Research Article
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The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients with Breast Cancer Receiving Chemotherapy

Year 2024, , 317 - 323, 28.06.2024
https://doi.org/10.33808/clinexphealthsci.1251705

Abstract

Objective: The research was designed experimentally to evaluate the effectiveness of progressive relaxation exercises (PRE) in the prevention of chemotherapy-induced fatigue, nausea and vomiting in patients diagnosed with breast cancer.
Methods: 50 patients diagnosed with breast cancer received doxorubicin and taxane-based treatment who applied to the chemotherapy unit of a private hospital were participated in the study. 24 patients were included in the experimental group, and 26 patients were included in the control group, who were selected by simple random method and agreed to want to get in the research. The participants in the intevention group were provided with one-to-one relaxation training accompanied by Relaxation Exercises CD of the Turkish Psychological Association before the initiation of treatment. Data were collected using “Patient Identification Form”, “Piper Fatigue Scale (PFS)” and “Rhodes Index of Nausea, Vomiting and Retching (RINVR)” forms.
Results: Most of the patients who attended in the research were married (76%) and the mean age was 52.72±10.17. A total of 54% of the participants received doxorubicin-based treatment and 46% of them was on taxane-based treatment. When we investigated the effect of PRE on fatigue, nausea and vomiting, it was found out that fatigue and “nausea, vomiting and retching (NVR) experience, occurrence and distress” scores on the day of treatment were significantly lower than those of the other five days, but there wasn’t difference in five-day symptom scores between the groups.
Conclusion: It was concluded that PRE were not an effective approach in decreasing the symptoms of fatigue, nausea, vomiting in the research group patients with breast cancer and receiving chemotherapy.

