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DAYANIKLILIK ANTRENMANI YAPAN ATLETLERDE E VİTAMİNİ KULLANIMININ OKSİDAN VE ANTİOKSİDAN KAPASİTESİ VE KAS HASARI ÜZERİNE ETKİSİ

Year 2012, Volume: 6 Issue: 3, 251 - 257, 01.12.2012

Abstract

Bu çalışma, atletlerde E vitamini kullanımının kas hasarı, oksidan ve antioksidan kapasite üzerine etkisinin araştırılması amacıyla yapılmıştır. Çalışmaya Erciyes Üniversitesi Beden Eğitimi ve Spor Yüksekokulunda okuyan aktif olarak spor yapan, benzer fiziksel özelliklere sahip, yaşları 20,75±1,84 olan n=16 deney grubu ve yaşları 20,42±1,78 olan n=12 kontrol grubu olmak üzere 28 kişi katıldı. Çalışmada her iki gruba da aynı egzersizler haftada 3 gün olmak üzere 30 gün süreyle uygulandı. Deney grubundaki atletlere 30 gün boyunca her gün 400 IU 268mg E vitamini verildi. Kontrol grubundaki atletlere herhangi bir şey verilmedi. Bir aylık antrenman öncesi ve sonrası atletlerin vücut ağırlığı ve vücut yağ yüzdesi değerleri ölçüldü. Biyokimyasal analizler ile total antioksidan kapasite, malondialdehit, kreatin kinaz ve laktat dehidrojenaz parametrelerine bakıldı. Deney ve kontrol gruplarının gruplar arası karşılaştırmaları sonucunda egzersiz öncesi CK ve LDH değerlerinde, egzersiz öncesi ve sonrası TAC ve MDA değerlerinde anlamlı farklılık bulunamazken p>0,05 , egzersiz sonrası CK ve LDH değerlerinde anlamlı farklılık meydana geldi p≤0.05 Grup içi karşılaştırmada ise, hem deney grubunun hem de kontrol grubunun egzersiz sonrası MDA değerinde anlamlı derecede artış saptanmıştır. Bu sonuç, egzersize bağlı olarak artan oksidatif strese karşı, E vitamini kullanımına rağmen antioksidan kapasitenin yetersiz kaldığını düşündürmektedir. Antioksidan savunma sistemindeki bu yetersizliğin nedeni olarak günlük alınan E vitamini miktarı düşünülmektedir.

