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Therapeutic Source: Plants

Year 2022, Volume: 5 Issue: 3, 336 - 343, 01.07.2022
https://doi.org/10.47115/bsagriculture.1078368

Abstract

Plants are used to cure many diseases due to their therapeutic properties. The history of phytotherapeutic applications using plants for treatment goes back thousands of years. The reason plants have been used for treatment for so long is that they have produced secondary compounds with thousands of different structures that have therapeutic properties. Many of the secondary metabolites produced by plants have been converted into drugs through rational phytotherapeutic applications. The demand for herbal medicines is increasing day by day all over the world because the synthetic drugs used for treatment have serious side effects, are not sufficiently effective and there are diseases for which there is no cure yet. In our country there are almost 13 thousand plant taxa, and very few of these plants are used for medicinal purposes. In fact, thousands of plants and tens of thousands of secondary compounds that can be used for treatment are waiting to be discovered. The discovery of new, effective and safe herbal medicines is a remarkable field of research today, and the discovery of effective and safe alternative medicines will bring great benefits to human health.

References

  • Afsheen N, Jahan N, Ijaz M, Manzoor A, Khan KM, Hina S. 2018. Cardioprotective and metabolomic profiling of selected medicinal plants against oxidative stress. Oxidat Medic Cell Longev, 2018: 9819360. DOI: 10.1155/2018/9819360.
  • Arslan N. 2016. Tibbi ve aromatik bitkiler. Türkiye Toh Bir Derg, 17(5): 66-69.
  • Avancini G, Abreu IN, Saldaña MD, Mohamed RS, Mazzafera P. 2003. Induction of pilocarpine formation in jaborandi leaves by salicylic acid and methyljasmonate. Phytochem, 63(2): 171-175.
  • Balunas MJ, Kinghorn AD. 2005. Drug discovery from medicinal plants. Life Sci, 78(5): 431-441.
  • Bailey CJ, Day C. 2004. Metformin: Its botanical background. Pract Diabetes, 21: 115-117.
  • Batiha GES, Alkazmi LM, Nadwa EH, Rashwan EK, Beshbishy AM, Shaheen H, Wasef L. 2020. Physostigmine: A plant alkaloid isolated from Physostigma venenosum: A review on pharmacokinetics, pharmacological and toxicological activities. J Drug Deliv Therapeutics, 10(1-s): 187-190.
  • Beppe GJ, Dongmo AB, Foyet HS, Tsabang N, Olteanu Z, Cioanca O, Hritcu L. 2014. Memory-enhancing activities of the aqueous extract of Albizia adianthifolia leaves in the 6-hydroxydopamine-lesion rodent model of Parkinson’s disease. BMC Comp Alter Medic, 14(1): 1-11.
  • Bohlmann J, Keeling CI. 2008. Terpenoid biomaterials. Plant J, 54(4): 656-669.
  • Bonfil RD, Russo DM, Binda MM, Delgado FM, Vincenti M. 2002. Higher antitumor activity of vinflunine than vinorelbine against an orthotopic murine model of transitional cell carcinoma of the bladder. Urol Oncol, 7(4): 159-166.
  • Cars O, Nordberg P. 2005. Antibiotic resistance–The faceless threat. Int J Risk Safety Medic, 17(3,4): 103-110.
  • Colalto C. 2018. What phytotherapy needs: Evidence‐based guidelines for better clinical practice. Phytother Res, 32(3): 413-425.
  • Coruh N, Ozdogan N. 2014. Fluorescent coumarin components of the bark of Aesculus hippocastanum. J Liquid Chromat Related Technol, 37(10): 1334-1350.
  • Cox PA, Balick MJ. 1994. The ethnobotanical approach to drug discovery. Sci American, 270(6): 82-87.
  • Cragg GM, Newman DJ. 2005. Plants as a source of anti-cancer agents. J Ethnopharm, 100(1-2): 72-79.
  • Crozier A, Clifford MN, Ashihara H. 2008. Plant secondary metabolites: occurrence, structure and role in the human diet. Blackwell Publishing, New York, US, pp: 384.
