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Year 2020, Volume: 2 Issue: 3, 56 - 60, 31.12.2020

Abstract

References

  • REFERENCES: 1. Mamalis N. Endophthalmitis. J Cataract Refract Surg. 2002; 28 (5): 729–730 . 2. Smith SR, Kroll AJ, Lou PL, Ryan EA. Endogenous bacterial and fungal endophthalmitis. Int Ophthalmol Clin. 2007; 47 (2): 173–183. 3. Moloney TP, Park J. Microbiological isolates and antibiotic sensitivities in culture-proven endophthalmitis: a 15-year review. Br J Ophthalmol. 2014; 98 (11): 1492–1497. 4. Verbraeken H. Treatment of postoperative endophthalmitis. Ophthalmologica. 1995; 209 (3): 165– 171. 5. Wykoff CC, Parrott MB, Flynn HW, Jr, Shi W, Miller D, Alfonso EC. Nosocomial acute-onset postoperative endophthalmitis at a University Teaching Hospital (2002–2009) Am J Ophthalmol. 2010; 150 (3): 392. 6. Miller JJ, Scott IU, Flynn HW, Jr, Smiddy WE, Newton J, Miller D. Acute-onset endophthalmitis after cataract surgery (2000–2004): incidence, clinical settings, and visual acuity outcomes after treatment. Am J Ophthalmol. 2005; 139 (6): 983–987.
  • 7. Ravindran RD, Venkatesh R, Chang DF, Sengupta S, Gyatsho J, Talwar B. Incidence of post-cataract endophthalmitis at Aravind Eye Hospital: outcomes of more than 42,000 consecutive cases using standardized sterilization and prophylaxis protocols. J Cataract Refract Surg. 2009; 35 (4): 629–636. 8. Freeman EE, Roy-Gagnon M-H, Fortin E, Gauthier D, Popescu M, Boisjoly H. Rate of endophthalmitis after cataract surgery in Quebec, Canada, 1996–2005. Arch Ophthalmol. 2010; 128 (2): 230–234. 9. Moshirfar M, Feiz V, Vitale AT, Wegelin JA, Basavanthappa S, Wolsey DH. Endophthalmitis after uncomplicated cataract surgery with the use of fourthgeneration fluoroquinolones: a retrospective observational case series. Ophthalmology, 2007; 114 (4): 686–691. 10. Jensen MK, Fiscella RG, Moshirfar M, Mooney B. Third- and fourth-generation fluoroquinolones: retrospective comparison of endophthalmitis after cataract surgery performed over 10 years. J Cataract Refract Surg. 2008; 34 (9): 1460–1467. 11. Friling E, Lundström M, Stenevi U, Montan P. Six-year incidence of endophthalmitis after cataract surgery: Swedish national study. J Cataract Refract Surg. 2013; 39 (1): 15–21. 12. Keay L, Gower EW, Cassard SD, Tielsch JM, Schein OD. Postcataract surgery endophthalmitis in the United States: analysis of the complete 2003 to 2004 Medicare database of cataract surgeries. Ophthalmology, 2012; 119 (5): 914–922. 13. Alharbi SS, Alrajhi A, Alkahtani E. Endophthalmitis following keratoplasty: incidence, microbial profile, visual and structural outcomes. Ocul Immunol Inflamm. 2013; 22 (3): 218–223. 14. Taban M, Behrens A, Newcomb RL, Nobe MY, McDonnell PJ. Incidence of acute endophthalmitis following penetrating keratoplasty: a systematic review. Arch Ophthalmol. 2005; 123 (5): 605–609. 15. Tay E, Bainbridge J, da Cruz L. Subretinal abscess after scleral buckling surgery: a rare risk of retinal surgery. Can J Ophthalmol. 2007; 42 (1): 141–142. 16. Al-Torbak AA, Al-Shahwan S, Al-Jadaan I, AlHommadi A, Edward DP. Endophthalmitis associated with the Ahmed glaucoma valve implant. Br J Ophthalmol. 2005; 89 (4): 454–458. 17. Endophthalmitis Vitrectomy Study Group Results of the endophthalmitis vitrectomy study: a randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis. Arch Ophthalmol. 1995; 113 (12): 1479–1496. 18. Ozadamar A, Aras C, Ozturk R, Akin E, karacorlu M, Ercikan C. In vitro antimicrobial activity of silicone oil against endophthalmitis-causing agents. Retina. 1999; 19 (2): 122–126. 19. Azad R, Ravi K, Talwar D, Rajpal, Kumar N. Pars plana vitrectomy with and without silicone oil tamponade in post-traumatic endophthalmitis. Graefe’s Arch ClinExp Ophthalmol. 2003; 241 (6): 478–483. 20. Do T, Hon D, Aung T, Hien ND, Cowan CL Jr. Bacterial endogenous endophthalmitis in Vietnam: a randomized controlled trial comparing vitrectomy with silicone oil versus vitrectomy alone. Clin Ophthalmol. 2014 Aug 28; 8: 1633-40. 21. Wong JS, Chan TK, Lee HM, et al. Endogenous bacterial endophthalmitis. Ophthalmology, 2000; 107 (8): 1483–1491 22. Jackson TL, Eykyn JS, Graham EM, Graham EM, Stanford MR. Endogenous bacterial endophthalmitis: a 17-year prospective study and review of 267 reported cases. Surv Opthalmol. 2003; 48 (4): 403–423.
  • 23. Yoon YH, Lee SU, Sohn JH, Lee SE. Result of early vitrectomy for endogenous Klebsiella pneumonia endophthalmitis. Retina. 2003; 23 (3): 366–370. 24. Kuhn F, Gini G. Ten years after... are findings of the Endophthalmitis Vitrectomy Study still relevant today? Graefe’s Arch Clin Exp Ophthalmol. 2005; 243 (12): 1197–1199. 25. Cowley M, Conway BP, Campochiaro PA, kaiser D, Gaskin H. Clinical risk factors for proliferative vitreo retinopathy. Arch Ophthalmol. 1989; 107 (8): 1147–1151 26. Cowley M, Conway BP, Campochiaro PA, kaiser D, Gaskin H. Clinical risk factors for proliferative vitreoretinopathy. Arch Ophthalmol. 1989; 107 (8): 1147–1151

Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis with or without Silicone Oil

Year 2020, Volume: 2 Issue: 3, 56 - 60, 31.12.2020

Abstract

Purpose: To evaluate the anatomical and functional outcomes of pars plana vitrectomy (PPV) in acute post operative endophthalmitis with or without endotamponade.
Material and Methods: Quasi experimental study was conducted at Lahore General hospital, Lahore. One hundred ninety patients of acute post-surgical endophthalmitis were included in the study. Patients were randomized into two groups after no clinical improvement was seen post primary vitreous tap and intravitreal vancomycin and ceftazidime. In group 1 patients undergoing PPV with endotamponade (silicon oil) were included while in group 2 patients undergoing PPV without endotamponade were included. Study was divided in two phases. In first phase 30 patients underwent PPV without endotamponade and 30 patients with endotamponade. Considering the results of phase 1, rest of the 130 patients underwent PPV with endotamponade in phase 2. Removal of silicone oil in all patients was done at 12 weeks.
Results: In first phase of study 23 (76.66%) patients in Group 2 showed retinal detachment within four weeks of follow up, while no patient (0%) in Group 1 showed retinal detachment within four weeks of follow up. Later 6 (7.31%) patients in group 1 showed retinal detachment within four weeks of silicone oil removal. In second phase all 130 patients showed no retinal detachment after undergoing PPV with endotamponade as in group 1. Overall 160 patients underwent PPV with endotamponade including first and second phase and only 6 patients got retinal detachment.
Conclusion: Early PPV with endotamponade should be preferred to PPV without endotamponade in cases of acute postoperative endophthalmitis due to statistically significant improvement in anatomical and functional outcomes.

