Synthesis, Spectroscopic and Cytotoxic Properties of Zinc (II) and Cobalt (II) 4-Fluorobenzoate with 3-Hydroxypyridine Complexes
Year 2021,
Volume: 8 Issue: 1, 14 - 26, 30.06.2021
Mustafa Sertçelik
,
Giray Buğra Akbaba
,
Füreya Elif Öztürkkan
Abstract
In this study, two complexes of Zn (II) and Co (II) metals were synthesized with 4-fluorobenzoic acid and 3-hydroxypyridine containing N-donor atom. The structure of the two complexes synthesized was characterized by elemental analysis and FT-IR spectroscopy. The cytotoxic properties of the complexes, whose structures are determined, at the concentration range of 62,5-500 ppm were investigated using the MTT method on lymphocyte cells.
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Kobalt(II) ve Çinko(II) 4-Florobenzoatın 3-Hidroksipiridin Komplekslerinin Sentezi, Spektroskopik ve Sitotoksik Özellikleri
Year 2021,
Volume: 8 Issue: 1, 14 - 26, 30.06.2021
Mustafa Sertçelik
,
Giray Buğra Akbaba
,
Füreya Elif Öztürkkan
References
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- Bahçeci, Ş., Yıldırım, N., Gürsoy Kol, Ö., Manap, S., Beytur, M., Yüksek, H., (2016). Synthesis, characterization and antioxidant properties of new 3-alkyl (aryl)-4-(3-hydroxy-4-methoxybenzylidenamino)-4,5-dihydro-1H-1, 2, 4-triazol-5-ones. Rasayan Journal of Chemistry, 9(3), 494-501.
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https://doi.org/10.1016/j.jinorgbio.2019.110803
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- Huseynova, MT., Aliyeva, MN., Medjidov, AA., Şahin, O., Yalçın, B., (2019). Cu (II) complex with thiosemicarbazone of glyoxylic acid as an anion ligand in a polymeric structure, Journal of Molecular Structure, 1176, 895-900.
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- Krishnakumar, V., Dheivamalar S., Xavier, R. J., Balachandran, V. (2006). Analysis of vibrational spectra of 4-amino-2,6-dichloropyridine and 2-chloro-3,5-dinitropyridine based on density functional theory calculations. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; 65(1), 147-154. https://doi.org/10.1016/j.saa.2005.09.039
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- Mobinikhaledi, A., Forughifar, N., Shariatzadeh, S. M., & Fallah, M. (2006). Synthesis and antibacterial activity of some N-(3-hydroxy-2pyridyl) benzamides. Heterocyclic Communications, 12(6), 427–430.
- Mjos, K. D.and Orvig, C. (2014). Metallodrugs in medicinal inorganic chemistry. Chemical Reviews, 114(8), 4540–4563. https://doi.org/10.1021/cr400460s
- Nakamoto, K. (2006). Infrared and Raman Spectra of Inorganic and Coordination Compounds. In Handbook of Vibrational Spectroscopy. American Cancer Society. https://doi.org/10.1002/0470027320.s4104
- Nashre-ul-Islam, S. Mohd., Dutta, D., Verma, A. K., Nath, H., Frontera, A., Sharma, P., & Bhattacharyya, M. K. (2019). Antiproliferative evaluation and supramolecular association involving electrostatically enhanced π-π interaction in isostructural coordination solids of Mn(II), Co(II) and Zn(II) chlorobenzoates: Experimental and theoretical studies. Inorganica Chimica Acta, 498, 119161. https://doi.org/10.1016/j.ica.2019.119161
- Necefoğlu, H., Özbek, F. E., Öztürk, V., Tercan, B., & Hökelek, T. (2011). Bis(4-fluorobenzoato)-κ2 O,O′;κO-(4-fluorobenzoic acid-κO)bis(nicotinamide-κN1)copper(II). Acta Crystallographica Section E: Structure Reports Online, 67(Pt 7), m887–m888. https://doi.org/10.1107/S1600536811020897
- Ozbek, F. E., Sertcelik, M., Yuksek, M., Kucukoz, B., Elmali, A., & Sahin, E. (2019). Two new potential optical materials: Co(II) and Ni(II) 3-fluorobenzoate complexes with pyridine-3-carboxamide. Journal of Coordination Chemistry, 72(5–7), 786–795. https://doi.org/10.1080/00958972.2019.1590560
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- Pucci, D., Crispini, A., Mendiguchía, B. S., Pirillo, S., Ghedini, M., Morelli, S., & De Bartolo, L. (2013). Improving the bioactivity of Zn(ii)-curcumin based complexes. Dalton Transactions, 42(26), 9679. https://doi.org/10.1039/c3dt50513h
- Sertcelik, M., & Durman, M. (2020). Synthesis, Characterization, and Antibacterial Activity of Cd(II) Complexes with 3-/4-Fluorobenzoates and 3-Hydroxypiridine as Co-Ligands. Russian Journal of Inorganic Chemistry, 65(9), 1351–1359. https://doi.org/10.1134/S0036023620090168
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