Project Number

YOK

References

  • Torre LA, Bray F, Siegel RL, Ferley J, Tieulent JL, Jemal A. Global cancer statistics, 2012 Cancer J Clin. 2015; 65(2):87–108. DOI: 10.3322/caac.21262.
  • Yeşilbalkan ÖU. Yorgunluk. Can G, editor. Onkoloji Hemşireliği. İstanbul: Nobel Tıp Kitapevleri; 2014.p.335-347 (Turkish).
  • Olver I, Carey M, Boyes A, Hall A, Noble N, Bryant J, Walsh J, Sanson-Fisher R. The timeliness of patients reporting the side effects of chemotherapy. Support Care Cancer. 2018; 26:3579–3586. DOI: 10.1007/s00520-018-4225-y.
  • Pathak P, Mahal R, Kohli A, Nimbran V. Progressive muscle relaxation: An adjuvant therapy for reducing pain and fatigue among hospitalized cancer patients receiving radiotherapy. Int J Nurs Stud Adv. 2013; 2(2):58-65. DOI:10.14419/ijans.v2i2.715.
  • American Cancer Society. What is Fatigue or Weakness? cancer.org | 1.800.227.2345. 2020 February 1 (cited 2023 december 18). Avaible from: https://www.cancer.org/content/dam/CRC/PDF/Public/7799.00.pdf.
  • Can G, Polat C. Yorgunluk. Onkoloji Hemşireliğinde Kanıttan Uygulamaya. İstanbul, Nobel Tıp Kitabevleri; 2014.p.107-121 (Turkish).
  • Prieto-Gómez V, José Yuste-Sánchez M, Bailón-Cerezo J, Romay-Barrero H, de la Rosa-Díaz I, Lirio-Romero C, Torres-Lacomba M. Effectiveness of therapeutic exercise and patient education on cancer-related fatigue in breast cancer survivors: A randomised, single-blind, controlled trial with a 6-month follow-up. J. Clin. Med. 2022;11,269. DOI:10.3390/jcm11010269.
  • Mitchell SA, Beck SL, Hood LE, Moore K, Tanner ER. Putting evidence into practice: Evidence-based interventions for fatigue during and following cancer and its treatment. Clin J Oncol Nurs. 2007; 11(1):99-113. DOI: 10.1188/07.CJON.99-113.
  • Molassiotiotis A, Yung HP, Yam BMC, Chan FYS, Mok TSK. The effectiveness of progressive muscle relaxation training in managing chemotherapy-induced nausea and vomiting in Chinese breast cancer patients: A randomised controlled trial. Support Care Cancer. 2002;10:237–246. DOI 10.1007/s00520-001-0329-9.
  • Tipton JM, McDaniel RW, Barbour L, Johnston MP, Kayne M, LeRoy P, Ripple ML. Putting evidence into practice: Evidence-based interventions to prevent, manage, and treat chemotherapy- induced nausea and vomiting. Clin J Oncol Nurs. 2007;11 (1):69-78. DOI: 10.1188/07.CJON.69-78.
  • Lorenc A, Cooke H. Progressive muscle relaxation. CAM –Cancer Consortium. March 2019 (cited 2023 december 18). Avaliable from: https://cam-cancer.org/en/progressive-muscle-relaxation.
  • Kwekkeboom K, Wanta B, Bompus M. Individual difference variables and effects of progressive muscle relaxation and analgesic imagery interventions on cancer pain. J Pain Symptom Manage 2008; 36(6): 604-615. DOI: 10.1016/j.jpainsymman.2007.12.011.
  • Isa MR, Moy FM, Razack AH, Zainuddin ZM, Zainal NZ. Impact of applied progressive deep muscle relaxation training on the level of depression, anxiety and stress among prostate cancer patients: A quasi-experimental study. Asian Pac J Cancer Prev. 2013;14(4):2237-2242. DOI: 10.7314/apjcp.2013.14.4.2237.
  • Simeit R, Deck, R and Conta-Marx, B. Sleep management training for cancer patients with insomnia. Support Care Cancer 2004; (3): 176-183. DOI: 10.1007/s00520-004-05945.
  • Genç A, Can G, Aydıner A. The efficiency of the acupressure in prevention of the chemotherapy-induced nausea and vomiting. Support Care Cancer 2013; 21:253–261. DOI: 10.1007/s00520-012-1519-3.
  • Can G. Kanser hastasında yorgunluk. Hemşirelikte Eğitim ve Araştırma Dergisi 2006;3(2):10-17 (Turkish).
  • Piper BF, Dibble SL, Dodd MJ , Weiss MC , Slaughter RE , Paul SM. The revised Piper Fatigue Scale: Psychometric evaluation in women with breast cancer. Oncol Nurs Forum1998; 25(4):677-684.
  • Can G, Durna Z, Aydıner A. Assessment of fatigue in and care needs of Turkish women with breast cancer. Cancer Nurs. 2004;27(2):153–161. DOI: 10.1097/00002820-200403000-00009.
  • Rhodes V, McDaniel R. The index of nausea, vomiting, and retching: A new format of the lndex of Nausea and Vomiting. Oncol Nurs Forum 1999;26(5):889-894.
