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Intraventricular conduction blocks in Nigerians with hypertensive heart disease

Year 2013, Volume: 3 Issue: 2, 69 - 74, 30.01.2014

Abstract

Background: Hypertension is highly prevalent in Nigeria and globally. Intraventricular conduction blocks contribute to morbidity and mortality in hypertension. The objective of the study was to determine the prevalence and pattern of intraventricular conduction blocks in adult Nigerians with hypertensive heart disease.

Materials and methods: This was a retrospective study of the resting 12-lead electrocardiograms of adult patients with hypertensive heart disease attending the Cardiology Unit of the Federal Medical Centre (FMC), Ido-Ekiti, Nigeria. The data collected was doubly entry into SPSS 20.0 software. 

Results: Resting electrocardiograms of 543 adult Nigerians with hypertensive heart disease were studied. There were 336 (61.9%) males and 207 (38.1%) females. Mean age and standard deviation of the patients was 61.3±9.7 years. About a quarter (24.7%) of the patients had intraventricular conduction blocks. Left anterior fascicular block was the most common (52.2%) occurring singly or in combinations with other blocks. Intraventricular conduction blocks were more prevalent in patients with hypertensive heart failure (31.0% versus 23.9%, p = 0.24)though not statistically significant. 

Conclusion: This study shows that there is a high prevalence of intraventricular conduction blocks in adult Nigerians with hypertensive heart disease. The subset with heart failure has a higher prevalence than those without heart failure. Left anterior fascicular block is the most common type.


Key words: Hypertension, heart failure, intraventricular conduction blocks, adult Nigerians

References

  • Wolf-Maier K, Cooper RS, Banegas JR, Giampaoli S, Hense HW, Joffres M, Kastarinen M, Poulter N, Primatesta P, Rodríguez-Artalejo F, Stegmayr B, Thamm M, Tuomilehto J, Vanuzzo D, Vescio F. Hypertension prevalence and blood pressure levels in six European countries, Canada, and the United States. JAMA. 2003; 289:2363-9. González-Juanatey JR, Alegría E, Lozano JV, Llisterri JL, García-Acuña JM, González-Maqueda I. Impacto de la hipertensiónen las cardiopatías en España. Estudio Cardiotens’99. Rev Esp Cardiol. 2001; 54:139-49. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005; 365(9455): 217-223.
  • Adedoyin RA, Mbada CE, Balogun MO, Martins T, Adebayo RA, Akintomide A, Akinwusi PO. Prevalence and pattern of hypertension in a semiurban community in Nigeria. Eur J Cardiovasc Prev Rehabil. 2008; 15(6): 683-687.
  • Ofuya Z. The incidence of hypertension among a select population of adults in the Niger Delta region of Nigeria. Southeast Asian J Trop Med Public Health. 2007; 38(5): 947-949.
  • Oladipo B, Akinkungbe. Current epidemiology of hypertension in Nigeria. Arch Ibadan Med. 2001; 1(1): 4-8.
  • Oladapo OO, Salako L, Sodiq O, Shoyinka K, Adedapo K, Falase AO. A prevalence of cardiometabolic risk factors among a rural Yoruba south-western Nigerian population: a population-based survey. Cardiovasc J Afr. 2010; 21(1): 26-31.
  • Díez J, González A, López B, Querejeta R. Mechanisms of disease: pathologic structural remodeling is more than adaptive hypertrophy in hypertensive heart disease. Nat Clin Pract Cardiovasc Med. 2005; 2: 209-2
  • Gosse P. Left ventricular hypertrophy as a predictor of cardiovascular risk. J Hypertens. 2005 (Suppl.); 23: 27-33.
  • Mensah GA, Croft JB, Giles WH. The heart, kidney, and brain as target organs in hypertension. Cardiol Clin. 2002; 20: 225-247.
  • Tin LL, Beevers DG, Lip GY. Hypertension, left ventricular hypertrophy, and sudden death. Curr Cardiol Re. 2002; 4: 449-457.
  • Struijker Boudier HA, Cohuet GM, Baumann M, Safar ME. The heart, macrocirculation and microcirculation in hypertension: a unifying hypothesis. J Hypertens. 2003 (Suppl.); 21: 19-23.
  • Vázquez Ruiz de Castroviejo E, Sánchez Perales C, López López J, García Cortés MJ, Aragón Extremera V, Guzmán Herrera M, Fajardo Pineda A, Lozano Cabezas C. Prevalence of and Predisposing Factors for Bundle Branch Block in Patients Starting Dialysis. Rev Esp Cardiol. 2008; 61:719-725.
  • Aje A, Adebiyi AA, Falase AO. Hypertensive heart disease in Africa. SA Heart J. 2009; 6:42-51.
  • Mensah GA, Barkley NL, Cooper RS. Spectrum of hypertensive target organ damage in Africa: a review of published studies. J Hum Hypertens. 1994; 8: 799-808.
  • Opadijo OG, Omotoso ABO, Araoye MA. Prognostic significance of intraventricular conduction blocks in adult Nigerians with hypertensive heart disease. Nig J Med. 2000; 9(4): 130-133.
  • Mullins CB, Atkins JM, Prognosis and management of ventricular conduction block in acute myocardial infarction. Mod Concepts Cardiovasc Dis. 1996; 45(10): 129-133.
  • Dubois C, Pierard LA, Smeets JP, Foidart G, Legrand V, Kulbertus HE. Short and long term prognostic importance of complete bundle branch block complicating acute myocardial infarction. Clin Cardiol. 1988; 11: 292-296.
  • Cases A. Riñón y enfermedad cardiovascular. Nephrologie. 2004; 24 Suppl 6:62-72.
  • Elizari MV, Acunzo RS, Ferreiro M. Heart blocks revisited. Circulation. 2007; 115(9): 1154-1163.
  • Horwitz S, Lupi E, Hayes J, Frishmen W, Cardenas M, Killip T. Electrocardiographic criteria for the diagnosis of left anterior fascicular block, left atrial deviation and delayed intraventricular conduction. Chest. 1975; 68(3): 317-320.

