Evaluation of Gossypium herbaceum Leaf Powder's Nutritional Composition and Nutraceutical Properties

Year 2024, Volume: 7 Issue: 1, 7 - 13, 01.01.2024

Olugbenga David Oloruntola , Simeon Olugbenga Ayodele , Victor Akinduro , Olatunji Abubakar Jimoh , Andrew Falowo , Clement Oluwafemi Osowe , Fehintoluwa Stellamaris Oladebeye

https://doi.org/10.47115/bsagriculture.1320303

Cited By: 1

Abstract

The objective of this study is to identify the proximate composition, phytochemical profile, and anti-diabetic, anti-inflammatory and antioxidant properties of Gossypium herbaceum leaf powder (GLP). The fresh leaves of the G. herbaceum were collected, cleansed with fresh water, drained and allowed to dry in the shade, ground to GLP and analysed. The crude fibre (42.93%) and nitrogen-free extract (36.46 %) have a relatively high proportion in GLP; while ash (2.47%) has the lowest proportion. The GLP has relatively high phenol (219.20 mg/g) when compared to flavonoids (81.03 mg/g), tannins (69.56 mg/g), saponins (66.67 mg/g) and alkaloids (55.80 mg/g). The α-amylase inhibition and α-glucosidase inhibition of GLP were 48.45% and 30.68%, respectively. The percentage of albumin denaturation inhibition and anti-proteinase activity of GLP was 22.88% and 43.87%, respectively. The lipid peroxidation inhibition, vitamin C, Fe chelation and 2,2-diphenyl-1-picrylhydrazyl were 35.43%, 23.87%, 11.76% and 88.16%, respectively. GLP exhibits anti-inflammatory, anti-diabetic and antioxidant properties.

Keywords

Gossypium herbaceum, Phytogenic supplement, Anti-oxidant, Anti-diabetic, Anti-inflammatory