  • Genç F, Tan M. The effect of acupressure application on chemotherapy-induced nausea, vomiting, and anxiety in patients with breast cancer. Palliat Support Care. 2015;13(2):275-284. DOI: 10.1017/S1478951514000248.
  • Navari RM. Management of chemotherapy-induced nausea and vomiting, focus on newer agents and new uses for older agents. Drugs 2013;73:249–262. DOI: 10.1007/s40265-013-0019-1.
  • Bayrak E, Can G, Kutlutürkan S, Karaman N, Ortega PF, Rassouli M, Obeidat R, Khairunnisa D, Akdemir N, Saip P. Bulantı ve kusma. Kanser Hastasında Kanıta Dayalı Palyatif Bakım. İstanbul: Nobel Tıp Kitabevleri 2018.p. 43-62 (Turkish).
  • Hesketh PJ, Bohlke K, Kris MG. Antiemetics: American society of clinical oncology focused guideline update. J Oncol Pract. 2016; 12 (1): 88-90.
  • Rhodes VA, McDaniel RW. Nausea, vomiting, and retching: Complex problems in palliative care. CA Cancer J Clin. 2001; 51:232-248. DOI: 10.3322/canjclin.51.4.232.
  • Arslan M, Özdemir L. Kemoterapiye bağlı gelişen bulantı-kusmanın yönetiminde kullanılan tamamlayıcı tedavi yöntemleri. Türk Onkoloji Dergisi 2015; 30(2):82-89. DOI: 10.5505/tjoncol.2015.1204 (Turkish).
  • Demiralp MF, Oflaz F, Komurcu S. Effects of relaxation training on sleep quality and fatigue in patients with breast cancer undergoing adjuvant chemotherapy. J Clin Nurs. 2010;19(7-8):1073-1083. DOI: 10.1111/j.1365-2702.2009.03037.x.
  • Doğan S, Tel H, Özkan M. Gevşeme egzersizinin adjuvan kemoterapi alan meme ve kolorektal kanser tanılı hastaların yorgunluk, depresyon ve yaşam kalitesi düzeyine etkisi. Gevher Nesibe Journal of Medical & Health Sciences 2020;5(8):133-145. DOI: 0.46648/gnj.143 (Turkish).
  • Alan Dikmen H, Terzioğlu F. Effects of reflexology and progressive muscle relaxation on pain, fatigue, and quality of life during chemotherapy in gynecologic cancer patients. Pain Manag Nurs. 2019;20(1):47-53. DOI: 10.1016/j.pmn.2018.03.001.
  • Soliman HM, Eltantawy A, El-Kurdy R. The effect of progressive muscle relaxation training on chemotherapy-induced nausea, vomiting and anxiety in Egyptian breast cancer women: A randomized controlled trial. Journal of Nursing Education and Practice. 2022;12 (4):1-11. DOI: https://doi.org/10.5430/jnep.v12n4p1.
  • Carvalho EC, Martins FTM, Santos CB. A Pilot study of a relaxation technique for management of nausea and vomiting in patients receiving cancer chemotherapy. Cancer Nurs. 2007;30 (2):163-167. DOI: 10.1097/01.NCC.0000265007.87311.d0.
  • Gupta B, Kumari M, Kaur T. Effectiveness of progressive muscle relaxation technique on physical symptoms among patients receiving chemotherapy. Nursing and Midwifery Research Journal 2016;12(1):33-40. DOI: 10.33698/NRF0195.
  • Tian X, Ying Tang R, Li Xu L, Xie W, Chen H, Ping Pi Y, Qing Chen W. Progressive muscle relaxation is effective in preventing and alleviating of chemotherapy-induced nausea and vomiting among cancer patients: A systematic review of six randomized controlled trials. Support Care Cancer. 2020;28(9):4051-4058. DOI: 10.1007/s00520-020-05481-2.
  • Song QH, Xu RM, Zhang QH, Ma M, Zhao X. Relaxation training during chemohterapy for breast cancer improves mental health and lessens adverse events. Int J Clin Exp Med. 2013; 6(10):979-984.
  • Kurt B, Kapucu S. The effect of relaxation exercises on symptom severity in patients with breast cancer undergoing adjuvant chemotherapy: An open label non-randomized controlled clinical trial. Eur J Integr Med. 2018; 22:54-61. DOI:10.1016/j.eujim.2018.08.002.
  • Arakawa S. Use of relaxation to reduce side effects of chemotherapy in Japanese patients. Cancer Nurs. 1995; 18(1):60-66.
  • Young-Jae K, Nam-Sook S. Effects of progressive muscle relaxation on nausea, vomiting, fatigue, anxiety and depression in cancer patients undergoing chemotherapy. J Korean Oncol Nurs. 2010;10(2): 171-179. DOI:10.5388/jkon.2010.10.2.171.
Year 2024, , 317 - 323, 28.06.2024
https://doi.org/10.33808/clinexphealthsci.1251705

