Synthesis and Characterization of Schiff Base 1-Amino-4-methylpiperazine Derivatives

Year 2016, Volume: 12 Issue: 3, 375 - 392, 26.12.2016

Emriye Ay

Abstract

In this study, potentially
biological active new Schiff bases were synthesized in good yield from
1-amino-4-methylpiperazine and aromatic aldehydes as a 3-nitro-benzaldehyde, 4-fluoro-benzaldehyde,
3,4,5-trimethoxybenzaldehyde, 3,4-dichlorobenzaldehyde,
4-diethylaminobenzaldehyde, 2,5-dimethoxybenzaldehyde and 5-nitro-2-furaldehyde
and structure of the synthesized
compounds were elucidated by FTIR, LC-MS, ¹H-NMR and ¹³C-NMR
techniques.

Keywords

1-Amino-4-methylpiperazine, aromatic aldehydes, hydrazone, imine, Schiff base

References

• Qin W., Long S., Panunzio M., and Biondi S., Schiff Bases: A Short Survey on an Evergreen Chemistry Tool, Molecules, 2013; 18, 12264-12289.