  • Dar RA, Shahnawaz M, Qazi PH. 2017. General overview of medicinal plants: A review. J Phytopharmacol, 6(6): 349-351.
  • Frantz S, Smith A. 2003. New drug approvals for 2002. Nature Rev Drug Discovery, 2(2): 95-96.
  • Fürst R, Zündorf I. 2015. Evidence-based phytotherapy in Europe: where do we stand. Planta Med, 81(12-13): 962-967.
  • Ghosh S, Subudhi E, Nayak S. 2008. Antimicrobial assay of Stevia rebaudiana Bertoni leaf extracts against 10 pathogens. Int J Integ Biol, 2(1): 27-31.
  • Gnonlonfin GB, Sanni A, Brimer L. 2012. Review scopoletin–a coumarin phytoalexin with medicinal properties. Critical Rev Plant Sci, 31(1): 47-56.
  • Governa P, Baini G, Borgonetti V, Cettolin G, Giachetti D, Magnano AR, Biagi M. 2018. Phytotherapy in the management of diabetes: a review. Molecules, 23(1): 105.
  • Gurib-Fakim A. 2006. Medicinal plants: traditions of yesterday and drugs of tomorrow. Molec Aspects Medic, 27(1): 1-93.
  • Hall MG, Wilks MF, Provan WM, Eksborg S, Lumholtz B. 2001. Pharmacokinetics and harmacodynamics of NTBC (2-(2-nitro-4-fluoromethylbenzoyl) - 1,3-cyclohexanedione) and mesotrione, inhibitors of 4-hydroxyphenyl pyruvate dioxygenase (HPPD) following a single dose to healthy male volunteers. British J Clin Pharmacol, 52(2), 169-177.
  • Hamburger M, Hostettmann K. 1991. Bioactivity in plants: the link between phytochemistry and medicine. Phytochem, 30: 3864-3874.
  • Heinrich M. 2001. Ethnobotanik und Ethnopharmazie. Eine Einführung, Stuttgart, Germany, pp: 159.
  • Heinrich M, Teoh HL. 2004. Galanthamine from snowdrop—the development of a modern drug against Alzheimer’s disease from local Caucasian knowledge. J Ethnopharmacol, 92(2-3): 147-162.
  • Heinrich M. 2010. 3.12—Ethnopharmacology and drug discovery. Comprehensive Natural Products II. Elsevier, Oxford, UK, pp: 351.
  • Heinrich M, Williamson EM, Gibbons S, Barnes J, Prieto-Garcia J. 2017. Fundamentals of Pharmacognosy and Phytotherapy E-Book: Elsevier Health Sciences, New York, US, pp: 360.
  • Hesse M. 2002. Alkaloids: nature's curse or blessing?. John Wiley & Sons, New York, US, pp: 413.
  • Hroboňová K, Machyňáková A, Čižmárik J. 2018. Determination of dicoumarol in Melilotus officinalis L. by using molecularly imprinted polymer solid-phase extraction coupled with high performance liquid chromatography. J Chromatography A, 1539: 93-102.
  • Jachak SM, Saklani A. 2007. Challenges and opportunities in drug discovery from plants. Curr Sci, 92(9): 1251-1257.
  • Kamble SS, Gacche RN. 2019. Evaluation of anti-breast cancer, anti-angiogenic and antioxidant properties of selected medicinal plants. European J Integ Medic, 25: 13-19.
  • Katiyar C, Gupta A, Kanjilal S, Katiyar S. 2012. Drug discovery from plant sources: An integrated approach. Ayu, 33(1): 10.
  • Klein JD, Wilson KM, Sesselberg TS, Gray NJ, Yussman S, West J. 2005. Adolescents’ knowledge of and beliefs about herbs and dietary supplements: a qualitative study. J Adolescent Health, 37(5): 401-409.
  • Kumar S, Paul S, Walia YK, Kumar A, Singhal P. 2015. Therapeutic potential of medicinal plants: a review. J Biol Chem Chron, 1(1): 46-54.
  • Loomis WD, Croteau R. 1980. Biochemistry of terpenoids. In Lipids: structure and function. Elsevier, New York, US, pp: 418.
  • Maclagan T. 1876. Drug discovery: A history. Lancet, 107: 342.
  • Mazimba O. 2017. Umbelliferone: Sources, chemistry and bioactivities review. Bull Faculty of Pharm Cairo Univ, 55(2): 223-232.
  • McCord JM. 2000. The evolution of free radicals and oxidative stress. American J Medic, 108(8): 652-659.
  • Mitchell G, Bartlett DW, Fraser TEM, Hawkes TR, Holt DC, Townson JK, Wichert RA. 2001. Mesotrione: a new selective herbicide for use in maize. Pest Manag Sci F ormerPesticide Sci, 57(2): 120-128.
