Chemical Composition and Antibacterial Activities of Corylus avellana L. Bioproducts Grown in Giresun-Türkiye

Abstract

Hazelnut has become an important commercial product in recent years due to its worldwide applications in the pharmaceutical industry as well as in the confectionery and food industry. In addition, hazelnut shell is a waste material obtained after hazelnut harvest and mainly used as heating sources. However, its bioproducts are essentially a very important phytochemical source. In this study, the composition of phenolic compounds, carotenoids, tocopherols and fatty acids of different bioproducts of hazelnut plant were investigated. The highest phenolic compound content (2630.84 µg/g), and lutein amount (73.05 µg/g) were determined in green leafy cover. The major fatty acids were found to be as oleic acid (81.493%), linoleic acid (7.778%) and palmitic acid (6.408%), respectively. Total tocopherol concentration of hazelnut kernel was determined as 364.1 µg/g. In the present study, the antibacterial activity of hazelnut bioproducts was determined using eight pathogenic bacteria. They showed strong antimicrobial activity against the Gram (+) and Gram (-) bacteria which might be attributed to the rich phytochemical composition of hazelnut bioproducts. This work comprehensively summarized the chemical composition of hazelnut bioproducts and their antibacterial activity potential grown in Giresun-Türkiye region which had an important place in the global market.

Keywords

• Corylus Avellana
• hazelnut
• bioproducts
• chemical composition
• antimicrobial activity

Supporting Institution

Giresun Üniversitesi

Project Number

FEN-BAP-A-150219-15

Thanks

Karaerler Machine

References

1. [1]. Shahidi, F, Alasalvar, C, Liyana-Pathirana, CM. 2007. Antioxidant phytochemicals in hazelnut kernel (Corylus avellana L.) and hazelnut byproducts. Journal of Agricultural and Food Chemistry; 55(4), 1212-20.
2. [2]. Shataer, D, Abdulla, R, Ma, QL, Liu, GY, Aisa, HA. 2020. Chemical Composition of Extract Of Corylus avellana Shells. Chemistry of Natural Compounds; 56, 338-340.
3. [3]. Alasalvar, C, Shahidi, F, Liyanapathirana, CM, Ohshima, T. 2003. Turkish Tombul hazelnut (Corylus avellana L.). 1. Compositional characteristics. Journal of Agricultural and Food Chemistry; 51(13), 3790-3796. [4]. Oliveira, I, Sousa, A, Morais, JS, Ferreira, IC, Bento, A, Estevinho, L, Pereira, JA. 2008. Chemical composition, and antioxidant and antimicrobial activities of three hazelnut (Corylus avellana L.) cultivars. Food Chemistry and Toxicology; 46(5), 1801-1807.
4. [5]. Taş, NG, Gökmen, V. 2015a. Bioactive compounds in different hazelnut varieties and their skins. Journal of Food Composition and Analysis; 43, 203-208.
5. [6]. Toprak Mahsulleri Ofisi (TMO) 2020 Yılı Fındık Sektör Raporu; Ankara: TMO 2021. https://www.tmo.gov.tr/Upload/Document/sektorraporlari/findik2020.pdf
6. [7]. Taş, NG, Gökmen, V. 2015b. Profiling triacylglycerols, fatty acids and tocopherols in hazelnut varieties grown in Turkey. Journal of Food Composition and Analysis; 44, 115-121.
7. [8]. Alasalvar, C, Bolling, BW. 2015. Review of nut phytochemicals, fat-soluble bioactives, antioxidant components and health effects. British Journal of Nutrition; 113(2), S68-78.
8. [9]. Alasalvar, C, Shahidi, F. 2008. Tree nuts: Composition, phytochemicals, and health effects: An overview. (pp. 15-24) CRC press.