References

  • Bader N., Bosy-Westphal A., Koch A., Rimbach G., Weimann A., Poulsen H.E., and Müller M.J., Effect of hyperbaric oxygen and vitamin C and E supplementation on biomarkers of oxidative stress in healthy men. The British Journal of Nutrition 98.pp.826-33, 2007.
  • Trombold J.R., Dhindsa M., Lin H.F., and Tanaka H., Arterial stiffening following eccentric exercise-induced muscle damage. 109.pp.1102–1108, 2010.
  • Beaton L.J., Allan D.A., Tarnopolsky M.A., Tiidus P.M., and Phillips S.M., Contraction-induced muscle damage is unaffected by vitamin E supplementation. Medicine and Science in Sports and Exercise 805,2002. 34.pp.798
  • Bloomer R.J., and Fisher-Wellman K.H., Blood oxidative stress biomarkers: influence of sex, exercise training status, and dietary intake. Gender Medicine 5.pp.218- 28, 2008.
  • Brancaccio P., Lippi G., and Maffulli N., Biochemical markers of muscular damage. Clinical Chemistry and Laboratory Medicine 48.pp.757-67, 2010.
  • Brancaccio P., Maffulli N., and Limongelli FM., Creatine kinase monitoring in sport medicine. British Medical Bulletin 81-82 (1).pp.209-230, 2007.
  • Carlsohn A., Rohn S., Mayer F. and Schweigert F.J., Physical activity, antioxidant status, and protein modification in adolescent athletes. Science in Sports and Exercise 42.pp.1131-9, 2010.
  • Demirbağ R., Yılmaz R., Güzel S., Çelik H., Koçyiğit A., and Özcan E., Effects of treadmill exercise test on oxidative/antioxidative parameters and DNA damage. Anadolu Kardiyoloji Dergisi 6.pp.135-40, 2006.
  • Dieli-Conwright C.M., Spektor T.M., Rice J.C., Sattler F.R., and Schroeder, E.T. Hormone therapy attenuates exercise-induced postmenopausal women. Journal of Applied Physiology 107.pp.853-858, 2009. muscle damage in
  • Durnin J.V., and Womersley J., Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. The British Journal of Nutrition 32.pp.77-97, 1974.
  • Evans W.J., Vitamin E, vitamin C, and exercise. The of American Suppl).pp.647-652, 2000. Clinical Nutrition 72(2
  • Fisher-Wellman K., and Bloomer R.J., Acute exercise and oxidative stress: a 30 year history. Dynamic medicine 8.pp.1, 2009.
  • Gupta C., Gupta P.H., and Singh, B. Effect of Vitamin Supplementation on Exercise Induced Oxidative Stress in Trained Elite Indian Cyclists. American Journal of Biomedical Sciences 1.pp.166-170, 2009.
  • Keong C.C., Singh H.J., and Singh R., Effects of palm vitamin oxidative stress and endurance performance in the heat. Journal of Sports Science and Medicine 5.pp.629-639, 2006. on exercise-induced
  • Kerksick C.M., Kreider R.B., and Willoughby D.S., Intramuscular adaptations to eccentric exercise and antioxidant supplementation. Amino Acids 39.pp.219- 232, 2010.
  • Kürkçü R., Tekin A., Özdağ S., and Akçakoyun F., The effects of regular exercise on oxidative and antioxidative parameters in young wrestlers. African Journal of Pharmacy and Pharmacology 4.pp.244-251, 2010.
  • Lafay S., Jan C., Nardon K., Lemaire B., Ibarra A., Roller M., Houvenaeghel M., Juhel C., and Cara L., Grape extract improves antioxidant status and physical performance in elite male athletes. Journal of Sports Science and Medicine 8.pp.468-480, 2009.
  • Machado M., Zini E.N., Valadao S.D., Amorim M.Z., Barroso Relationship of glomerular filtration rate and serum CK activity after resistance exercise in women. International Urology and Nephrology 44(2).pp.515-21, 2011. W.
  • Mastaloudis A., Traber M.G., Carstensen K., and Widrick J.J., Antioxidants did not prevent muscle damage in response to an ultramarathon run. Medicine and Science in Sports and Exercise 38.pp.72-80, 2006.
  • Moslemi M.K., and Tavanbakhsh S., Selenium- vitamin E supplementation in infertile men: effects on semen parameters and pregnancy rate. International Journal of General Medicine 4.pp.99–104, 2011.
  • Nieman D.C., Henson D.A., Mcanulty S.R., Mcanulty L.S., Morrow J.D., Ahmed A., and Heward C.B., Vitamin E and immunity after the Kona triathlon world championship. Medicine and Science in Sports and Exercise 36.pp.1328-35, 2004.
  • Nuss J.E., Amaning J.K., Bailey C.E., DeFord V.L., Papaconstantinou J., Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle. Aging 1.pp.557-72, 2009. and
  • Overgaard K., Lindstrİm T., Ingemann-Hansen T., and Clausen T., Membrane leakage and increased content of Na+-K+pumps and Ca2+in human muscle after a 100-km run. Journal of Applied Physiology 92.pp.1891-1898, 2002.
  • Powers S.K. and Jackson M.J., Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiological Reviews 88.pp.1243-76, 2008.
  • Saxena R., Garg P. and Jain D., In Vitro anti- oxidant effect of vitamin E on oxidative stress induced due to pesticides in rat erythrocytes. Toxicology Inernational 18.pp.73-6, 2011.
  • Schröder H., Navarro E., Mora J., Galiano D. and Tramullas A., Effects of α -tocopherol, β-carotene and ascorbic acid on oxidative, hormonal and enzymatic exercise stress markers in habitual training activity of professional basketball players. European Journal of Nutrition 2001. 40.pp.178-84
  • Siri. W.E., The gross composition of the body. pages 239-280. In: Lawrence JH, Tobias CA (editors). Academic Press, Inc. Advances in Biological Medical Physics. 4.pp.239-80, 1956.

