Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion

Year 2017, Volume: 13 Issue: 4, 943 - 947, 29.12.2017

Çinel Köksal Karayıldırım

https://doi.org/10.18466/cbayarfbe.370370

Cited By: 8

Abstract

Natural products used in
the traditional systems of medicine exhibit a various and promising resource in
human health. However, these products are often characterized for their
chemical composition as well as mechanisms of action. Considering the bacterial
infections play an important role in human diseases, it is necessary to develop
new antibacterial herbal products. The aim of this study was to isolation and
structural identification of hesperidin from Citrus sinensis L. and to formulate hesperidin loaded to
water-in-oil (w/o) microemulsion as an inovative formulation for bactericidal treatment.
This present study indicates that hesperidin microemulsion has antibacterial
activity against various types of bacteria according to MIC method. All strains
were showed logaritmic reduction. These findings indicated that the
microemulsion as a drug carrier, especially hesperidin formulation, may be used
as an effective antibacterial therapy.

Keywords

Citrus sinensis, Hesperidin, Antibacterial activity, Microemulsion, MIC

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