Abstract

Supporting Institution

YOK

Project Number

YOK

Thanks

YOK

References

  • Torre LA, Bray F, Siegel RL, Ferley J, Tieulent JL, Jemal A. Global cancer statistics, 2012 Cancer J Clin. 2015; 65(2):87–108. DOI: 10.3322/caac.21262.
  • Yeşilbalkan ÖU. Yorgunluk. Can G, editor. Onkoloji Hemşireliği. İstanbul: Nobel Tıp Kitapevleri; 2014.p.335-347 (Turkish).
  • Olver I, Carey M, Boyes A, Hall A, Noble N, Bryant J, Walsh J, Sanson-Fisher R. The timeliness of patients reporting the side effects of chemotherapy. Support Care Cancer. 2018; 26:3579–3586. DOI: 10.1007/s00520-018-4225-y.
  • Pathak P, Mahal R, Kohli A, Nimbran V. Progressive muscle relaxation: An adjuvant therapy for reducing pain and fatigue among hospitalized cancer patients receiving radiotherapy. Int J Nurs Stud Adv. 2013; 2(2):58-65. DOI:10.14419/ijans.v2i2.715.
  • American Cancer Society. What is Fatigue or Weakness? cancer.org | 1.800.227.2345. 2020 February 1 (cited 2023 december 18). Avaible from: https://www.cancer.org/content/dam/CRC/PDF/Public/7799.00.pdf.
  • Can G, Polat C. Yorgunluk. Onkoloji Hemşireliğinde Kanıttan Uygulamaya. İstanbul, Nobel Tıp Kitabevleri; 2014.p.107-121 (Turkish).
  • Prieto-Gómez V, José Yuste-Sánchez M, Bailón-Cerezo J, Romay-Barrero H, de la Rosa-Díaz I, Lirio-Romero C, Torres-Lacomba M. Effectiveness of therapeutic exercise and patient education on cancer-related fatigue in breast cancer survivors: A randomised, single-blind, controlled trial with a 6-month follow-up. J. Clin. Med. 2022;11,269. DOI:10.3390/jcm11010269.
  • Mitchell SA, Beck SL, Hood LE, Moore K, Tanner ER. Putting evidence into practice: Evidence-based interventions for fatigue during and following cancer and its treatment. Clin J Oncol Nurs. 2007; 11(1):99-113. DOI: 10.1188/07.CJON.99-113.
  • Molassiotiotis A, Yung HP, Yam BMC, Chan FYS, Mok TSK. The effectiveness of progressive muscle relaxation training in managing chemotherapy-induced nausea and vomiting in Chinese breast cancer patients: A randomised controlled trial. Support Care Cancer. 2002;10:237–246. DOI 10.1007/s00520-001-0329-9.
  • Tipton JM, McDaniel RW, Barbour L, Johnston MP, Kayne M, LeRoy P, Ripple ML. Putting evidence into practice: Evidence-based interventions to prevent, manage, and treat chemotherapy- induced nausea and vomiting. Clin J Oncol Nurs. 2007;11 (1):69-78. DOI: 10.1188/07.CJON.69-78.
  • Lorenc A, Cooke H. Progressive muscle relaxation. CAM –Cancer Consortium. March 2019 (cited 2023 december 18). Avaliable from: https://cam-cancer.org/en/progressive-muscle-relaxation.
  • Kwekkeboom K, Wanta B, Bompus M. Individual difference variables and effects of progressive muscle relaxation and analgesic imagery interventions on cancer pain. J Pain Symptom Manage 2008; 36(6): 604-615. DOI: 10.1016/j.jpainsymman.2007.12.011.
  • Isa MR, Moy FM, Razack AH, Zainuddin ZM, Zainal NZ. Impact of applied progressive deep muscle relaxation training on the level of depression, anxiety and stress among prostate cancer patients: A quasi-experimental study. Asian Pac J Cancer Prev. 2013;14(4):2237-2242. DOI: 10.7314/apjcp.2013.14.4.2237.
  • Simeit R, Deck, R and Conta-Marx, B. Sleep management training for cancer patients with insomnia. Support Care Cancer 2004; (3): 176-183. DOI: 10.1007/s00520-004-05945.
  • Genç A, Can G, Aydıner A. The efficiency of the acupressure in prevention of the chemotherapy-induced nausea and vomiting. Support Care Cancer 2013; 21:253–261. DOI: 10.1007/s00520-012-1519-3.
  • Can G. Kanser hastasında yorgunluk. Hemşirelikte Eğitim ve Araştırma Dergisi 2006;3(2):10-17 (Turkish).
  • Piper BF, Dibble SL, Dodd MJ , Weiss MC , Slaughter RE , Paul SM. The revised Piper Fatigue Scale: Psychometric evaluation in women with breast cancer. Oncol Nurs Forum1998; 25(4):677-684.
  • Can G, Durna Z, Aydıner A. Assessment of fatigue in and care needs of Turkish women with breast cancer. Cancer Nurs. 2004;27(2):153–161. DOI: 10.1097/00002820-200403000-00009.
