Üzüm ve Üzüm Ürünlerinden Okratoksin A Sorunu

Abstract

Keywords

• -

Üzüm ve Üzüm Ürünlerinden Okratoksin A Sorunu

Abstract

Okratoksin baz Aspergillus ve Penicillium türleri taraf ndan üretilen bir mikotoksindir.En s k görülen ve en toksik olan tipi Okratoksin A d r. nsan sa lA n n kanserojen, genotoksik, teratojenik, immunotoksik ve nefrotoksik etkileri ortaya konmu tur. nsanlarda böbrek hastal klar na ve kansere neden olur. Okratoksin A tah llar, sebzeler, kurutulmu meyveler, f nd k, et ve baz içeceklerde tespit edilmi tir.Son y llarda arap, sirke, kuru üzüm ve üzüm suyunun da önemli miktarlarda OTA içerdi i belirlenmi tir. Üzüm ve ürünlerinde OTA üretti i bilinen en yayg n türler A. Carbonarius, A. Niger ve A. Tubingensis tir. OTA kontaminasyonunun önlenmesi veya azalt lmas için üzüm ürünlerinin üretimi ve hasad s ras nda iyi tar m uygulamalar ve HACCP ilkeleri uygulanmal d r

Keywords

• Okratoksin A, üzüm, üzüm suyu, kuru üzüm, arap

References

1. Steyn, P. S., dihydroisocoumarins. isolation, separation and purification , V. Betina (Ed), pp. 183- 216. Elsevier Science, (1984).
2. Zimmerli, B., Dick, R., Ochratoxin A in table wine and grape juice: Occurrence and risk assessment , Food Additives and Contaminants, 13: 668 (1996).
3. Anonymous, Codex Alimentarious situation review of contaminants and toxins in foods. Annex IV- B, 5, 21. Ochratoxin A, 46, (1998).
4. International Agency for Research on Cancer (IARC), Some naturally occurring substances, food items constituents, heterocyclic aromatic amines mycotoxins. In IARC Monographs on Evaluation of Carcinogenic Risks to Humans, Vol 56 pp: 489- , IARC, Lyon, France, (1993).
5. Codex Alimentarious Commission, Codex Committee on Food Additives and Contaminants, st session, The Hague, the Netherlands, 22- 26 March, (1999).
6. Varga, J., Kazakiewics, Z., Ochratoxin A in grapes and grape derived productsTrends in Food Science and Technology, 1- 10 (2005).
7. Pedzinger, E., Weidenbach, A., Myctoxins in the food chain: the role of Ochratoxins Production Science, 76: 245- 250 (2002). Livestock
8. Battilani, P., Pietri, A., Ochratoxin A in grapes and wine : 639- 643 (2002).

9. Anl , E., Çabuk, B., Vural, N., Ba p nar, E., Ochratoxin A in Turkish Wine Biochemistry, 29: 611- 623 (2005). Journal of Food
10. Battilani, P., Giorni, P., Pietry, A., Epidemiology of toxin producing fungi and Ochratoxin A occurrence in grape Journal of Plant Pathology, 109: 715- 722 (2003). European
11. Majerus, P., Bresch, H., Otteneder, H., Ochratoxin A in wines, fruit juices and seasonings Archives für Lebensmittelhygiene, 51: 97 (2000).
12. Markaki, P., Delpont-Binet, Grosso, F., Dragacci, S., Determination of ochratoxin A in red wine and vinegar by immunoaffinity high pressure liquid chromatographyJournal of Food Protection, , 533-537 (2001).
13. Ar c , M., Gümü , T., Kara, F., The fate of Ochratoxin A during the pekmez production from mouldy grapes Food Control, 15: 597- 600 (2004). Miraglia, M., Brera, C., dietary intake of Ochratoxin A by the population of EU member states cooperation. Reports of exports participating in
14. SCOOP Task 3. 2. 7. Directorate- General Health and Consumer Protection, Rome, Italy (2002).
15. MacDonald S., Wilson, P., Barnes, K., Damant, A., Massey, R., Mortby, E., Shepherd, M. J., Ochratoxin A in dried vine fruit: method development and survey Contaminants, 16: 253- 260 (1999). Food Additives and Dalcero, A. M., Survey of mycoflora and ochratoxin A in dried vine fruits from Argentina marketsLetters in Applied Microbiology, 39: 326- (2004).
16. Ta kaya, B., Kuru Üzüm. Tar msal Ekonomi Ara t rma Enstitüsü TEAE- BAKI , 3: 1-4 (2003).
17. T.C. Ba bakanl k Devlet Planlama Te kilat Müste arl okratoksin a olu umunun incelenmesi ve potansiyel okratoksijenik identifikasyonu Yürütücü: Rengin Eltem. Bornova üzümlerde küflerin izolasyonu ve Proje Kod No. 1999 DPT/001. zmir 2004.
18. Çelik, H., Marasal , B., Söylemezo lu, G., Tangolar, S., Gündüz, M., Ba c l kta üretim hedefleri (2003). www.bagcilik.org/dosyalar/uretim_hedefleri.pdf.
19. Visconti, A., Pascale, M., Centonze, G., Determination of ochratoxin A in wine by means of immunoaffinity column clean- up and high- performance liquid chromatography Journal of Chromatography A, 864: 89- 101 (1999)
20. Anonymous., Amending regulation No /2005 of 26 January 2005 amending regulation
21. (EC) No 466/2001 as regards ochratoxin A. Official
22. Journal of the European Union (2005). Geli Tarihi: 13/03/2006 Kabul Tarihi: 27/04/2006