Hipertansif kalp hastalığı olan Nijeryalılar’da intraventriküler iletim blokları

Year 2013, Volume: 3 Issue: 2, 69 - 74, 30.01.2014

Abstract

Amaç: Hipertansiyon tüm dünyada olduğu gibi Nijerya’da da yüksek prevalansa sahiptir. İntraventriküler iletim bloklarının hipertansiyonda morbidite ve mortaliteye katkıda bulunduğu bilinmektedir. Bu çalışmanın amacı, hipertansif kalp hastalığı olan erişkin Nijeryalılar’da intraventriküler iletim blok prevalansı ve kalıbının belirlenmesidir.

Gereç ve Yöntem: Bu retrospektif çalışma, Ido-Ekiti, Nijerya’daki Federal Tıp Merkezi’nin Kardiyoloji Birimi’ne başvurmuş olan, hipertansif kalp hastalığına sahip erişkin hastaların istirahat halindeki 12-derivasyonlu elektrokardiyogramlarının değerlendirilmesini kapsamaktaydı. Toplanan veriler SPSS 20.0 yazılımı ile analiz edilmiştir.

Bulgular: Hipertansif kalp hastalığı olan 543 erişkin Nijeryalı’nın istirahat halindeki elektrokardiyogramları çalışıldı. 336’sı (%61.9) erkek ve 207’si (%38.1) kadın olan hastaların ortalama ± standart sapma yaşları 61.3±9.7 yıl idi. Hastaların yaklaşık dörtte birinde (%24.7) intraventriküler iletim blokları vardı. Sol ön fasiküler blok tek başına ya da diğer bloklar ile kombinasyon halinde en sık gözlenen (%52.2) blok türüydü. İntraventriküler ileti blokları hipertansif kalp yetmezliği olan hastalarda istatistiksel olarak anlamlı olmasa da daha sık görülmekteydi (%23.9’a karşı %31.0, p=0.24).

Sonuç: Bu çalışma hipertansif kalp hastalığı olan erişkin Nijeryalılar’da intraventriküler iletim blok prevalansının yüksek olduğunu göstermektedir. Kalp yetmezliği olan alt-grup, kalp yetmezliği olmayanlara göre daha yüksek bir prevalansa sahipti. En sık görülen blok tip sol ön fasiküler bloktu.