References

• Adejoro FA, Hassen A, Akanmu AM, Morgavi DP. 2020. Replacing urea with nitrate as a non-protein nitrogen source increases lambs’ growth and reduces methane production, whereas acacia tannin has no effect. Anim Feed Sci Technol, 259: 114360. https://doi.org/10.1016/j.anifeedsci.2019.114360.
• Alam S, Sarker MMR, Sultana TN, Chowdhury MNR, Rashid MA, Chaity NI, Zhao C, Xiao J, Hafez EE, Khan SA, Mohamed IN. 2022. Antidiabetic phytochemicals from medicinal plants: Prospective candidates for new drug discovery and development. Front Endocrinol, 13: 800714. https://doi.org/10.3389/fendo.2022.80071.
• AOAC. 2010. Official methods of analysis of association of official analytical chemists. 18th Edition, Washington DC, US, pp: 771.
• Atpadkar PP, Gopavaram S, Chaudhary S. 2023. Natural-product-inspired bioactive alkaloids agglomerated with potential antioxidant activity: Recent advancements on structure-activity relationship studies and future perspectives. Vitamins Hormones, 121: 355-393. https://doi.org/10.1016/bs.vh.2022.10.002.
• Bach Knudsen KE, Lærke HN, Jørgensen H. 2013. Carbohydrates and carbohydrate utilization in swine. In: Chiba LI, editor. Sustainable swine nutrition. Wiley, Ames, US, pp: 109-137. https://doi.org/10.1002/9781118491454.ch5.
• Bahadoran Z, Mirmiran P, Azizi F. 2013. Dietary polyphenols as potential nutraceuticals in management of diabetes: a review. J Diabetes Metab Disord, 12: 1. https://doi.org/10.1186/2251-6581-12-43.
• Bajpai VK, Park Y, Agrawal P. 2015. Studies on phytochemical analysis, antioxidant and lipid peroxidation inhibitory effects of a medicinal plants, Coleus forskohlii. Front Life Sci, 8(2): 139-147.
• Benderitter M, Maupoli V, Vergely C, Dalloz F, Briot F, Rochette L. 1998. Studies by electron paramagnetic resonance of the importance of iron in the hydroxyl scavenging properties of ascorbic acid in plasma: Effects of iron chelators. Fundam Clin Pharmacol, 12(5): 510-516.
• Burri SCM, Ekholm A, Bleive U, Püssa T, Jensen M, Hellström J, Mäkinen S, Korpinen R, Mattila PH, Radenkovs V, Segliņa D, Håkansson A, Rumpunen K, Tornberg E. 2020. Lipid oxidation inhibition capacity of plant extracts and powders in a processed meat model system. Meat Sci, 162; 108033. https://doi.org/10.1016/j.meatsci.2019.108033.
• Chau CF, Huang YL. 2003. Comparison of the chemical composition and physicochemical properties of different fibres prepared from peel of the Citrus sinensis L. Cv. Liucheng. J Agric Food Chem, 51: 2615-2618.
• Chung KT, Wong TY, Wei CI, Huang YW, Lin Y. 1998. Tannins and human health: a review. Crit Rev Food Sci Nutr, 38(6): 421-464. https://doi.org/10.1080/10408699891274273.
• Dej-adisai S, Pitakbut T. 2015. Determination of α-glucosidase inhibitory activity from selected Fabaceae plants. Pakistan J Pharmacol Sci, 28(5): 1679-1683.
• Dharmadeva S, Galgamuwa LS, Prasadinie C, Kumarasinghe N. 2018. In vitro anti-inflammatory activity of Ficus racemosa L. bark using albumin denaturation method. Ayu, 39(4): 239-242. https://doi.org/10.4103/ayu.AYU_27_18.
• Dhingra D, Michael M, Rajput H, Patil RT. 2012. Dietary fibre in foods: a review. Journal Food Sci Techn, 49(3): 255-266. https://doi.org/10.1007/s13197-011-0365-5.
• Ebrahimzadeh MA, Pourmorad F, Bekhradnia AR. 2008. Iron chelating activity, phenol and flavonoid content of some medicinal plants from Iran. African J Biotech, 7(18): 3188-3192.
• Falowo AB, Oloruntola OD, Akinmoladun OF. 2023. Assessment of nutritional composition and antioxidant properties of Dysphania ambrosioides (L.) mosyakin & clemants and Crassocephalum crepidioides Leaf meal as potential feed additives. Turkish J Agri Food Sci Technol, 11(2): 274-279. https://doi.org/10.24925/turjaf.v11i2.274-279.5603.
• Ganguly S. 2013. Herbal and plant derived natural products as growth promoting nutritional supplements for poultry birds: a review. J Pharm Sci Innov, 2: 12-13. https://doi.org/10.7897/2277-4572.02323.
• Heredia A, Jimenez A, Fernandez-Bolanos J, Guillen R, Rodriguez R. 2002. Fibra Alimentaria. Biblioteca de Ciencias, Madrid, Spain, pp: 117.
• Kumar N, Goel N. 2019. Phenolic acids: Natural versatile molecules with promising therapeutic applications. Biotechnol Reports, 24: e00370. https://doi.org/10.1016/j.btre.2019.e00370.
• Larayetan RA, Ayeni G, Yahaya A, Ajayi A, Omale S, Ishaq U, Abiodun DJ, Olisah C, Aigbogun J, Enyioma-Alozie S. 2021. Chemical composition of Gossypium herbaceum linn and its antioxidant, antibacterial, cytotoxic and antimalarial activities. Clin Complem Medic Pharmacol, 6(1): 2021. 100008, https://doi.org/10.1016/j.ccmp.2021.100008.