References

  • REFERENCES: 1. Mamalis N. Endophthalmitis. J Cataract Refract Surg. 2002; 28 (5): 729–730 . 2. Smith SR, Kroll AJ, Lou PL, Ryan EA. Endogenous bacterial and fungal endophthalmitis. Int Ophthalmol Clin. 2007; 47 (2): 173–183. 3. Moloney TP, Park J. Microbiological isolates and antibiotic sensitivities in culture-proven endophthalmitis: a 15-year review. Br J Ophthalmol. 2014; 98 (11): 1492–1497. 4. Verbraeken H. Treatment of postoperative endophthalmitis. Ophthalmologica. 1995; 209 (3): 165– 171. 5. Wykoff CC, Parrott MB, Flynn HW, Jr, Shi W, Miller D, Alfonso EC. Nosocomial acute-onset postoperative endophthalmitis at a University Teaching Hospital (2002–2009) Am J Ophthalmol. 2010; 150 (3): 392. 6. Miller JJ, Scott IU, Flynn HW, Jr, Smiddy WE, Newton J, Miller D. Acute-onset endophthalmitis after cataract surgery (2000–2004): incidence, clinical settings, and visual acuity outcomes after treatment. Am J Ophthalmol. 2005; 139 (6): 983–987.
  • 7. Ravindran RD, Venkatesh R, Chang DF, Sengupta S, Gyatsho J, Talwar B. Incidence of post-cataract endophthalmitis at Aravind Eye Hospital: outcomes of more than 42,000 consecutive cases using standardized sterilization and prophylaxis protocols. J Cataract Refract Surg. 2009; 35 (4): 629–636. 8. Freeman EE, Roy-Gagnon M-H, Fortin E, Gauthier D, Popescu M, Boisjoly H. Rate of endophthalmitis after cataract surgery in Quebec, Canada, 1996–2005. Arch Ophthalmol. 2010; 128 (2): 230–234. 9. Moshirfar M, Feiz V, Vitale AT, Wegelin JA, Basavanthappa S, Wolsey DH. Endophthalmitis after uncomplicated cataract surgery with the use of fourthgeneration fluoroquinolones: a retrospective observational case series. Ophthalmology, 2007; 114 (4): 686–691. 10. Jensen MK, Fiscella RG, Moshirfar M, Mooney B. Third- and fourth-generation fluoroquinolones: retrospective comparison of endophthalmitis after cataract surgery performed over 10 years. J Cataract Refract Surg. 2008; 34 (9): 1460–1467. 11. Friling E, Lundström M, Stenevi U, Montan P. Six-year incidence of endophthalmitis after cataract surgery: Swedish national study. J Cataract Refract Surg. 2013; 39 (1): 15–21. 12. Keay L, Gower EW, Cassard SD, Tielsch JM, Schein OD. Postcataract surgery endophthalmitis in the United States: analysis of the complete 2003 to 2004 Medicare database of cataract surgeries. Ophthalmology, 2012; 119 (5): 914–922. 13. Alharbi SS, Alrajhi A, Alkahtani E. Endophthalmitis following keratoplasty: incidence, microbial profile, visual and structural outcomes. Ocul Immunol Inflamm. 2013; 22 (3): 218–223. 14. Taban M, Behrens A, Newcomb RL, Nobe MY, McDonnell PJ. Incidence of acute endophthalmitis following penetrating keratoplasty: a systematic review. Arch Ophthalmol. 2005; 123 (5): 605–609. 15. Tay E, Bainbridge J, da Cruz L. Subretinal abscess after scleral buckling surgery: a rare risk of retinal surgery. Can J Ophthalmol. 2007; 42 (1): 141–142. 16. Al-Torbak AA, Al-Shahwan S, Al-Jadaan I, AlHommadi A, Edward DP. Endophthalmitis associated with the Ahmed glaucoma valve implant. Br J Ophthalmol. 2005; 89 (4): 454–458. 17. Endophthalmitis Vitrectomy Study Group Results of the endophthalmitis vitrectomy study: a randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis. Arch Ophthalmol. 1995; 113 (12): 1479–1496. 18. Ozadamar A, Aras C, Ozturk R, Akin E, karacorlu M, Ercikan C. In vitro antimicrobial activity of silicone oil against endophthalmitis-causing agents. Retina. 1999; 19 (2): 122–126. 19. Azad R, Ravi K, Talwar D, Rajpal, Kumar N. Pars plana vitrectomy with and without silicone oil tamponade in post-traumatic endophthalmitis. Graefe’s Arch ClinExp Ophthalmol. 2003; 241 (6): 478–483. 20. Do T, Hon D, Aung T, Hien ND, Cowan CL Jr. Bacterial endogenous endophthalmitis in Vietnam: a randomized controlled trial comparing vitrectomy with silicone oil versus vitrectomy alone. Clin Ophthalmol. 2014 Aug 28; 8: 1633-40. 21. Wong JS, Chan TK, Lee HM, et al. Endogenous bacterial endophthalmitis. Ophthalmology, 2000; 107 (8): 1483–1491 22. Jackson TL, Eykyn JS, Graham EM, Graham EM, Stanford MR. Endogenous bacterial endophthalmitis: a 17-year prospective study and review of 267 reported cases. Surv Opthalmol. 2003; 48 (4): 403–423.
  • 23. Yoon YH, Lee SU, Sohn JH, Lee SE. Result of early vitrectomy for endogenous Klebsiella pneumonia endophthalmitis. Retina. 2003; 23 (3): 366–370. 24. Kuhn F, Gini G. Ten years after... are findings of the Endophthalmitis Vitrectomy Study still relevant today? Graefe’s Arch Clin Exp Ophthalmol. 2005; 243 (12): 1197–1199. 25. Cowley M, Conway BP, Campochiaro PA, kaiser D, Gaskin H. Clinical risk factors for proliferative vitreo retinopathy. Arch Ophthalmol. 1989; 107 (8): 1147–1151 26. Cowley M, Conway BP, Campochiaro PA, kaiser D, Gaskin H. Clinical risk factors for proliferative vitreoretinopathy. Arch Ophthalmol. 1989; 107 (8): 1147–1151
There are 3 citations in total.

