.
  • Heringlake M, Heide C, Bahlmann L, Eichler W, Pagel H, Schmucker P, et al. Effects of tilting and volume loading on plasma levels and urinary excretion of relaxin, NT-pro- ANP, and NT-pro-BNP in male volunteers. J Appl Physiol 2004;97:173-9.
There are 32 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Selma Arzu Vardar This is me

Meryem Aktoz This is me

Özgül Karakuşoğlu This is me

Hakan Kunduracılar This is me

Publication Date April 1, 2010
Published in Issue Year 2010 Volume: 2010 Issue: 4

Cite

APA Vardar, S. A., Aktoz, M., Karakuşoğlu, Ö., Kunduracılar, H. (2010). Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi. Balkan Medical Journal, 2010(4), 275-280. https://doi.org/10.5174/tutfd.2009.01607.1
AMA Vardar SA, Aktoz M, Karakuşoğlu Ö, Kunduracılar H. Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi. Balkan Medical Journal. April 2010;2010(4):275-280. doi:10.5174/tutfd.2009.01607.1
Chicago Vardar, Selma Arzu, Meryem Aktoz, Özgül Karakuşoğlu, and Hakan Kunduracılar. “Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi”. Balkan Medical Journal 2010, no. 4 (April 2010): 275-80. https://doi.org/10.5174/tutfd.2009.01607.1.
EndNote Vardar SA, Aktoz M, Karakuşoğlu Ö, Kunduracılar H (April 1, 2010) Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi. Balkan Medical Journal 2010 4 275–280.
IEEE S. A. Vardar, M. Aktoz, Ö. Karakuşoğlu, and H. Kunduracılar, “Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi”, Balkan Medical Journal, vol. 2010, no. 4, pp. 275–280, 2010, doi: 10.5174/tutfd.2009.01607.1.
ISNAD Vardar, Selma Arzu et al. “Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi”. Balkan Medical Journal 2010/4 (April 2010), 275-280. https://doi.org/10.5174/tutfd.2009.01607.1.
JAMA Vardar SA, Aktoz M, Karakuşoğlu Ö, Kunduracılar H. Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi. Balkan Medical Journal. 2010;2010:275–280.
MLA Vardar, Selma Arzu et al. “Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi”. Balkan Medical Journal, vol. 2010, no. 4, 2010, pp. 275-80, doi:10.5174/tutfd.2009.01607.1.
Vancouver Vardar SA, Aktoz M, Karakuşoğlu Ö, Kunduracılar H. Okçuluk Sporcularında Plazma Atriyal Natriüretik Peptid Düzeyinin Postüre Bağlı Değişimi. Balkan Medical Journal. 2010;2010(4):275-80.