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Year 2017, Volume: 34 Issue: 4, 367 - 370, 01.07.2017

Abstract

References

  • 1. Mohapatra B, Warrell DA, Suraweera W, Bhatia P, Dhingra N, Jotkar RM, et al. Snakebite mortality in India: a Nationally representative mortality survey. Plos Negl Trop Dis 2011;5:e1018.
  • 2. Spiller HA, Bosse GM. Prospective study of morbidity associated with snakebite envenomation. J Toxicol Clin Toxicol 2003;41:125-30.
  • 3. Tucker SC, Josty I. Compartment syndrome in the hand following an adder bite. J Hand Surg Br 2005;30:434-5.
  • 4. Downey DJ, Omer GE, Moneim MS. New Mexico rattlesnake bites: demographic review and guidelines for treatment. J Trauma 1991;31:1380- 6.
  • 5. Cortelazzo A, Guerranti R, Bini L, Hope-Onyekwere N, Muzzi C, Leoncini R, et al. Effects of snake venom proteases on human fibrinogen chains. Blood Transfus 2010;8:120-5.
  • 6. Thomas L, Tyburn B, Bucher B, Pecout F, Ketterle J, Rieux D, et al. Prevention of thromboses in human patients with Bothrops lanceolatus envenoming in Martinique: failure of anticoagulants and efficacy of a monospecific antivenom. Research Group on Snake Bites in Martinique. Am J Trop Med Hyg 1995;52:419-26.
  • 7. Dagda RK, Gasanov S, De La Oiii Y, Rael ED, Lieb C. Genetic basis for variation of metalloproteinase-associated biochemical activity in venom of the Mojave rattlesnake (Crotalus scutulatus). Biochem Rest Int 2013;2013:251474.
  • 8. Massey DJ, Calvete JJ, Sanchez EE, Sanz L, Richards K, Curtis R et al. Venom variability and envenoming severity outcomes of the Crotalus scutulatus (Mojave rattlesnake) from southern Arizona. J Proteomics 2012;75:2576-87.
  • 9. Dagda RK, Gasanov SE, Zhang B, Welch W, Rael ED. Molecular models of the Mojave rattlesnake (Crotalus scutulatus scutulatus) venom metalloproteinases reveal a structural basis for differences in hemorrhagic activities. J Biol Phys 2014;40:193-216.
  • 10. Natarajan N, Basheer A, Mookkappan S, Periyasamy S. Reversible lower limb deep vein thrombosis following haemotoxic snakebite-a case report. AMJ 2014;7:232-5.

The Compartment Syndrome Associated with Deep Vein Thrombosis due to Rattlesnake Bite: A Case Report

Year 2017, Volume: 34 Issue: 4, 367 - 370, 01.07.2017

Abstract

Background: Snakebite is a health issue specific to some parts of the world, especially in the tropical area, where it produces many victims. The main clinical damage caused by snake bite involves hemotoxic, neurotoxic and myotoxic reactions. It is also established that the importance of systemic impairment varies according to individual factors and are related to organ dysfunction, shock or hypotension. We report the case of a young woman suffering from snakebite who developed deep vein thrombosis and compartment syndrome. Case Report: We present the case of a 32-year-old Romanian woman who was injured by her own Crotalinae snake (also known as pit viper or rattlesnake) on her left forearm. When admitted to our Emergency Department, she was conscious with a Glasgow coma scale of 12/15, somnolent, febrile, suffering of headache, tachypnea; the marks of the snakebite were located in the distal part of the anterior left forearm; she had pain and bleeding at the bite site and swelling of the left upper limb with lymphangitis up to the axilla. She experienced fasciotomy-requiring compartment syndrome of the upper limb and required unfractionated heparin and closed monitored using activated partial thromboplastin time evolution due micro-thrombosis in the brachial vein. Local improvement was achieved in the next 4 days with progressive diminish of local tenderness and swelling. Conclusion: Limb deep vein thrombosis might be induced by snakebite, despite pro-hemorrhagic general condition induced by the envenomation. High index of clinical suspicion is needed for early diagnosis and timely management which can improve survival of these patients. Keywords: Snakebite, developed deep vein thrombosis, compartment syndrome

