Extragenital Müllerian Adenosarcoma in the Pouch of Douglas

Year 2014, Volume: 2014 Issue: 1, 100 - 104, 07.08.2014

Ateş Karateke İlker Kahramanoğlu Remziye Bilgiç

https://doi.org/10.5152/balkanmedj.2013.9065

Abstract

Background: Extragenital Müllerian adenosarcomas are extremely rare tumours characterised by a stromal component of low-grade malignancy and by a benign glandular epithelial component. Case Report: A 26-year-old woman was admitted to our clinic because of lower abdominal distension and left lower quadrant pain. Clinical and radiological examinations suggested an ovarian malignancy. Laparotomy revealed a cystic mass in the pouch of Douglas, originating from the left sacrouterine ligament. A total excision of the tumour was performed and showed low-grade adenosarcoma without sarcomatous overgrowth. Follow-up at 24 months after the surgery showed no evidence of recurrence. Conclusion: Mullerian adenosarcoma located in the pouch of Douglas is rare. For treatment, success may be achieved with only excision of the tumour if there is no sarcomatous overgrowth or spread to adjacent tissues.

Keywords

Adenosarcoma, adnexal, Douglas, extragenital, Müllerian, tumour

Extragenital Müllerian Adenosarcoma in the Pouch of Douglas

Abstract

Keywords

xx

References

• Clement PB, Scully RE. Müllerian adenosarcoma of the uterus. A clinicopathologic analysis of ten cases of a distinctive type of Müllerian mixed tumor. Cancer 1974;34:1138-49. [CrossRef]
• Inoue M, Fukuda H, Tanizawa O. Adenosarcomas originating from sites other than uterine endometrium. Int J Gynaecol Obstet 1995;48: 299-30 [CrossRef]
• Visvalingam S, Jaworski R, Blumenthal N, Chan F. Primary peritoneal mesodermal adenosarcoma: report of a case and review of the literature. Gynecol Oncol 2001;81:500-5. [CrossRef]
• Toyoshima M, Akahira J, Moriya T, Hayakawa S, Yaegashi N. Primary vaginal adenosarcoma with sarcomatous overgrowth. Gynecol Oncol 2004;95:759-61. [CrossRef]
• Ostör AG, Nirenberg A, Ashdown ML, Murphy DJ. Extragenital adenosarcoma arising in the pouch of Douglas. Gynecol Oncol 1994;53:373-5. [CrossRef]
• Patrelli TS, Silini EM, Gizzo S, Berretta R, Franchi L, Thai E, et al. Extragenital Müllerian adenosarcoma with pouch of Douglas location. BMC Cancer 2011;15;11:171.
• Clement PB, Scully RE. Extra uterine mesodermal (müllerian) adenosarcoma:a clinicopathologic analysis of five cases. Am J Clin Pathol 1978;69:276-83.
• Murugasu A, Miller J, Proietto A, Millar E. Extragenital Mullerian adenosarcoma with sarcomatous overgrowth arising in an endometriotic cyst in the pouch of Douglas. Int J Gynecol Cancer 2003;13:371-5. [CrossRef] Chang HY, Changchien CC, Chen HH, Lin H, Huang CC. Extrauterine Mullerian adenosarcoma associated with endometriosis and rectal villotubular adenoma: report of a case and review of the literature. Int J Gynecol Cancer 2005;15:361-5. [CrossRef]
• Huang GS, Arend RC, Sakaris A, Hebert TM, Goldberg GL. Extragenital adenosarcoma:A case report, review of the literature, and management discussion. Gynecol Oncol 2009;115:472-5. [CrossRef]
• Douglas GW, Kastin AJ, Huntington RW. Carcinoma arising in a retroperitonel Mullerian cyst with widespread metastases during pregnancy. Am J Obstet Gynecol 1965;91:210-6.
• Bard E, Bard D, Vargas-Cortez F. Extrauterine Mullerian Adenosarcoma. A clinicopathologic report of a case with distant metastases and a review of the literature. Gynecol Oncol 1978;6:271-4. [CrossRef]
• Kao GF, Norris HJ. Benign and low grade variants of mixed mesodermal tumour (6. adenosarcoma) of the ovary and adnexal region. Cancer 1978;42:1314-24. [CrossRef]
• Russel P, Slavutin R, Laverty CR, Cooper J. Extrauterine mesodermal (Mullerian) adenosarcoma. A case report. Pathology 1979;11:557-60. [CrossRef]
• Vara AR, Ruzics EP, Moussabeck O, Martin DC. Endometroid adenosarcoma of the bladder arising from endometriosis. J Urol 1990;143:813-5.