  • Rhodes V, McDaniel R. The index of nausea, vomiting, and retching: A new format of the lndex of Nausea and Vomiting. Oncol Nurs Forum 1999;26(5):889-894.
  • Genç F, Tan M. The effect of acupressure application on chemotherapy-induced nausea, vomiting, and anxiety in patients with breast cancer. Palliat Support Care. 2015;13(2):275-284. DOI: 10.1017/S1478951514000248.
  • Navari RM. Management of chemotherapy-induced nausea and vomiting, focus on newer agents and new uses for older agents. Drugs 2013;73:249–262. DOI: 10.1007/s40265-013-0019-1.
  • Bayrak E, Can G, Kutlutürkan S, Karaman N, Ortega PF, Rassouli M, Obeidat R, Khairunnisa D, Akdemir N, Saip P. Bulantı ve kusma. Kanser Hastasında Kanıta Dayalı Palyatif Bakım. İstanbul: Nobel Tıp Kitabevleri 2018.p. 43-62 (Turkish).
  • Hesketh PJ, Bohlke K, Kris MG. Antiemetics: American society of clinical oncology focused guideline update. J Oncol Pract. 2016; 12 (1): 88-90.
  • Rhodes VA, McDaniel RW. Nausea, vomiting, and retching: Complex problems in palliative care. CA Cancer J Clin. 2001; 51:232-248. DOI: 10.3322/canjclin.51.4.232.
  • Arslan M, Özdemir L. Kemoterapiye bağlı gelişen bulantı-kusmanın yönetiminde kullanılan tamamlayıcı tedavi yöntemleri. Türk Onkoloji Dergisi 2015; 30(2):82-89. DOI: 10.5505/tjoncol.2015.1204 (Turkish).
  • Demiralp MF, Oflaz F, Komurcu S. Effects of relaxation training on sleep quality and fatigue in patients with breast cancer undergoing adjuvant chemotherapy. J Clin Nurs. 2010;19(7-8):1073-1083. DOI: 10.1111/j.1365-2702.2009.03037.x.
  • Doğan S, Tel H, Özkan M. Gevşeme egzersizinin adjuvan kemoterapi alan meme ve kolorektal kanser tanılı hastaların yorgunluk, depresyon ve yaşam kalitesi düzeyine etkisi. Gevher Nesibe Journal of Medical & Health Sciences 2020;5(8):133-145. DOI: 0.46648/gnj.143 (Turkish).
  • Alan Dikmen H, Terzioğlu F. Effects of reflexology and progressive muscle relaxation on pain, fatigue, and quality of life during chemotherapy in gynecologic cancer patients. Pain Manag Nurs. 2019;20(1):47-53. DOI: 10.1016/j.pmn.2018.03.001.
  • Soliman HM, Eltantawy A, El-Kurdy R. The effect of progressive muscle relaxation training on chemotherapy-induced nausea, vomiting and anxiety in Egyptian breast cancer women: A randomized controlled trial. Journal of Nursing Education and Practice. 2022;12 (4):1-11. DOI: https://doi.org/10.5430/jnep.v12n4p1.
  • Carvalho EC, Martins FTM, Santos CB. A Pilot study of a relaxation technique for management of nausea and vomiting in patients receiving cancer chemotherapy. Cancer Nurs. 2007;30 (2):163-167. DOI: 10.1097/01.NCC.0000265007.87311.d0.
  • Gupta B, Kumari M, Kaur T. Effectiveness of progressive muscle relaxation technique on physical symptoms among patients receiving chemotherapy. Nursing and Midwifery Research Journal 2016;12(1):33-40. DOI: 10.33698/NRF0195.
  • Tian X, Ying Tang R, Li Xu L, Xie W, Chen H, Ping Pi Y, Qing Chen W. Progressive muscle relaxation is effective in preventing and alleviating of chemotherapy-induced nausea and vomiting among cancer patients: A systematic review of six randomized controlled trials. Support Care Cancer. 2020;28(9):4051-4058. DOI: 10.1007/s00520-020-05481-2.
  • Song QH, Xu RM, Zhang QH, Ma M, Zhao X. Relaxation training during chemohterapy for breast cancer improves mental health and lessens adverse events. Int J Clin Exp Med. 2013; 6(10):979-984.
  • Kurt B, Kapucu S. The effect of relaxation exercises on symptom severity in patients with breast cancer undergoing adjuvant chemotherapy: An open label non-randomized controlled clinical trial. Eur J Integr Med. 2018; 22:54-61. DOI:10.1016/j.eujim.2018.08.002.
  • Arakawa S. Use of relaxation to reduce side effects of chemotherapy in Japanese patients. Cancer Nurs. 1995; 18(1):60-66.
  • Young-Jae K, Nam-Sook S. Effects of progressive muscle relaxation on nausea, vomiting, fatigue, anxiety and depression in cancer patients undergoing chemotherapy. J Korean Oncol Nurs. 2010;10(2): 171-179. DOI:10.5388/jkon.2010.10.2.171.
There are 36 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases Nursing​
Journal Section Articles
Authors