  • Mundy C, Kirkpatrick P. 2004. Tiotropium bromide. Nature Rev Drug Discov, 3(8): 643.
  • Nazir R, Kumar V, Gupta S, Dwivedi P, Pandey DK, Dey A. 2021. Biotechnological strategies for the sustainable production of diosgenin from Dioscorea spp. Applied Microbiol Biotechnol, 105(2): 569-585.
  • Nicholson RL, Hammerschmidt R. 1992. Phenolic compounds and their role in disease resistance. Annual Rev Phytopathol, 30(1): 369-389.
  • Özçelik G, Toprak D. 2015. Bitkisel tedavi neden tercih ediliyor? Ankara Medic J, 15(2): 48-58.
  • Patwardhan B, Vaidya AD, Chorghade M. 2004. Ayurveda and natural products drug discovery. Curr Sci, 86(6): 789-799.
  • Permin H, Norn S, Kruse E, Kruse PR. 2016. On the history of Cinchona bark in the treatment of Malaria. Dansk Medicinhistorisk Årbog, 44: 9-30.
  • Rana S, Dixit S, Mittal A. 2017. Anticancer effects of chemotherapy and nature products. J Medic Discov, 2(2): 1-8.
  • Raskin I, Ribnicky D, Komarnytsky S, Ilic N, Poulev A, Borisjuk N, Brinker A, Moreno A, Ripoll C, Yakoby N, Cornwell T, Pastor I, Fridlender B. 2002. Plants and human health in the twenty-first century. Trends Biotechnol, 20(12): 522-531.
  • Reichling J. 2018. Plant–microbe interactions and secondary metabolites with antibacterial, antifungal and antiviral properties. Ann Plant Rev Online, 4: 214-347.
  • Rumack BH. 1973. Anticholinergic poisoning: treatment with physostigmine. Pediatrics, 52(3): 449-451.
  • Samuelsson G. 2004. Drugs of Natural origin: a textbook of pharmacognosy, 5th edd. Swedish Pharmaceutical Press, Stockholm, Sweden, pp: 620.
  • Sappington J. 1844. The theory and treatment of fevers. Forgotten Books, St Louis, MO, US, pp: 222.
  • Sarker SD, Nahar L. 2018. Evidence-based phytotherapy: what, why and how? Trends Phytochem Res, 2(3): 125-126.
  • Schulz RH, Tyler V. 1998. Rational phytotherapy: a physician’s guide to herbal medicine. Springer, Berlin, Germany, pp: 383.
  • Siddiqui AA, Iram F, Siddiqui S, Sahu K. 2014. Role of natural products in drug discovery process. Int J Drug Dev Res, 6(2): 172-204.
  • Soto-Vaca A, Gutierrez A, Losso JN, Xu Z, Finley JW. 2012. Evolution of phenolic compounds from color and flavor problems to health benefits. J Agri Food Chem, 60(27): 6658-6677.
  • Süntar I. 2020. Importance of ethnopharmacological studies in drug discovery: role of medicinal plants. Phytochem Rev, 19(5): 1199-1209.
  • Travaini ML, Sosa GM, Ceccarelli EA, Walter H, Cantrell CL, Carrillo NJ, Duke SO. 2016. Khellin and visnagin, furanochromones from Ammi visnaga (L.) Lam., as potential bioherbicides. J Agri Food Chem, 64(50): 9475-9487.
  • van Agtmael MA, Eggelte TA, van Boxtel CJ. 1999. Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication. Trends Pharmacol Sci, 20(5): 199- 205.
  • Verpoorte R. 1998. Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development. Drug Discov Today, 3(5): 232-238.
  • Withering W. 2009. An account of the foxglove and some of its medicinal uses. J and J Robinson, London, UK, pp: 1785.
  • Yao LH, Jiang YM, Shi J, Tomas-Barberan F, Datta N, Singanusong R, Chen S. 2004. Flavonoids in food and their health benefits. Plant Foods Human Nutri, 59(3): 113-122.
  • Yu D, Suzuki M, Xie L, Morris-Natschke SL, Lee KH. 2003. Recent progress in the development of coumarin derivatives as potent anti-HIV agents. Medic Res Rev, 23(3): 322-345.
  • Zhang L, Song J, Kong L, Yuan T, Li W, Zhang W, Du G. 2020. The strategies and techniques of drug discovery from natural products. Pharmacol Therapeut, 216: 107686.
Year 2022, Volume: 5 Issue: 3, 336 - 343, 01.07.2022
https://doi.org/10.47115/bsagriculture.1078368