Anahtar Kelimeler : Hipertansiyon, kalp yetmezliği, intraventriküler ileti blokları, yetişkin Nijeryalılar

References

  • Wolf-Maier K, Cooper RS, Banegas JR, Giampaoli S, Hense HW, Joffres M, Kastarinen M, Poulter N, Primatesta P, Rodríguez-Artalejo F, Stegmayr B, Thamm M, Tuomilehto J, Vanuzzo D, Vescio F. Hypertension prevalence and blood pressure levels in six European countries, Canada, and the United States. JAMA. 2003; 289:2363-9. González-Juanatey JR, Alegría E, Lozano JV, Llisterri JL, García-Acuña JM, González-Maqueda I. Impacto de la hipertensiónen las cardiopatías en España. Estudio Cardiotens’99. Rev Esp Cardiol. 2001; 54:139-49. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005; 365(9455): 217-223.
  • Adedoyin RA, Mbada CE, Balogun MO, Martins T, Adebayo RA, Akintomide A, Akinwusi PO. Prevalence and pattern of hypertension in a semiurban community in Nigeria. Eur J Cardiovasc Prev Rehabil. 2008; 15(6): 683-687.
  • Ofuya Z. The incidence of hypertension among a select population of adults in the Niger Delta region of Nigeria. Southeast Asian J Trop Med Public Health. 2007; 38(5): 947-949.
  • Oladipo B, Akinkungbe. Current epidemiology of hypertension in Nigeria. Arch Ibadan Med. 2001; 1(1): 4-8.
  • Oladapo OO, Salako L, Sodiq O, Shoyinka K, Adedapo K, Falase AO. A prevalence of cardiometabolic risk factors among a rural Yoruba south-western Nigerian population: a population-based survey. Cardiovasc J Afr. 2010; 21(1): 26-31.
  • Díez J, González A, López B, Querejeta R. Mechanisms of disease: pathologic structural remodeling is more than adaptive hypertrophy in hypertensive heart disease. Nat Clin Pract Cardiovasc Med. 2005; 2: 209-2
  • Gosse P. Left ventricular hypertrophy as a predictor of cardiovascular risk. J Hypertens. 2005 (Suppl.); 23: 27-33.
  • Mensah GA, Croft JB, Giles WH. The heart, kidney, and brain as target organs in hypertension. Cardiol Clin. 2002; 20: 225-247.
  • Tin LL, Beevers DG, Lip GY. Hypertension, left ventricular hypertrophy, and sudden death. Curr Cardiol Re. 2002; 4: 449-457.
  • Struijker Boudier HA, Cohuet GM, Baumann M, Safar ME. The heart, macrocirculation and microcirculation in hypertension: a unifying hypothesis. J Hypertens. 2003 (Suppl.); 21: 19-23.
  • Vázquez Ruiz de Castroviejo E, Sánchez Perales C, López López J, García Cortés MJ, Aragón Extremera V, Guzmán Herrera M, Fajardo Pineda A, Lozano Cabezas C. Prevalence of and Predisposing Factors for Bundle Branch Block in Patients Starting Dialysis. Rev Esp Cardiol. 2008; 61:719-725.
  • Aje A, Adebiyi AA, Falase AO. Hypertensive heart disease in Africa. SA Heart J. 2009; 6:42-51.
  • Mensah GA, Barkley NL, Cooper RS. Spectrum of hypertensive target organ damage in Africa: a review of published studies. J Hum Hypertens. 1994; 8: 799-808.
  • Opadijo OG, Omotoso ABO, Araoye MA. Prognostic significance of intraventricular conduction blocks in adult Nigerians with hypertensive heart disease. Nig J Med. 2000; 9(4): 130-133.
  • Mullins CB, Atkins JM, Prognosis and management of ventricular conduction block in acute myocardial infarction. Mod Concepts Cardiovasc Dis. 1996; 45(10): 129-133.
  • Dubois C, Pierard LA, Smeets JP, Foidart G, Legrand V, Kulbertus HE. Short and long term prognostic importance of complete bundle branch block complicating acute myocardial infarction. Clin Cardiol. 1988; 11: 292-296.
  • Cases A. Riñón y enfermedad cardiovascular. Nephrologie. 2004; 24 Suppl 6:62-72.
  • Elizari MV, Acunzo RS, Ferreiro M. Heart blocks revisited. Circulation. 2007; 115(9): 1154-1163.
  • Horwitz S, Lupi E, Hayes J, Frishmen W, Cardenas M, Killip T. Electrocardiographic criteria for the diagnosis of left anterior fascicular block, left atrial deviation and delayed intraventricular conduction. Chest. 1975; 68(3): 317-320.
There are 19 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Olusegun Adesola Busari This is me