9. [10]. Brown, R, Ware, L, Tey, S. L. 2022. Effects of Hazelnut Consumption on Cardiometabolic Risk Factors and Acceptance: A Systematic Review. International Journal of Environmental Research and Public Health; 19(5), 2880.
10. [11]. Tey, SL, Brown, RC, Chisholm, AW, Delahunty, CM, Gray, AR, Williams, SM. 2011. Effects of different forms of hazelnuts on blood lipids and alpha-tocopherol concentrations in mildly hypercholesterolemic individuals. European Journal of Clinical Nutrition; 65(1), 117-24.
11. [12]. Schmitzer, V, Slatnar, A, Veberic, R, Stampar, F, Solar, A. 2011. Roasting affects phenolic composition and antioxidative activity of hazelnuts (Corylus avellana L.). Journal of Food Science; 76(1), S14-9.
12. [13]. Balta, MF, Yarilgac, T, Askin, MA, Kucuk, M, Balta, F, Ozrenk, K. 2006. Determination of fatty acid compositions, oil contents and some quality traits of hazelnut genetic resources grown in eastern Anatolia of Turkey. Journal of Food Composition and Analysis; 19(6-7), 681-686.
13. [14]. Durmaz, G, Gokmen, V. 2019. Effect of refining on bioactive composition and oxidative stability of hazelnut oil. Food Research International; 116, 586-591.
14. [15]. Sun, JY, Feng, XN, Lyu, CM, Zhou, S, Liu, ZX. 2022. Effects of different processing methods on the lipid composition of hazelnut oil: a lipidomics analysis. Food Science and Human Wellness; 11(2), 427-435.
15. [16]. Xu, YX, Hanna, MA, Josiah, SJ. 2007. Hybrid hazelnut oil characteristics and its potential oleochemical application. Industrial Crops and Products; 26(1), 69-76.
16. [17]. Cerulli, A, Lauro, G, Masullo, M, Cantone, V, Olas, B, Kontek, B, Nazzaro, F, Bifulco, G, Piacente, S. 2017. Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities. Journal of Natural Products; 80(6), 1703-1713.
17. [18]. Alasalvar, C, Karamac, M, Amarowicz, R, Shahidi, F. 2006. Antioxidant and antiradical activities in extracts of hazelnut kernel (Corylus avellana L.) and hazelnut green leafy cover. Journal of Agricultural and Food Chemistry; 54(13), 4826-32.
18. [19]. Bottone, A, Cerulli, A, D'Urso, G, Masullo, M, Montoro, P, Napolitano, A, Piacente, S. 2019. Plant Specialized Metabolites in Hazelnut (Corylus avellana) Kernel and Byproducts: An Update on Chemistry, Biological Activity, and Analytical Aspects. Planta Medica; 85(11/12), 840-855.
19. [20]. Arcan, I, Yemenicioglu, A. 2009. Antioxidant activity and phenolic content of fresh and dry nuts with or without the seed coat. Journal of Food Composition and Analysis; 22(3), 184-188.
20. [21]. Şahin, S, Tonkaz, T, Yarilgaç, T. 2022. Chemical Composition, Antioxidant Capacity And Total Phenolic Content of Hazelnuts Grown In Different Countries. Tekirdağ Ziraat Fakültesi Dergisi; 19(2), 262-270.
21. [22]. Şeker, ME, Ay, E, Karaçelik, AA, Hüseyinoğlu, R, Efe, D. 2021. First determination of some phenolic compounds and antimicrobial activities ofGeranium ibericum subsp. jubatum: A plant endemic to Turkey. Turkish Journal of Chemistry; 45(1), 60-70.
22. [23]. Celenk, VU, Gumus, ZP, Argon, ZU, Buyukhelvacigil, M, Karasulu, E. 2018. Analysis of chemical compositions of 15 different cold-pressed oils produced in Turkey: a case study of tocopherol and fatty acid analysis. Journal of the Turkish Chemical Society Section A: Chemistry; 5(1), 1-18.
23. [24]. Aksoz, E, Korkut, O, Aksit, D, Gokbulut, C. 2020. Vitamin E (α‐, β+ γ‐and δ‐tocopherol) levels in plant oils. Flavour and Fragrance Journal; 35(5), 504-510.
24. [25]. Górnaś, P, Soliven, A, Segliņa, D. 2015. Seed oils recovered from industrial fruit by‐products are a rich source of tocopherols and tocotrienols: Rapid separation of α/β/γ/δ homologues by RP‐HPLC/FLD. European Journal of Lipid Science and Technology; 117(6), 773-777.
25. [26]. Erdoğan, A, Çağır, A, Dalay, MC, Eroğlu, AE. 2015. Composition of carotenoids in Scenedesmus protuberans: Application of chromatographic and spectroscopic methods. Food Analytical Methods; 8, 1970-1978.
26. [27]. Gültekin-Özgüven, M, Davarcı, F, Paslı, AA., Demir, N, Özçelik, B. 2015. Determination of phenolic compounds by ultra-high liquid chromatography-tandem mass spectrometry: Applications in nuts. LWT-Food Science and Technology; 64(1), 42-49.