Details

Primary Language English
Subjects Ophthalmology
Journal Section Orginal Articles
Authors

Hussain Ahmad Khaqan 0000-0002-4665-833X

Usman Imtiaz 0000-0002-8311-4059

Hasnain Muhammad Buksh 0000-0002-8622-2100

Hafiz Ateeq Rehman 0000-0002-4525-5440

Raheela Naz 0000-0003-2357-3285

Publication Date December 31, 2020
Acceptance Date December 6, 2020
Published in Issue Year 2020 Volume: 2 Issue: 3

Cite

APA Khaqan, H. A., Imtiaz, U., Buksh, H. M., Rehman, H. A., et al. (2020). Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis with or without Silicone Oil. Clinical and Experimental Ocular Trauma and Infection, 2(3), 56-60.
AMA Khaqan HA, Imtiaz U, Buksh HM, Rehman HA, Naz R. Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis with or without Silicone Oil. CEOTI. December 2020;2(3):56-60.
Chicago Khaqan, Hussain Ahmad, Usman Imtiaz, Hasnain Muhammad Buksh, Hafiz Ateeq Rehman, and Raheela Naz. “Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis With or Without Silicone Oil”. Clinical and Experimental Ocular Trauma and Infection 2, no. 3 (December 2020): 56-60.
EndNote Khaqan HA, Imtiaz U, Buksh HM, Rehman HA, Naz R (December 1, 2020) Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis with or without Silicone Oil. Clinical and Experimental Ocular Trauma and Infection 2 3 56–60.
IEEE H. A. Khaqan, U. Imtiaz, H. M. Buksh, H. A. Rehman, and R. Naz, “Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis with or without Silicone Oil”, CEOTI, vol. 2, no. 3, pp. 56–60, 2020.
ISNAD Khaqan, Hussain Ahmad et al. “Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis With or Without Silicone Oil”. Clinical and Experimental Ocular Trauma and Infection 2/3 (December 2020), 56-60.
JAMA Khaqan HA, Imtiaz U, Buksh HM, Rehman HA, Naz R. Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis with or without Silicone Oil. CEOTI. 2020;2:56–60.
MLA Khaqan, Hussain Ahmad et al. “Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis With or Without Silicone Oil”. Clinical and Experimental Ocular Trauma and Infection, vol. 2, no. 3, 2020, pp. 56-60.
Vancouver Khaqan HA, Imtiaz U, Buksh HM, Rehman HA, Naz R. Outcomes of Early Pars Plana Vitrectomy for Acute Post Operative Endophthalmitis with or without Silicone Oil. CEOTI. 2020;2(3):56-60.