Renal İskemi-Reperfüzyonu Sırasında Sıçan Böbreğinde Oluşan Oksidatif Stres Hasarına Silimarin Etkisi

Year 2010, Volume: 7 Issue: 1, - , 01.02.2010

Hakan Şentürk Dürdane Kolankaya Yalçın Şahin

Abstract

Renal ischemia reperfusion injury is the most common causes of acute renal
failure. Silybum marianum L. Gaertn. (milk thistle) is a plant which belongs to Asteraceae
family. Silymarin is a plant derived flavonoid which is extracted from the seeds of the S.
marianum L. In this study, we investigated the protective effect of silymarin during the
experimental renal ischemia reperfusion injury in rats histologically and biochemically.

Keywords

Ischemia-reperfusion, kidney, silymarin, rat

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