Abstract

References

  • Afsheen N, Jahan N, Ijaz M, Manzoor A, Khan KM, Hina S. 2018. Cardioprotective and metabolomic profiling of selected medicinal plants against oxidative stress. Oxidat Medic Cell Longev, 2018: 9819360. DOI: 10.1155/2018/9819360.
  • Arslan N. 2016. Tibbi ve aromatik bitkiler. Türkiye Toh Bir Derg, 17(5): 66-69.
  • Avancini G, Abreu IN, Saldaña MD, Mohamed RS, Mazzafera P. 2003. Induction of pilocarpine formation in jaborandi leaves by salicylic acid and methyljasmonate. Phytochem, 63(2): 171-175.
  • Balunas MJ, Kinghorn AD. 2005. Drug discovery from medicinal plants. Life Sci, 78(5): 431-441.
  • Bailey CJ, Day C. 2004. Metformin: Its botanical background. Pract Diabetes, 21: 115-117.
  • Batiha GES, Alkazmi LM, Nadwa EH, Rashwan EK, Beshbishy AM, Shaheen H, Wasef L. 2020. Physostigmine: A plant alkaloid isolated from Physostigma venenosum: A review on pharmacokinetics, pharmacological and toxicological activities. J Drug Deliv Therapeutics, 10(1-s): 187-190.
  • Beppe GJ, Dongmo AB, Foyet HS, Tsabang N, Olteanu Z, Cioanca O, Hritcu L. 2014. Memory-enhancing activities of the aqueous extract of Albizia adianthifolia leaves in the 6-hydroxydopamine-lesion rodent model of Parkinson’s disease. BMC Comp Alter Medic, 14(1): 1-11.
  • Bohlmann J, Keeling CI. 2008. Terpenoid biomaterials. Plant J, 54(4): 656-669.
  • Bonfil RD, Russo DM, Binda MM, Delgado FM, Vincenti M. 2002. Higher antitumor activity of vinflunine than vinorelbine against an orthotopic murine model of transitional cell carcinoma of the bladder. Urol Oncol, 7(4): 159-166.
  • Cars O, Nordberg P. 2005. Antibiotic resistance–The faceless threat. Int J Risk Safety Medic, 17(3,4): 103-110.
  • Colalto C. 2018. What phytotherapy needs: Evidence‐based guidelines for better clinical practice. Phytother Res, 32(3): 413-425.
  • Coruh N, Ozdogan N. 2014. Fluorescent coumarin components of the bark of Aesculus hippocastanum. J Liquid Chromat Related Technol, 37(10): 1334-1350.
  • Cox PA, Balick MJ. 1994. The ethnobotanical approach to drug discovery. Sci American, 270(6): 82-87.
  • Cragg GM, Newman DJ. 2005. Plants as a source of anti-cancer agents. J Ethnopharm, 100(1-2): 72-79.
  • Crozier A, Clifford MN, Ashihara H. 2008. Plant secondary metabolites: occurrence, structure and role in the human diet. Blackwell Publishing, New York, US, pp: 384.
  • Dar RA, Shahnawaz M, Qazi PH. 2017. General overview of medicinal plants: A review. J Phytopharmacol, 6(6): 349-351.
  • Frantz S, Smith A. 2003. New drug approvals for 2002. Nature Rev Drug Discovery, 2(2): 95-96.
  • Fürst R, Zündorf I. 2015. Evidence-based phytotherapy in Europe: where do we stand. Planta Med, 81(12-13): 962-967.
  • Ghosh S, Subudhi E, Nayak S. 2008. Antimicrobial assay of Stevia rebaudiana Bertoni leaf extracts against 10 pathogens. Int J Integ Biol, 2(1): 27-31.
  • Gnonlonfin GB, Sanni A, Brimer L. 2012. Review scopoletin–a coumarin phytoalexin with medicinal properties. Critical Rev Plant Sci, 31(1): 47-56.
  • Governa P, Baini G, Borgonetti V, Cettolin G, Giachetti D, Magnano AR, Biagi M. 2018. Phytotherapy in the management of diabetes: a review. Molecules, 23(1): 105.
  • Gurib-Fakim A. 2006. Medicinal plants: traditions of yesterday and drugs of tomorrow. Molec Aspects Medic, 27(1): 1-93.
