2016-FM-61
In the present study, 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (3c, f, e) reacted with 4-methylthiobenzaldehyde to afford 3-alkyl(aryl)-4-(4-methylthio-benzylideneamino)-4,5-dihidro-1H-1,2,4-triazol-5-ones (4c, f, e). The structures of three new compounds were established from the elemental analysis, IR, 1H NMR, and 13C NMR spectral data. The newly synthesized and recently synthesized 3-alkyl(aryl)-4-(4-methylthiobenzylideneamino)-4,5-dihidro-1H-1,2,4-triazol-5-one derivatives were analyzed using three methods for antioxidant activities. Compound 4a showed the best activity for the metal chelating effect. Furthermore, the compounds' antimicrobial activity was screened.
The approval of an ethical committee is not required.
Scientific Research Projects Coordination Unit of Kafkas University
2016-FM-61
The authors thank Dr. Muzaffer Alkan for their contribution.
Primary Language | English |
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Subjects | Organic Chemical Synthesis |
Journal Section | Articles |
Authors | |
Project Number | 2016-FM-61 |
Publication Date | August 2, 2024 |
Submission Date | May 15, 2024 |
Acceptance Date | July 29, 2024 |
Published in Issue | Year 2024 Volume: 11 Issue: 1 |