References

  • 1. Mohapatra B, Warrell DA, Suraweera W, Bhatia P, Dhingra N, Jotkar RM, et al. Snakebite mortality in India: a Nationally representative mortality survey. Plos Negl Trop Dis 2011;5:e1018.
  • 2. Spiller HA, Bosse GM. Prospective study of morbidity associated with snakebite envenomation. J Toxicol Clin Toxicol 2003;41:125-30.
  • 3. Tucker SC, Josty I. Compartment syndrome in the hand following an adder bite. J Hand Surg Br 2005;30:434-5.
  • 4. Downey DJ, Omer GE, Moneim MS. New Mexico rattlesnake bites: demographic review and guidelines for treatment. J Trauma 1991;31:1380- 6.
  • 5. Cortelazzo A, Guerranti R, Bini L, Hope-Onyekwere N, Muzzi C, Leoncini R, et al. Effects of snake venom proteases on human fibrinogen chains. Blood Transfus 2010;8:120-5.
  • 6. Thomas L, Tyburn B, Bucher B, Pecout F, Ketterle J, Rieux D, et al. Prevention of thromboses in human patients with Bothrops lanceolatus envenoming in Martinique: failure of anticoagulants and efficacy of a monospecific antivenom. Research Group on Snake Bites in Martinique. Am J Trop Med Hyg 1995;52:419-26.
  • 7. Dagda RK, Gasanov S, De La Oiii Y, Rael ED, Lieb C. Genetic basis for variation of metalloproteinase-associated biochemical activity in venom of the Mojave rattlesnake (Crotalus scutulatus). Biochem Rest Int 2013;2013:251474.
  • 8. Massey DJ, Calvete JJ, Sanchez EE, Sanz L, Richards K, Curtis R et al. Venom variability and envenoming severity outcomes of the Crotalus scutulatus (Mojave rattlesnake) from southern Arizona. J Proteomics 2012;75:2576-87.
  • 9. Dagda RK, Gasanov SE, Zhang B, Welch W, Rael ED. Molecular models of the Mojave rattlesnake (Crotalus scutulatus scutulatus) venom metalloproteinases reveal a structural basis for differences in hemorrhagic activities. J Biol Phys 2014;40:193-216.
  • 10. Natarajan N, Basheer A, Mookkappan S, Periyasamy S. Reversible lower limb deep vein thrombosis following haemotoxic snakebite-a case report. AMJ 2014;7:232-5.
There are 10 citations in total.

Details

Other ID JA62PR59EA
Journal Section Research Article
Authors

Radu Ciprian Tincu This is me

Zoie Ghiorghiu This is me

Dana Tomescu This is me

Radu Alexandru Macovei This is me

Publication Date July 1, 2017
Published in Issue Year 2017 Volume: 34 Issue: 4

Cite

APA Tincu, R. C., Ghiorghiu, Z., Tomescu, D., Macovei, R. A. (2017). The Compartment Syndrome Associated with Deep Vein Thrombosis due to Rattlesnake Bite: A Case Report. Balkan Medical Journal, 34(4), 367-370.
AMA Tincu RC, Ghiorghiu Z, Tomescu D, Macovei RA. The Compartment Syndrome Associated with Deep Vein Thrombosis due to Rattlesnake Bite: A Case Report. Balkan Medical Journal. July 2017;34(4):367-370.
Chicago Tincu, Radu Ciprian, Zoie Ghiorghiu, Dana Tomescu, and Radu Alexandru Macovei. “The Compartment Syndrome Associated With Deep Vein Thrombosis Due to Rattlesnake Bite: A Case Report”. Balkan Medical Journal 34, no. 4 (July 2017): 367-70.
EndNote Tincu RC, Ghiorghiu Z, Tomescu D, Macovei RA (July 1, 2017) The Compartment Syndrome Associated with Deep Vein Thrombosis due to Rattlesnake Bite: A Case Report. Balkan Medical Journal 34 4 367–370.
IEEE R. C. Tincu, Z. Ghiorghiu, D. Tomescu, and R. A. Macovei, “The Compartment Syndrome Associated with Deep Vein Thrombosis due to Rattlesnake Bite: A Case Report”, Balkan Medical Journal, vol. 34, no. 4, pp. 367–370, 2017.
ISNAD Tincu, Radu Ciprian et al. “The Compartment Syndrome Associated With Deep Vein Thrombosis Due to Rattlesnake Bite: A Case Report”. Balkan Medical Journal 34/4 (July 2017), 367-370.
JAMA Tincu RC, Ghiorghiu Z, Tomescu D, Macovei RA. The Compartment Syndrome Associated with Deep Vein Thrombosis due to Rattlesnake Bite: A Case Report. Balkan Medical Journal. 2017;34:367–370.
MLA Tincu, Radu Ciprian et al. “The Compartment Syndrome Associated With Deep Vein Thrombosis Due to Rattlesnake Bite: A Case Report”. Balkan Medical Journal, vol. 34, no. 4, 2017, pp. 367-70.
Vancouver Tincu RC, Ghiorghiu Z, Tomescu D, Macovei RA. The Compartment Syndrome Associated with Deep Vein Thrombosis due to Rattlesnake Bite: A Case Report. Balkan Medical Journal. 2017;34(4):367-70.