A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis

Year 2014, Volume: 31 Issue: 4, 356 - 359, 01.10.2014

Arbil Açıkalın Aysun Uğuz Derya Gümürdülü Semra Paydaş Ümran Küçükgöz Güleç

Abstract

Background: Merkel cell carcinoma (MCC) is a rare cutaneous/mucosal
malignancy with very aggressive biology and increasing incidence.
Ovarian metastasis is an exceptionally rare site for MCC, and
only two cases have been reported in the literature.
Case Report: We report MCC with ovarian metastasis. A 34
year-old female with previously excised MCC from preauricular
skin presented with a pelvic mass 15 months after first diagnosis.
Anti-cytokeratin (CK) 20 positivity, LCA (leucocyte common antigen), and TTF-1 (Thyroid transcription factor-1)
negativity confirmed metastatic ovarian MCC. There was no evidence
of recurrence or metastasis at 12 months after salpingooopherectomy.
Conclusion: MCC should be considered in the differential diagnosis
of primary and metastatic undifferentiated small round cell tumors
of the ovary.

Keywords

Carcinoma, Merkel cell, metastasis ovarian, neoplasms

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