27. [28]. Pelvan, E, Olgun, EO, Karadag, A, Alasalvar, C. 2018. Phenolic profiles and antioxidant activity of Turkish Tombul hazelnut samples (natural, roasted, and roasted hazelnut skin). Food Chemistry; 244, 102-108.
28. [29]. Ciemniewska-Zytkiewicz, H, Verardo, V, Pasini, F, Brys, J, Koczon, P, Caboni, MF. 2015. Determination of lipid and phenolic fraction in two hazelnut (Corylus avellana L.) cultivars grown in Poland. Food Chemistry; 168, 615-22.
29. [30]. Ceylan, O, Sahin, M Avaz, S. 2013. Antibacterial activity of Corylus colurna L.(Betulaceae) and Prunus divaricata Ledep. subsp. divaricata (Rosaceae) from Usak, Turkey.
30. [31]. Yuan, B, Lu, M, Eskridge, KM., Isom, LD, Hanna, M. A. 2018. Extraction, identification, and quantification of antioxidant phenolics from hazelnut (Corylus avellana L.) shells. Food Chemistry; 244, 7-15.
31. [32]. Tüfekci, F, Karataş, Ş. 2018. Determination of geographical origin Turkish hazelnuts according to fatty acid composition. Food Science and Nutrition; 6(3), 557-562.
32. [33]. Bacchetta, L, Aramini, M, Zini, A., Di Giammatteo, V, Spera, D, Drogoudi, P, Rovira, M, Silva, AP, Solar, A, Botta, R. 2013. Fatty acids and alpha-tocopherol composition in hazelnut (Corylus avellana L.): a chemometric approach to emphasize the quality of European germplasm. Euphytica; 191, 57-73.
33. [34]. Parcerisa, J, Richardson, DG, Rafecas, M, Codony, R, Boatella, J. 1998. Fatty acid, tocopherol and sterol content of some hazelnut varieties (Corylus avellana L.) harvested in Oregon (USA). Journal of Chromatography A; 805(1-2), 259-268.
34. [35]. Kornsteiner, M, Wagner, KH, Elmadfa, I. 2006. Tocopherols and total phenolics in 10 different nut types. Food Chemistry; 98(2), 381-387.
35. [36]. Stuetz, W, Schlormann, W, Glei, M. 2017. B-vitamins, carotenoids and alpha-/gamma-tocopherol in raw and roasted nuts. Food Chemistry; 221, 222-227.
36. [37]. Al Juhaimi, F, Ozcan, MM, Ghafoor, K, Babiker, EE, Hussain, S. 2018. Comparison of cold-pressing and soxhlet extraction systems for bioactive compounds, antioxidant properties, polyphenols, fatty acids and tocopherols in eight nut oils. Journal of Food Science and Technology; 55, 3163-3173.
37. [38]. Köksal, Aİ, Artik, N, Şimşek, A, Güneş, N. 2006. Nutrient composition of hazelnut (Corylus avellana L.) varieties cultivated in Turkey. Food Chemistry; 99(3), 509-515.
38. [39]. Kirbaslar, FG, Türker, G, Özsoy-Günes, Z, Ünal, M, Dülger, B, Ertas, E, Kizilkaya, B. 2012. Evaluation of Fatty Acid Composition, Antioxidant and Antimicrobial Activity, Mineral Composition and Calorie Values of Some Nuts and Seeds fromTurkey. Records of Natural Products; 6(4), 339.
39. [40]. Oliveira, I, Sousa, A, Valentao, P, Andrade, PB, Ferreira, ICFR, Ferreres, F, Bento, A, Seabra, R, Estevinho, L, Pereira, JA. 2007. Hazel (Corylus avellana L.) leaves as source of antimicrobial and antioxidative compounds. Food Chemistry; 105(3), 1018-1025.
40. [41]. Özaslan, M, Oğuzkan, SB, Uğraş, S, Merve, C, Ayşe, U, Ülger, S, Üzmez, Ş, Karagül, B, Kiliç, İH, Uğraş, Hİ. 2016. Fındık (Corylus Avellana L.) yeşil kabuk ve yaprak ekstraklarında biyolojik aktivite tayini. KSÜ Doğa Bilimleri Dergisi; 19(4), 373-378.
41. [42]. Amarowicz, R, Dykes, GA, Pegg, RB. 2008. Antibacterial activity of tannin constituents from Phaseolus vulgaris, Fagoypyrum esculentum, Corylus avellana and Juglans nigra. Fitoterapia; 79(3), 217-9.
42. [43]. Proestos, C, Chorianopoulos, N, Nychas, GJ, Komaitis, M. 2005. RP-HPLC analysis of the phenolic compounds of plant extracts. investigation of their antioxidant capacity and antimicrobial activity. Journal of Agricultural and Food Chemistry; 53(4), 1190-5.
43. [44]. Caligiani, A, Coisson, JD, Travaglia, F, Acquotti, D, Palla, G, Palla, L, Arlorio, M. 2014. Application of (1)H NMR for the characterisation and authentication of ''Tonda Gentile Trilobata" hazelnuts from Piedmont (Italy). Food Chemistry; 148, 77-85.
44. [45]. Bachmann, R, Klockmann, S, Haerdter, J, Fischer, M, Hackl, T. 2018. (1)H NMR Spectroscopy for Determination of the Geographical Origin of Hazelnuts. Journal of Agricultural and Food Chemistry; 66(44), 11873-11879.