Aslı Genç 0000-0003-4499-4708

Sıdıka Oğuz 0000-0002-1101-1923

Project Number YOK
Publication Date June 28, 2024
Submission Date February 15, 2023
Published in Issue Year 2024

Cite

APA Genç, A., & Oğuz, S. (2024). The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients with Breast Cancer Receiving Chemotherapy. Clinical and Experimental Health Sciences, 14(2), 317-323. https://doi.org/10.33808/clinexphealthsci.1251705
AMA Genç A, Oğuz S. The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients with Breast Cancer Receiving Chemotherapy. Clinical and Experimental Health Sciences. June 2024;14(2):317-323. doi:10.33808/clinexphealthsci.1251705
Chicago Genç, Aslı, and Sıdıka Oğuz. “The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients With Breast Cancer Receiving Chemotherapy”. Clinical and Experimental Health Sciences 14, no. 2 (June 2024): 317-23. https://doi.org/10.33808/clinexphealthsci.1251705.
EndNote Genç A, Oğuz S (June 1, 2024) The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients with Breast Cancer Receiving Chemotherapy. Clinical and Experimental Health Sciences 14 2 317–323.
IEEE A. Genç and S. Oğuz, “The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients with Breast Cancer Receiving Chemotherapy”, Clinical and Experimental Health Sciences, vol. 14, no. 2, pp. 317–323, 2024, doi: 10.33808/clinexphealthsci.1251705.
ISNAD Genç, Aslı - Oğuz, Sıdıka. “The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients With Breast Cancer Receiving Chemotherapy”. Clinical and Experimental Health Sciences 14/2 (June 2024), 317-323. https://doi.org/10.33808/clinexphealthsci.1251705.
JAMA Genç A, Oğuz S. The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients with Breast Cancer Receiving Chemotherapy. Clinical and Experimental Health Sciences. 2024;14:317–323.
MLA Genç, Aslı and Sıdıka Oğuz. “The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients With Breast Cancer Receiving Chemotherapy”. Clinical and Experimental Health Sciences, vol. 14, no. 2, 2024, pp. 317-23, doi:10.33808/clinexphealthsci.1251705.
Vancouver Genç A, Oğuz S. The Effect of Progressive Relaxation Exercises on Fatigue, Nausea and Vomiting in Patients with Breast Cancer Receiving Chemotherapy. Clinical and Experimental Health Sciences. 2024;14(2):317-23.

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