THE EFFECT OF USING VITAMIN E ON MUSCLE DAMAGE, OXIDANT AND ANTIOXIDANT LEVELS OF RUNNERS PERFORMING ENDURANCE TRAINING1234

Year 2012, Volume: 6 Issue: 3, 251 - 257, 01.12.2012

Abstract

This study was made to research the effect of vitamin E on muscle damage, oxidant and antioxidantlevels of runners. 28 students participated in the study as the experiment group at the age of20,75±1,84 n=16 and the control group n=12 at the age of 20,42±1,78 who are physically active,have the similar physical features and education at Erciyes University. In this study, the same exerciseswere performed on both groups three times a week for thirty days. 400 IU 268 mg vitamin E was givento the athletes in experiment group in every day for 30 days. Nothing was given to the control group.The body weights and the percentage of body fat were measured at the pre and post one monthexercise. Total antioxidant capacity, malondialdehyde, creatine kinase and lactate dehydrogenase weremeasured by making biochemical analyses. While any significant difference on pre-exercise CK andLDH levels, pre and post exercise TAC and MDA levels of experiment and control groups was notfound, there was a significant difference on post exercise CK and LDH levels as a result of theintergroup comparison. As for the intragroup comparison, there was a significant increase on postexercise MDA level of both experiment and control group. This result was thought that the antioxidantcapacity remains incapable; despite usage of vitamin E counter to oxidative stress increasingconnectedly exercise. The reason of this inability in the antioxidant defense system is thought that this isbecause of the amount of daily vitamin E

