Year 2020, Volume 3 , Issue 1, Pages 8 - 11 2020-01-01

Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis

Sevilay Ozmen [1] , Havva Tugba Kiper Yılmaz [2] , İlknur Calık [3] , Yusuf Can [4] , Özge Timur [5] , Şenay Arıkan Durmaz [6] , Eşref Kabalar [7] , Ayşe Çarlıoğlu [8] , Kenan Çadırcı [9] , Aykut Turhan [10]


The most endocrinologists in routine practice are used to Bethesda classification for evaluation of thyroid nodule in fine needle aspiration biopsy (FNA). It is accepted that FNA biopsy is an accurate diagnostic and gold standard test. However, false-positive diagnosis may sometimes occur as a patient with a ‘malign’ lesion is found incorrectly rather than an actually benign lesion on histological examination. Hashimoto’s thyroiditis probably is the most common cause of false-positive cytology. The aims of present study evaluate retrospectively postoperatively biopsy results in patients with Hashimoto disease have a thyroidectomy. Results of totally 29 patients with Hashimoto thyroiditis achieved from our hospital records. All of the patients had undergone totally or subtotals thyroidectomy. We are-evaluated retrospectively biopsy results postoperatively. We compared their preoperative FNA results. We detected 24.1% papillary thyroid cancer in seven patients (mean age 45.5±11.9 year), 44.8% nodular goitre in 13 patients (mean age 45.8±4.9 year), 13.7% adenomatous nodule in four patients (mean age 43.5±14.4 year), 3.4% hurtle cell adenoma in one patient with 56 years old. But, 14% in four patients with Hashimoto thyroiditis (mean age 41.5±13.1 year) were redundantly operated due to atypia of undetermined significance in FNA. Although Hashimoto disease is a benign diagnosis, its misclassification as atypia of undetermined significance in FNA accounts for some false-positive errors. The cytopathologists can frequently be interpreted as atypia of undetermined significance instead of Hashimoto’s thyroiditis. Therefore, result of atypia of undetermined significance in FNA may lead unnecessarily concern among with the endocrinologists. More importantly, our results demonstrated that high papillary thyroid cancer rate was found postoperatively in suspicious nodules evolved background Hashimoto thyroiditis.

Hashimoto thyroiditis, Nodules, Fine needle aspiration biopsy, Papillary thyroid cancer
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Primary Language en
Subjects General and Internal Medicine
Journal Section Articles
Authors

Orcid: 0000-0002-1973-6101
Author: Sevilay Ozmen
Institution: ATATÜRK ÜNİVERSİTESİ, TIP FAKÜLTESİ, TIP PR.
Country: Turkey


Orcid: 0000-0003-3072-7190
Author: Havva Tugba Kiper Yılmaz (Primary Author)
Institution: DAHİLİ TIP BİLİMLERİ BÖLÜMÜ
Country: Turkey


Orcid: 0000-0003-2160-7453
Author: İlknur Calık
Institution: UNIVERSITY OF HEALTH SCIENCES, ERZURUM REGION HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF MEDICAL PATHOLOGY
Country: Turkey


Orcid: 0000-0003-3686-9835
Author: Yusuf Can
Institution: UNIVERSITY OF HEALTH SCIENCES, ERZURUM REGION HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF MEDICAL PATHOLOGY
Country: Turkey


Orcid: 0000-0002-7296-5536
Author: Özge Timur
Institution: DAHİLİ TIP BİLİMLERİ BÖLÜMÜ
Country: Turkey


Orcid: 0000-0001-7982-3031
Author: Şenay Arıkan Durmaz
Institution: KIRIKKALE ÜNİVERSİTESİ
Country: Turkey


Orcid: 0000-0002-3463-3864
Author: Eşref Kabalar
Institution: University of Health Science, Erzurum Region Health Training and Reseource Hospital
Country: Turkey


Orcid: 0000-0002-5622-9563
Author: Ayşe Çarlıoğlu
Institution: DAHİLİ TIP BİLİMLERİ BÖLÜMÜ
Country: Turkey


