Year 2011,
Volume: 1 Issue: 3, 149 - 154, 31.01.2014
Abstract
Esrarın kullanımı çok eskilere dayanmasına rağmen biyolojik mekanizmalarının aydınlatılabilmesi için araştırmalar halen devam etmektedir. Esrarın psikoaktif bileşeni olan Δ9-Tetrahydrocannabinol (THC), sentetik analogları ve endojen lipid türevleri vücutta kannabinoid reseptörlerine bağlanırlar. Endokannabinoid sistem, merkezi sinir sisteminde ve periferdeki homeostazisi sağlayıcı rollerinden dolayı patofizyolojik durumlarda da oldukça önemlidirler. Bu yazıda endokannabinoid sistem ve terapötik önemi özetlenmiştir.
Anahtar Kelimeler : Esrar, endokannabinoidler, kannabinoid reseptör, CB1, anandamide
Year 2011,
Volume: 1 Issue: 3, 149 - 154, 31.01.2014
Abstract
Although marihuana has been used for many years, clarifications on its biological mechanisms are still going on. Δ9-Tetrahidrokannabinol (THC) the psychoactive component of marihuana, synthetic analogs and endogenous lipid derivatives bind to cannabinoid receptor. The endocannabinoid system is very important in the pathophysiological conditions due to their role for regulation of the homeostasis mainly in the central nervous system and the periphery. The endocannabinoid system and its therapeutic applications are briefly summarized here.
Key words: Marihuana, endocannabinoids, cannabinoid receptor, CB1, anandamid
Keywords
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Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | January 31, 2014 |
| Submission Date | November 3, 2013 |
| Published in Issue | Year 2011 Volume: 1 Issue: 3 |
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