References

  • Bader N., Bosy-Westphal A., Koch A., Rimbach G., Weimann A., Poulsen H.E., and Müller M.J., Effect of hyperbaric oxygen and vitamin C and E supplementation on biomarkers of oxidative stress in healthy men. The British Journal of Nutrition 98.pp.826-33, 2007.
  • Trombold J.R., Dhindsa M., Lin H.F., and Tanaka H., Arterial stiffening following eccentric exercise-induced muscle damage. 109.pp.1102–1108, 2010.
  • Beaton L.J., Allan D.A., Tarnopolsky M.A., Tiidus P.M., and Phillips S.M., Contraction-induced muscle damage is unaffected by vitamin E supplementation. Medicine and Science in Sports and Exercise 805,2002. 34.pp.798
  • Bloomer R.J., and Fisher-Wellman K.H., Blood oxidative stress biomarkers: influence of sex, exercise training status, and dietary intake. Gender Medicine 5.pp.218- 28, 2008.
  • Brancaccio P., Lippi G., and Maffulli N., Biochemical markers of muscular damage. Clinical Chemistry and Laboratory Medicine 48.pp.757-67, 2010.
  • Brancaccio P., Maffulli N., and Limongelli FM., Creatine kinase monitoring in sport medicine. British Medical Bulletin 81-82 (1).pp.209-230, 2007.
  • Carlsohn A., Rohn S., Mayer F. and Schweigert F.J., Physical activity, antioxidant status, and protein modification in adolescent athletes. Science in Sports and Exercise 42.pp.1131-9, 2010.
  • Demirbağ R., Yılmaz R., Güzel S., Çelik H., Koçyiğit A., and Özcan E., Effects of treadmill exercise test on oxidative/antioxidative parameters and DNA damage. Anadolu Kardiyoloji Dergisi 6.pp.135-40, 2006.
  • Dieli-Conwright C.M., Spektor T.M., Rice J.C., Sattler F.R., and Schroeder, E.T. Hormone therapy attenuates exercise-induced postmenopausal women. Journal of Applied Physiology 107.pp.853-858, 2009. muscle damage in
  • Durnin J.V., and Womersley J., Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. The British Journal of Nutrition 32.pp.77-97, 1974.
  • Evans W.J., Vitamin E, vitamin C, and exercise. The of American Suppl).pp.647-652, 2000. Clinical Nutrition 72(2
  • Fisher-Wellman K., and Bloomer R.J., Acute exercise and oxidative stress: a 30 year history. Dynamic medicine 8.pp.1, 2009.
  • Gupta C., Gupta P.H., and Singh, B. Effect of Vitamin Supplementation on Exercise Induced Oxidative Stress in Trained Elite Indian Cyclists. American Journal of Biomedical Sciences 1.pp.166-170, 2009.
  • Keong C.C., Singh H.J., and Singh R., Effects of palm vitamin oxidative stress and endurance performance in the heat. Journal of Sports Science and Medicine 5.pp.629-639, 2006. on exercise-induced
  • Kerksick C.M., Kreider R.B., and Willoughby D.S., Intramuscular adaptations to eccentric exercise and antioxidant supplementation. Amino Acids 39.pp.219- 232, 2010.
  • Kürkçü R., Tekin A., Özdağ S., and Akçakoyun F., The effects of regular exercise on oxidative and antioxidative parameters in young wrestlers. African Journal of Pharmacy and Pharmacology 4.pp.244-251, 2010.
  • Lafay S., Jan C., Nardon K., Lemaire B., Ibarra A., Roller M., Houvenaeghel M., Juhel C., and Cara L., Grape extract improves antioxidant status and physical performance in elite male athletes. Journal of Sports Science and Medicine 8.pp.468-480, 2009.
  • Machado M., Zini E.N., Valadao S.D., Amorim M.Z., Barroso Relationship of glomerular filtration rate and serum CK activity after resistance exercise in women. International Urology and Nephrology 44(2).pp.515-21, 2011. W.
  • Mastaloudis A., Traber M.G., Carstensen K., and Widrick J.J., Antioxidants did not prevent muscle damage in response to an ultramarathon run. Medicine and Science in Sports and Exercise 38.pp.72-80, 2006.
  • Moslemi M.K., and Tavanbakhsh S., Selenium- vitamin E supplementation in infertile men: effects on semen parameters and pregnancy rate. International Journal of General Medicine 4.pp.99–104, 2011.
  • Nieman D.C., Henson D.A., Mcanulty S.R., Mcanulty L.S., Morrow J.D., Ahmed A., and Heward C.B., Vitamin E and immunity after the Kona triathlon world championship. Medicine and Science in Sports and Exercise 36.pp.1328-35, 2004.
  • Nuss J.E., Amaning J.K., Bailey C.E., DeFord V.L., Papaconstantinou J., Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle. Aging 1.pp.557-72, 2009. and
  • Overgaard K., Lindstrİm T., Ingemann-Hansen T., and Clausen T., Membrane leakage and increased content of Na+-K+pumps and Ca2+in human muscle after a 100-km run. Journal of Applied Physiology 92.pp.1891-1898, 2002.
  • Powers S.K. and Jackson M.J., Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiological Reviews 88.pp.1243-76, 2008.
  • Saxena R., Garg P. and Jain D., In Vitro anti- oxidant effect of vitamin E on oxidative stress induced due to pesticides in rat erythrocytes. Toxicology Inernational 18.pp.73-6, 2011.
  • Schröder H., Navarro E., Mora J., Galiano D. and Tramullas A., Effects of α -tocopherol, β-carotene and ascorbic acid on oxidative, hormonal and enzymatic exercise stress markers in habitual training activity of professional basketball players. European Journal of Nutrition 2001. 40.pp.178-84
  • Siri. W.E., The gross composition of the body. pages 239-280. In: Lawrence JH, Tobias CA (editors). Academic Press, Inc. Advances in Biological Medical Physics. 4.pp.239-80, 1956.
There are 27 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Nazmi Sarıtaş This is me

Betül Coşkun This is me

Cevat Yazıcı This is me

Serdar Büyükipekçi This is me

Kadir Yıldız This is me

Mehmet Yardımcı This is me

Publication Date December 1, 2012
Published in Issue Year 2012 Volume: 6 Issue: 3

Cite

APA Sarıtaş, N., Coşkun, B., Yazıcı, C., Büyükipekçi, S., et al. (2012). THE EFFECT OF USING VITAMIN E ON MUSCLE DAMAGE, OXIDANT AND ANTIOXIDANT LEVELS OF RUNNERS PERFORMING ENDURANCE TRAINING1234. Beden Eğitimi Ve Spor Bilimleri Dergisi, 6(3), 251-257.

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