  • Hall MG, Wilks MF, Provan WM, Eksborg S, Lumholtz B. 2001. Pharmacokinetics and harmacodynamics of NTBC (2-(2-nitro-4-fluoromethylbenzoyl) - 1,3-cyclohexanedione) and mesotrione, inhibitors of 4-hydroxyphenyl pyruvate dioxygenase (HPPD) following a single dose to healthy male volunteers. British J Clin Pharmacol, 52(2), 169-177.
  • Hamburger M, Hostettmann K. 1991. Bioactivity in plants: the link between phytochemistry and medicine. Phytochem, 30: 3864-3874.
  • Heinrich M. 2001. Ethnobotanik und Ethnopharmazie. Eine Einführung, Stuttgart, Germany, pp: 159.
  • Heinrich M, Teoh HL. 2004. Galanthamine from snowdrop—the development of a modern drug against Alzheimer’s disease from local Caucasian knowledge. J Ethnopharmacol, 92(2-3): 147-162.
  • Heinrich M. 2010. 3.12—Ethnopharmacology and drug discovery. Comprehensive Natural Products II. Elsevier, Oxford, UK, pp: 351.
  • Heinrich M, Williamson EM, Gibbons S, Barnes J, Prieto-Garcia J. 2017. Fundamentals of Pharmacognosy and Phytotherapy E-Book: Elsevier Health Sciences, New York, US, pp: 360.
  • Hesse M. 2002. Alkaloids: nature's curse or blessing?. John Wiley & Sons, New York, US, pp: 413.
  • Hroboňová K, Machyňáková A, Čižmárik J. 2018. Determination of dicoumarol in Melilotus officinalis L. by using molecularly imprinted polymer solid-phase extraction coupled with high performance liquid chromatography. J Chromatography A, 1539: 93-102.
  • Jachak SM, Saklani A. 2007. Challenges and opportunities in drug discovery from plants. Curr Sci, 92(9): 1251-1257.
  • Kamble SS, Gacche RN. 2019. Evaluation of anti-breast cancer, anti-angiogenic and antioxidant properties of selected medicinal plants. European J Integ Medic, 25: 13-19.
  • Katiyar C, Gupta A, Kanjilal S, Katiyar S. 2012. Drug discovery from plant sources: An integrated approach. Ayu, 33(1): 10.
  • Klein JD, Wilson KM, Sesselberg TS, Gray NJ, Yussman S, West J. 2005. Adolescents’ knowledge of and beliefs about herbs and dietary supplements: a qualitative study. J Adolescent Health, 37(5): 401-409.
  • Kumar S, Paul S, Walia YK, Kumar A, Singhal P. 2015. Therapeutic potential of medicinal plants: a review. J Biol Chem Chron, 1(1): 46-54.
  • Loomis WD, Croteau R. 1980. Biochemistry of terpenoids. In Lipids: structure and function. Elsevier, New York, US, pp: 418.
  • Maclagan T. 1876. Drug discovery: A history. Lancet, 107: 342.
  • Mazimba O. 2017. Umbelliferone: Sources, chemistry and bioactivities review. Bull Faculty of Pharm Cairo Univ, 55(2): 223-232.
  • McCord JM. 2000. The evolution of free radicals and oxidative stress. American J Medic, 108(8): 652-659.
  • Mitchell G, Bartlett DW, Fraser TEM, Hawkes TR, Holt DC, Townson JK, Wichert RA. 2001. Mesotrione: a new selective herbicide for use in maize. Pest Manag Sci F ormerPesticide Sci, 57(2): 120-128.
  • Mundy C, Kirkpatrick P. 2004. Tiotropium bromide. Nature Rev Drug Discov, 3(8): 643.
  • Nazir R, Kumar V, Gupta S, Dwivedi P, Pandey DK, Dey A. 2021. Biotechnological strategies for the sustainable production of diosgenin from Dioscorea spp. Applied Microbiol Biotechnol, 105(2): 569-585.
  • Nicholson RL, Hammerschmidt R. 1992. Phenolic compounds and their role in disease resistance. Annual Rev Phytopathol, 30(1): 369-389.
  • Özçelik G, Toprak D. 2015. Bitkisel tedavi neden tercih ediliyor? Ankara Medic J, 15(2): 48-58.
  • Patwardhan B, Vaidya AD, Chorghade M. 2004. Ayurveda and natural products drug discovery. Curr Sci, 86(6): 789-799.