Orcid: 0000-0002-2765-4288
Author: Kenan Çadırcı
Country: Turkey


Orcid: 0000-0002-2535-9816
Author: Aykut Turhan

Dates

Publication Date : January 1, 2020

Bibtex @research article { bshealthscience584096, journal = {Black Sea Journal of Health Science}, issn = {}, eissn = {2619-9041}, address = {bsjhealthsci@blackseapublishers.com}, publisher = {Cem TIRINK}, year = {2020}, volume = {3}, pages = {8 - 11}, doi = {}, title = {Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis}, key = {cite}, author = {Ozmen, Sevilay and Kiper Yılmaz, Havva Tugba and Calık, İlknur and Can, Yusuf and Timur, Özge and Arıkan Durmaz, Şenay and Kabalar, Eşref and Çarlıoğlu, Ayşe and Çadırcı, Kenan and Turhan, Aykut} }
APA Ozmen, S , Kiper Yılmaz, H , Calık, İ , Can, Y , Timur, Ö , Arıkan Durmaz, Ş , Kabalar, E , Çarlıoğlu, A , Çadırcı, K , Turhan, A . (2020). Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis. Black Sea Journal of Health Science , 3 (1) , 8-11 . Retrieved from https://dergipark.org.tr/en/pub/bshealthscience/issue/49535/584096
MLA Ozmen, S , Kiper Yılmaz, H , Calık, İ , Can, Y , Timur, Ö , Arıkan Durmaz, Ş , Kabalar, E , Çarlıoğlu, A , Çadırcı, K , Turhan, A . "Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis". Black Sea Journal of Health Science 3 (2020 ): 8-11 <https://dergipark.org.tr/en/pub/bshealthscience/issue/49535/584096>
Chicago Ozmen, S , Kiper Yılmaz, H , Calık, İ , Can, Y , Timur, Ö , Arıkan Durmaz, Ş , Kabalar, E , Çarlıoğlu, A , Çadırcı, K , Turhan, A . "Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis". Black Sea Journal of Health Science 3 (2020 ): 8-11
RIS TY - JOUR T1 - Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis AU - Sevilay Ozmen , Havva Tugba Kiper Yılmaz , İlknur Calık , Yusuf Can , Özge Timur , Şenay Arıkan Durmaz , Eşref Kabalar , Ayşe Çarlıoğlu , Kenan Çadırcı , Aykut Turhan Y1 - 2020 PY - 2020 N1 - DO - T2 - Black Sea Journal of Health Science JF - Journal JO - JOR SP - 8 EP - 11 VL - 3 IS - 1 SN - -2619-9041 M3 - UR - Y2 - 2019 ER -
EndNote %0 Black Sea Journal of Health Science Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis %A Sevilay Ozmen , Havva Tugba Kiper Yılmaz , İlknur Calık , Yusuf Can , Özge Timur , Şenay Arıkan Durmaz , Eşref Kabalar , Ayşe Çarlıoğlu , Kenan Çadırcı , Aykut Turhan %T Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis %D 2020 %J Black Sea Journal of Health Science %P -2619-9041 %V 3 %N 1 %R %U
ISNAD Ozmen, Sevilay , Kiper Yılmaz, Havva Tugba , Calık, İlknur , Can, Yusuf , Timur, Özge , Arıkan Durmaz, Şenay , Kabalar, Eşref , Çarlıoğlu, Ayşe , Çadırcı, Kenan , Turhan, Aykut . "Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis". Black Sea Journal of Health Science 3 / 1 (January 2020): 8-11 .
AMA Ozmen S , Kiper Yılmaz H , Calık İ , Can Y , Timur Ö , Arıkan Durmaz Ş , Kabalar E , Çarlıoğlu A , Çadırcı K , Turhan A . Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis. BSJ Health Sci.. 2020; 3(1): 8-11.
Vancouver Ozmen S , Kiper Yılmaz H , Calık İ , Can Y , Timur Ö , Arıkan Durmaz Ş , Kabalar E , Çarlıoğlu A , Çadırcı K , Turhan A . Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis. Black Sea Journal of Health Science. 2020; 3(1): 11-8.