A Study on Total Phenolic and Flavonoid Content, Antioxidant, Toxicity, and Antihelmintic Activities of Methanol Extracts of Crocus cancellatus subsp. lycuis

Year 2023, Volume: 19 Issue: 1, 73 - 78, 28.03.2023

Mehlika Alper , Mehmet Özgür Atay , Olcay Ceylan , Ramazan Mammadov

https://doi.org/10.18466/cbayarfbe.1111317

https://izlik.org/JA78FR39UU

Abstract

The present study was planned to assess total phenolic and flavonoid content and some biological properties (antioxidant, toxicity, and antihelmintic) of the methanol extracts of Crocus cancellatus subsp. lycuis from Muğla province (Turkey) for the first time. Total phenolic (2.08±0.06 mg GAE/g) and total flavonoid (3.63±0.09 mg QE/g) contents of the aerial part extract were higher than the bulb extract. The aerial part extract (IC50 value: 0,86±0,03 mg/mL, IC50 value: 0,26±0,003 mg/mL, 0,77±0,007 mg TE/g, and 5,92±0,30 mg TE/g, respectively) was determined to exhibit the higher activity than that of bulb parts extract in the assays shortly named as DPPH, ABTS, FRAP and CUPRAC carried out to examine the antioxidant activities of the extracts. Both extracts were observed to be effective on brine shrimp and to have anthelmintic activity. According to these results, Crocus cancellatus subsp. lycuis may be paid attention as a good source for the pharmaceutical and food industries.

Keywords

Anthelmintic , Antioxidant , Brine shrimp , Crocus , Flavonoid , Phenolic

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