  • Permin H, Norn S, Kruse E, Kruse PR. 2016. On the history of Cinchona bark in the treatment of Malaria. Dansk Medicinhistorisk Årbog, 44: 9-30.
  • Rana S, Dixit S, Mittal A. 2017. Anticancer effects of chemotherapy and nature products. J Medic Discov, 2(2): 1-8.
  • Raskin I, Ribnicky D, Komarnytsky S, Ilic N, Poulev A, Borisjuk N, Brinker A, Moreno A, Ripoll C, Yakoby N, Cornwell T, Pastor I, Fridlender B. 2002. Plants and human health in the twenty-first century. Trends Biotechnol, 20(12): 522-531.
  • Reichling J. 2018. Plant–microbe interactions and secondary metabolites with antibacterial, antifungal and antiviral properties. Ann Plant Rev Online, 4: 214-347.
  • Rumack BH. 1973. Anticholinergic poisoning: treatment with physostigmine. Pediatrics, 52(3): 449-451.
  • Samuelsson G. 2004. Drugs of Natural origin: a textbook of pharmacognosy, 5th edd. Swedish Pharmaceutical Press, Stockholm, Sweden, pp: 620.
  • Sappington J. 1844. The theory and treatment of fevers. Forgotten Books, St Louis, MO, US, pp: 222.
  • Sarker SD, Nahar L. 2018. Evidence-based phytotherapy: what, why and how? Trends Phytochem Res, 2(3): 125-126.
  • Schulz RH, Tyler V. 1998. Rational phytotherapy: a physician’s guide to herbal medicine. Springer, Berlin, Germany, pp: 383.
  • Siddiqui AA, Iram F, Siddiqui S, Sahu K. 2014. Role of natural products in drug discovery process. Int J Drug Dev Res, 6(2): 172-204.
  • Soto-Vaca A, Gutierrez A, Losso JN, Xu Z, Finley JW. 2012. Evolution of phenolic compounds from color and flavor problems to health benefits. J Agri Food Chem, 60(27): 6658-6677.
  • Süntar I. 2020. Importance of ethnopharmacological studies in drug discovery: role of medicinal plants. Phytochem Rev, 19(5): 1199-1209.
  • Travaini ML, Sosa GM, Ceccarelli EA, Walter H, Cantrell CL, Carrillo NJ, Duke SO. 2016. Khellin and visnagin, furanochromones from Ammi visnaga (L.) Lam., as potential bioherbicides. J Agri Food Chem, 64(50): 9475-9487.
  • van Agtmael MA, Eggelte TA, van Boxtel CJ. 1999. Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication. Trends Pharmacol Sci, 20(5): 199- 205.
  • Verpoorte R. 1998. Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development. Drug Discov Today, 3(5): 232-238.
  • Withering W. 2009. An account of the foxglove and some of its medicinal uses. J and J Robinson, London, UK, pp: 1785.
  • Yao LH, Jiang YM, Shi J, Tomas-Barberan F, Datta N, Singanusong R, Chen S. 2004. Flavonoids in food and their health benefits. Plant Foods Human Nutri, 59(3): 113-122.
  • Yu D, Suzuki M, Xie L, Morris-Natschke SL, Lee KH. 2003. Recent progress in the development of coumarin derivatives as potent anti-HIV agents. Medic Res Rev, 23(3): 322-345.
  • Zhang L, Song J, Kong L, Yuan T, Li W, Zhang W, Du G. 2020. The strategies and techniques of drug discovery from natural products. Pharmacol Therapeut, 216: 107686.
There are 64 citations in total.

Details

Primary Language English
Subjects Structural Biology
Journal Section Reviews
Authors

Hilal Ateş 0000-0002-5460-2360

Erkan Yalçın 0000-0001-5571-7613

Publication Date July 1, 2022
Submission Date February 24, 2022
Acceptance Date April 20, 2022
Published in Issue Year 2022 Volume: 5 Issue: 3

Cite

APA Ateş, H., & Yalçın, E. (2022). Therapeutic Source: Plants. Black Sea Journal of Agriculture, 5(3), 336-343. https://doi.org/10.47115/bsagriculture.1078368

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