• Maroon JC, Bost JW, Maroon A. 2010. Natural anti-inflammatory agents for pain relief. Surg Neurol Int, 1: 80.
• Muhammad Z, Masanawa AA, Pyeng AK. 2014. Phytochemical and mineral analysis of methanolic extract of Gossypium barbadense L. (cotton leaves). Annals Exp Biol, 2(4): 11-15.
• Nicoletti M. 2012. Nutraceuticals and botanicals: overview and perspectives. Int J Food Sci Nutr, 63(1): 2-6. https://doi.org/10.3109/09637486.2011.628012.
• Oloruntola OD, Ayodele SO, Adeyeye SA, Fasuhami OS, Osowe CO, Ganiyu TO. 2022. Proximate composition, phytochemical profile, antioxidant, antidiabetic and anti-inflammatory properties of Justicia carnea leaf powder. BSJ Agri, 5(4): 415-423. https://doi.org/10.47115/bsagriculture.114526.
• Oloruntola OD, Ayodele SO. 2022. Phytochemical, proximate and mineral composition, antioxidant and antidiabetic properties evaluation and comparison of mistletoe leaves from moringa and kolanut trees. Turkish J Agri Food Sci Technol, 10(8): 1524-1531. https://doi.org/10.24925/turjaf.v10i8.1524-1531.5134.
• Oloruntola OD. 2021. Proximate, phytochemical, mineral composition and antioxidant activity of Anacardium occidentale L. leaf powder. Dysona Life Sci, 2(2021): 39-49. https://doi.org/10.30493/DLS.2021.290718.
• Oloruntola OD. 2022. Juglans regia kernel meal; A prospective nutraceutical feed supplement. Biotech Stud, 31(2): 87-94. http://doi.org/10.38042/biotechstudies.1222785.
• Osman NI, Sidik NJ, Awal A, Adam NA. 2016. Rezali NI. In vitro xanthine oxidase and albumin denaturation inhibition assay of Barringtonia racemosa L. and total phenolic content analysis for potential anti-inflammatory use in gouty arthritis. J Intercult Ethnopharmacol, 5(4): 343-349. https://doi.org/10.5455/jice.20160731025522.
• Osowe CO, Olowu OPA, Adu OA, Oloruntola OD, Chineke CA. 2021. Proximate and mineral composition, phytochemical analysis, and antioxidant activity of fig trees (Ficus spp.) leaf powder. Asian J Biochem Gen Molec Bio, 9(1): 19-29.
• Otles S, Yalcin B. 2012. Phenolic compounds analysis of root, stalk, and leaves of Nettle. Sci World J, 2012: 564367. https://doi.org/10.1100/2012/564367.
• Ozata M, Mergen M, Oktenli C, Aydin A, Sanisoglu SY, Bolu E, Yilmaz MI, Sayal A, Isimer A, Ozdemir IC. 2002. Increased oxidative stress and hypozincemia in male obesity. Clin Biochem, 35(8): 627-631. https://doi.org/10.1016/s0009-9120(02)00363-6.
• Panche AN, Diwan AD, Chandra SR. 2016. Flavonoids: an overview. J Nutrit Sci, 5: e47. https://doi.org/10.1017/jns.2016.41.
• Poovitha S, Parani M. 2016. In vitro and in vivo α-amylase and α-glucosidase inhibiting activities of the protein extracts from two varieties of bitter gourd (Momordica charantia L.). BMC Complement Altern Med, 16(Suppl 1): 185. https://doi.org/10.1186/s12906-016-1085-1.
• Rajesh A, Dossa A, Tresina PS, Mohan VR. 2019. Anti-inflammatory activity of methanol extract of Niebuhria apetala (Roth) Dunn – in vitro models. Asian J Pharmaceut Clin Res, 12(5): 278-281.
• Sharma K, Kaur R, Kumar S, Saini RK, Sharma S, Pawde SV, Kumar V. 2023. Saponins: A concise review on food related aspects, applications and health implications, Food Chem Advan, 2: 100191. https://doi.org/10.1016/j.focha.2023.100191.
• Shi J, Arunasalam K, Yeung D. Kakuda Y, Mittal G, Jiang Y. 2004. Saponins from edible legumes: chemistry, processing, and health benefits. J Med Food, 7(1): 67-78. https://doi.org/10.1089/109662004322984734.
• Sudan R, Bhagat M. Gupta S, Singh J, Koul A. 2014. Iron (FeII) chelation, ferric reducing antioxidant power, and immune modulating potential of Arisaema jacquemontii (Himalayan Cobra Lily). BioMed Res Int, 2014: 1-7. https://doi.org/10.1155/2014/179865.
• Traber MG, Stevens JF. 2011. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radical Biol Med, 51(5): 1000-1013. https://doi.org/10.1016/j.freeradbiomed.2011.05.017.
• Valenzuela-Grijalva NV, Pinelli-Saavedra A, Muhlia-Almazan A, Domínguez-Díaz D, González-Ríos H. 2017. Dietary inclusion effects of phytochemicals as growth promoters in animal production. J Anim Sci Technol, 59: 8. https://doi.org/10.1186/s40781-017-0133-9.
• Wickramaratne MN, Punchihewa J C, Wickramaratne DB. 2016. In-vitro alpha amylase inhibitory activity of the leaf extracts of Adenanthera pavonina. BMC Compl Alt Med, 16(1): 466. https://doi.org/10.1186/s12906-016-1452-y.
• Zhang H, Wang J, Liu Y, Sun B. 2015a. Peptides derived from oats improve insulin sensitivity and lower blood glucose in streptozotocin-induced diabetic mice. J Biomed Sci, 4: 1-7.
• Zhang, YJ, Gan RY, Li S, Zhou Y, Li AN, Xu DP, Li HB. 2015b. Antioxidant phytochemicals for the prev treat chronic dis. Molecules, 20(12): 21138-21156. https://doi.org/10.3390/molecules201219753.