Abidemi Jude Fasae This is me

Timothy Olusegun Olarewaju This is me

Lawrence Majekodunmi Ayodele This is me

Yusuf Olatunji Oladosu This is me

Publication Date January 30, 2014
Submission Date January 30, 2014
Published in Issue Year 2013 Volume: 3 Issue: 2

Cite

APA Busari, O. A., Fasae, A. J., Olarewaju, T. O., Ayodele, L. M., et al. (2014). Hipertansif kalp hastalığı olan Nijeryalılar’da intraventriküler iletim blokları. Clinical and Experimental Health Sciences, 3(2), 69-74. https://doi.org/10.5455/musbed.20130611090623
AMA Busari OA, Fasae AJ, Olarewaju TO, Ayodele LM, Oladosu YO. Hipertansif kalp hastalığı olan Nijeryalılar’da intraventriküler iletim blokları. Clinical and Experimental Health Sciences. February 2014;3(2):69-74. doi:10.5455/musbed.20130611090623
Chicago Busari, Olusegun Adesola, Abidemi Jude Fasae, Timothy Olusegun Olarewaju, Lawrence Majekodunmi Ayodele, and Yusuf Olatunji Oladosu. “Hipertansif Kalp hastalığı Olan Nijeryalılar’da intraventriküler Iletim Blokları”. Clinical and Experimental Health Sciences 3, no. 2 (February 2014): 69-74. https://doi.org/10.5455/musbed.20130611090623.
EndNote Busari OA, Fasae AJ, Olarewaju TO, Ayodele LM, Oladosu YO (February 1, 2014) Hipertansif kalp hastalığı olan Nijeryalılar’da intraventriküler iletim blokları. Clinical and Experimental Health Sciences 3 2 69–74.
IEEE O. A. Busari, A. J. Fasae, T. O. Olarewaju, L. M. Ayodele, and Y. O. Oladosu, “Hipertansif kalp hastalığı olan Nijeryalılar’da intraventriküler iletim blokları”, Clinical and Experimental Health Sciences, vol. 3, no. 2, pp. 69–74, 2014, doi: 10.5455/musbed.20130611090623.
ISNAD Busari, Olusegun Adesola et al. “Hipertansif Kalp hastalığı Olan Nijeryalılar’da intraventriküler Iletim Blokları”. Clinical and Experimental Health Sciences 3/2 (February 2014), 69-74. https://doi.org/10.5455/musbed.20130611090623.
JAMA Busari OA, Fasae AJ, Olarewaju TO, Ayodele LM, Oladosu YO. Hipertansif kalp hastalığı olan Nijeryalılar’da intraventriküler iletim blokları. Clinical and Experimental Health Sciences. 2014;3:69–74.
MLA Busari, Olusegun Adesola et al. “Hipertansif Kalp hastalığı Olan Nijeryalılar’da intraventriküler Iletim Blokları”. Clinical and Experimental Health Sciences, vol. 3, no. 2, 2014, pp. 69-74, doi:10.5455/musbed.20130611090623.
Vancouver Busari OA, Fasae AJ, Olarewaju TO, Ayodele LM, Oladosu YO. Hipertansif kalp hastalığı olan Nijeryalılar’da intraventriküler iletim blokları. Clinical and Experimental Health Sciences. 2014;3(2):69-74.

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