Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis

Ekrem Güler; Şeref Olgar; Mehmet Davutoğlu; Mesut Garipardıç; Hamza Karabiber

doi:10.5174/tutfd.2009.02691.1

Research Article

Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis

Year 2011, Volume: 2011 Issue: 2, 212 - 213, 01.02.2011

Ekrem Güler Şeref Olgar Mehmet Davutoğlu Mesut Garipardıç Hamza Karabiber

https://doi.org/10.5174/tutfd.2009.02691.1

Abstract

Benzalkonium chloride (BAC) is a frequently used disinfectant and its most well-known side effect is contact dermatitis. In this report, two children who had vesicular dermatitis, headache, lethargy, fever and encephalopathy mimicking Herpes zoster encephalitis were presented. Their consciousness level improved on the second day. From the medical history it was understood that the mother had applied 20% BAC solution to the scalps of two children. The aim of the presentation of this report is to draw attention to the fact that BAC application to the scalp for treating pediculosis capitis may resemble the herpes encephalitis clinical picture.

Keywords

Benzalkonium chloride, encephalopathy, intoxication, Herpes zoster mimicking encephalopathy, vesicular contact dermatitis

References

1. Johnston MV. Encephalopathies. In: Behrman RE, Kliegman RM, Arvin AM, eds. Nelson Textbook of Pediatrics. 17th edition. Philadelphia: WB Saunders 2003;2023-9.
2. Richard J. Whitley; Viral infections of the central nervous system. In: Gershon AA, Hotez PJ, Katz SL, eds. Krugman’s Infectious Diseases of Children. 11th edition. St Louis: Mosby 2003;855-76.
3. Myers MG, Stanberry LR, Seward JF. Varicella-Zoster Virus. In: Behrman RE, Kliegman RM, Arvin AM, eds. Nelson Textbook of Pediatrics. 17th edition. Philadelphia: WB Saunders, 2003;1057-62.
4. Sigaloff KC, de Fijter CW. Herpes zoster-associated encephalitis in a patient undergoing CAPD: case report and literature review. Perit Dial Int 2007;27:391-4.
5. Deutschle T, Porkert U, Reiter R, Keck T, Riechelmann H. In vitro genotoxicity and cytotoxicity of benzalkonium chloride. Toxicol in Vitro 2006;20:1472-7. [CrossRef]
6. Bernstein IL. Is the use of benzalkonium chloride as a preservative for nasal formulations a safety concern? A cautionary note based on compromised mucociliary transport. J Allergy Clin Immunol 2000;105:39-44. [CrossRef]
7. Gurol Y, Kocagoz S. Comparasion of the effi cacy of two new disinfectants with other disinfectants. Turkiye Klinikleri J Med Sci 2008;28:128-32.
8. Fuchs T, Meinert A, Aberer W, Bahmer FA, Peters KP, Lischka GG, Schulze-Dirks A, Enders F, Frosch PJ. Benzalkonium chloride--a relevant contact allergen or irritant? Results of a multicenter study of the German Contact Allergy Group. Hautarzt 1993;44:699-702.
9. http://www.vetas.com.tr/dokumanlar/1189846868.pdf [CrossRef]

Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis

Year 2011, Volume: 2011 Issue: 2, 212 - 213, 01.02.2011

Ekrem Güler Şeref Olgar Mehmet Davutoğlu Mesut Garipardıç Hamza Karabiber

https://doi.org/10.5174/tutfd.2009.02691.1

Abstract

References

1. Johnston MV. Encephalopathies. In: Behrman RE, Kliegman RM, Arvin AM, eds. Nelson Textbook of Pediatrics. 17th edition. Philadelphia: WB Saunders 2003;2023-9.
2. Richard J. Whitley; Viral infections of the central nervous system. In: Gershon AA, Hotez PJ, Katz SL, eds. Krugman’s Infectious Diseases of Children. 11th edition. St Louis: Mosby 2003;855-76.
3. Myers MG, Stanberry LR, Seward JF. Varicella-Zoster Virus. In: Behrman RE, Kliegman RM, Arvin AM, eds. Nelson Textbook of Pediatrics. 17th edition. Philadelphia: WB Saunders, 2003;1057-62.
4. Sigaloff KC, de Fijter CW. Herpes zoster-associated encephalitis in a patient undergoing CAPD: case report and literature review. Perit Dial Int 2007;27:391-4.
5. Deutschle T, Porkert U, Reiter R, Keck T, Riechelmann H. In vitro genotoxicity and cytotoxicity of benzalkonium chloride. Toxicol in Vitro 2006;20:1472-7. [CrossRef]
6. Bernstein IL. Is the use of benzalkonium chloride as a preservative for nasal formulations a safety concern? A cautionary note based on compromised mucociliary transport. J Allergy Clin Immunol 2000;105:39-44. [CrossRef]
7. Gurol Y, Kocagoz S. Comparasion of the effi cacy of two new disinfectants with other disinfectants. Turkiye Klinikleri J Med Sci 2008;28:128-32.
8. Fuchs T, Meinert A, Aberer W, Bahmer FA, Peters KP, Lischka GG, Schulze-Dirks A, Enders F, Frosch PJ. Benzalkonium chloride--a relevant contact allergen or irritant? Results of a multicenter study of the German Contact Allergy Group. Hautarzt 1993;44:699-702.
9. http://www.vetas.com.tr/dokumanlar/1189846868.pdf [CrossRef]

There are 9 citations in total.

Details

Primary Language	English
Subjects	Health Care Administration
Journal Section	Articles
Authors	Ekrem Güler This is me Şeref Olgar This is me Mehmet Davutoğlu This is me Mesut Garipardıç This is me Hamza Karabiber This is me
Publication Date	February 1, 2011
Published in Issue	Year 2011 Volume: 2011 Issue: 2

Cite

APA	Güler, E., Olgar, Ş., Davutoğlu, M., Garipardıç, M., et al. (2011). Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis. Balkan Medical Journal, 2011(2), 212-213. https://doi.org/10.5174/tutfd.2009.02691.1
AMA	Güler E, Olgar Ş, Davutoğlu M, Garipardıç M, Karabiber H. Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis. Balkan Medical Journal. February 2011;2011(2):212-213. doi:10.5174/tutfd.2009.02691.1
Chicago	Güler, Ekrem, Şeref Olgar, Mehmet Davutoğlu, Mesut Garipardıç, and Hamza Karabiber. “Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis”. Balkan Medical Journal 2011, no. 2 (February 2011): 212-13. https://doi.org/10.5174/tutfd.2009.02691.1.
EndNote	Güler E, Olgar Ş, Davutoğlu M, Garipardıç M, Karabiber H (February 1, 2011) Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis. Balkan Medical Journal 2011 2 212–213.
IEEE	E. Güler, Ş. Olgar, M. Davutoğlu, M. Garipardıç, and H. Karabiber, “Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis”, Balkan Medical Journal, vol. 2011, no. 2, pp. 212–213, 2011, doi: 10.5174/tutfd.2009.02691.1.
ISNAD	Güler, Ekrem et al. “Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis”. Balkan Medical Journal 2011/2 (February 2011), 212-213. https://doi.org/10.5174/tutfd.2009.02691.1.
JAMA	Güler E, Olgar Ş, Davutoğlu M, Garipardıç M, Karabiber H. Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis. Balkan Medical Journal. 2011;2011:212–213.
MLA	Güler, Ekrem et al. “Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis”. Balkan Medical Journal, vol. 2011, no. 2, 2011, pp. 212-3, doi:10.5174/tutfd.2009.02691.1.
Vancouver	Güler E, Olgar Ş, Davutoğlu M, Garipardıç M, Karabiber H. Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis. Balkan Medical Journal. 2011;2011(2):212-3.